Results 71 to 80 of about 523,879 (387)

Probing protein sequences as sources for encrypted antimicrobial peptides [PDF]

, 2012
Starting from the premise that a wealth of potentially biologically active peptides may lurk within proteins, we describe here a methodology to identify putative antimicrobial peptides encrypted in protein sequences.
Alan Cooper, Carlos Bloch, Eugene A. Permyakov, Francisco J. L. Aragão, Guilherme D. Brand, Jacques Nicoli, Maria L. P. Tinoco, Mariana T. Q. Magalhães, Sharon M. Kelly   +8 more
core   +3 more sources

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Essential Phospholipids in the Treatment of the Metabolic Syndrome

Медицинский вестник Юга России, 2012
Purpose: to prove the appointment of essential phospholipids in the metabolic syndrome. 1 molecule of phospholipid dissolves the 3 molecules of cholesterol and removes it from the body.
E. N. Veselova, E. E. Alekseev, L. S. Mkrtchyan   +2 more
doaj  

Egg Phospholipids and Cardiovascular Health

Nutrients, 2015
Eggs are a major source of phospholipids (PL) in the Western diet. Dietary PL have emerged as a potential source of bioactive lipids that may have widespread effects on pathways related to inflammation, cholesterol metabolism, and high-density ...
C. Blesso
semanticscholar   +1 more source

Determination of the Main Phase Transition Temperature of Phospholipids by Oscillatory Rheology

Molecules, 2023
Knowledge of the physical and chemical properties of phospholipids, such as phase transition temperatures (Tc), is of great importance in order to reveal the functionalities of biological and artificial membranes.
Lívia Budai, Marianna Budai, Tamás Bozó, Gergely Agócs, Miklós Kellermayer, István Antal   +5 more
doaj   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

PENGARUH KOMPOSOSI LAPISAN PADA PERMUKAAN GLOBULA MINYAK EMULSI SEBELUM PENGERINGAN SEMPROT TERHADAP SIFAT-SIFAT MIKROKAMSUL TRIGLISERIDA KAYA ASAM LEMAK W-3 [The Effect of the Composition of Adsorbed Layer at Globule Interface of -3 Fatty Acids Enriched Triglyceride Prior to Spray Drying on its Microcapsule Properties]

Jurnal Teknologi dan Industri Pangan, 2005
Emulsification is the critical factor in microencapsulation by spray drying method. Sodium caseinate is a protein with good emulsifying properties. The properties could be improved by phospholipids addition in the emulsification.
Moch Adnan2), Teti Estiasih1), Teti Estiasih1), Moch Adnan2), Tranggono2), Tranggono2), Suparmo2), Suparmo2)   +7 more
doaj  

Physical and chemical processes and the morphofunctional characteristics of human erythrocytes in hyperglycaemia [PDF]

, 2017
Background: This study examines the effect of graduated hyperglycaemia on the state and oxygen-binding ability of hemoglobin, the correlation of phospholipid fractions and their metabolites in the membrane, the activity of proteolytic enzymes and the ...
Bourdon, Jean Christophe, Gromova, Natalia V., Grunyushkin, Igor P., Klenova, Natalia A., Pestryakova, Anastasia A., Prosnikova, Ksenia V., Revin, Victor V., Revina, Elvira S., Sadykhova, Anna V., Solomadin, Ilia N., Tychkov, Alexander Y., Zhelev, Nikolai   +11 more
core   +5 more sources

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Regulation of neutral cholesterol esterase activity by phospholipids containing negative charges in substrate liposome

Journal of Lipid Research, 1995
The effect of phospholipids on cholesteryl ester hydrolysis by neutral cholesterol esterase in alveolar macrophages was studied. Among the phospholipids used as emulsifiers, those with a negative charge, such as phosphatidylserine, phosphatidic acid ...
I Ishii, R Onozaki, E Takahashi, S Takahashi, N Fujio, T Harada, N Morisaki, K Shirai, Y Saito, S Hirose   +9 more
doaj   +1 more source