Results 81 to 90 of about 228,764 (253)

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Quantitative analysis of phospholipids by 31P-NMR.

open access: yesJournal of Lipid Research, 1988
High-field 31P nuclear magnetic resonance spectroscopy was used to quantitate phospholipids in mixtures in organic solvents. The sample is dissolved in chloroform-methanol and analyzed at 161.7 MHz with decoupling of the protons.
N Sotirhos, B Herslöf, L Kenne
doaj   +1 more source

MALDI-TOF MS with a Matrix of 3, 4-diaminobenzophenone for the Analysis of Phospholipids

open access: yes, 2009
Lipids and phospholipids are very important biomolecules except proteins, carbohydrates and nucleic acids[1]. Phospholipids have also been proved to be specific cancer biomarkers[2].
苗楠, 邹汉法, 潘陈松, 周厚江
core  

Computational modelling of phospholipids in plasma membranes [PDF]

open access: yes, 2022
The purpose of this project was to investigate if the constituents of phospholipids in plasma membranes affect how cells interact with graphene (G) and graphene oxide (GO).
Lanai, Victor
core  

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

open access: yesAdvanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

Phospholipids in biotechnologies

open access: yesТонкие химические технологии, 2009
The review describes modern concepts of chemical and enzymatic synthesis, isolation of substances from natural sources, and creation of industrial technologies for obtaining phospholipids of various molecular types.
V. I. Shvets
doaj  

Correlation Between Lipid Profile of Sperm Cells and Seminal Plasma With Lipid Profile of Serum in Infertile Men

open access: yesAvicenna Journal of Medical Biochemistry, 2014
Background Lipids play an important role in the functional activity of sperm cells. Objectives The main goal of this study was to assess the correlation between the levels of cholesterol, phospholipids and ...
Tavilani   +5 more
doaj   +1 more source

Connexin channels and phospholipids: association and modulation

open access: yesBMC Biology, 2009
Background For membrane proteins, lipids provide a structural framework and means to modulate function. Paired connexin hemichannels form the intercellular channels that compose gap junction plaques while unpaired hemichannels have regulated functions in
Harris Andrew L, Locke Darren
doaj   +1 more source

Phospholipids at multicorer station M27/2_MC471

open access: yes, 1999
Phospholipids at multicorer station M27 ...
Boetius, Antje   +9 more
core   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

open access: yesAdvanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia   +10 more
wiley   +1 more source

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