Results 21 to 30 of about 87,699 (269)

Inhibition of eIF2α Phosphorylation by Peste des Petits Ruminant Virus Phosphoprotein Facilitates Viral Replication

Frontiers in Veterinary Science, 2021
Peste des petits ruminant virus (PPRV) causes a highly contagious disease in small ruminants. The molecular mechanism of PPRV replication and its interactions with hosts are poorly studied.
Niyokwishimira Alfred, Niyokwishimira Alfred, Bang Qian, Xiaodong Qin, Xiangping Yin, Meera Prajapati, Meera Prajapati, Yongxi Dou, Yanmin Li, Zhidong Zhang   +9 more
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Phosphorylation-Mediated Molecular Pathway Changes in Human Pituitary Neuroendocrine Tumors Identified by Quantitative Phosphoproteomics

Cells, 2021
To investigate the biological role of protein phosphorylation in human nonfunctional pituitary neuroendocrine tumors (NF-PitNETs), proteins extracted from NF-PitNET and control tissues were analyzed with tandem mass tag (TMT)-based quantitative ...
Jiajia Li, Siqi Wen, Biao Li, Na Li, Xianquan Zhan   +4 more
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Interactions between the Nucleoprotein and the Phosphoprotein of Pneumoviruses: Structural Insight for Rational Design of Antivirals

Viruses, 2021
Pneumoviruses include pathogenic human and animal viruses, the most known and studied being the human respiratory syncytial virus (hRSV) and the metapneumovirus (hMPV), which are the major cause of severe acute respiratory tract illness in young children
Hortense Decool, Lorène Gonnin, Irina Gutsche, Christina Sizun, Jean-François Eléouët, Marie Galloux   +5 more
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A Structural and Dynamic Analysis of the Partially Disordered Polymerase-Binding Domain in RSV Phosphoprotein

Biomolecules, 2021
The phosphoprotein P of Mononegavirales (MNV) is an essential co-factor of the viral RNA polymerase L. Its prime function is to recruit L to the ribonucleocapsid composed of the viral genome encapsidated by the nucleoprotein N.
Christophe Cardone, Claire-Marie Caseau, Benjamin Bardiaux, Aurélien Thureaux, Marie Galloux, Monika Bajorek, Jean-François Eléouët, Marc Litaudon, François Bontems, Christina Sizun   +9 more
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Phosphoprotein Detection in Sweat Realized by Intercalation Structure 2D@3D g-C₃N₄@Fe₃O₄ Wearable Sensitive Motif

Biosensors, 2022
Abnormal protein phosphorylation in sweat metabolites is closely related to cancer, cardiovascular disease, and other diseases. The real-time monitoring of phosphoproteins in sweat is significant for early monitoring of disease biomarkers.
Yuting Qiao, Lijuan Qiao, Peize Zhao, Peng Zhang, Fanbin Wu, Jiahui Zhang, Li Gao, Bingxin Liu, Lei Zhang   +8 more
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Rabies Virus Exploits Cytoskeleton Network to Cause Early Disease Progression and Cellular Dysfunction

Frontiers in Veterinary Science, 2022
Rabies virus (RABV) is a cunning neurotropic pathogen and causes top priority neglected tropical diseases in the developing world. The genome of RABV consists of nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G), and RNA ...
Xilin Liu, Zeeshan Nawaz, Caixia Guo, Sultan Ali, Muhammad Ahsan Naeem, Tariq Jamil, Waqas Ahmad, Muhammad Usman Siddiq, Sarfraz Ahmed, Muhammad Asif Idrees, Ali Ahmad   +10 more
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Avian Metapneumovirus Subgroup C Phosphoprotein Suppresses Type I Interferon Production by Blocking Interferon Regulatory Factor 3 Nuclear Translocation

Microbiology Spectrum, 2023
Avian metapneumovirus subgroup C (aMPV/C) is an important pathogen that causes upper respiratory symptoms and egg production decline in turkeys and chickens. aMPV/C infection leads to inhibition of the host antiviral immune response.
Lei Hou, Yongyan Shi, Jinshuo Guo, Tong Sun, Dedong Wang, Xiaoyu Yang, Changzhe Liu, Yongqiu Cui, Ning Zhu, Xinxin Tong, Yang Pan, Xufei Feng, Jianwei Zhou, Jue Liu   +13 more
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Structural Biology of Calcium Phosphate Nanoclusters Sequestered by Phosphoproteins

Crystals, 2020
Biofluids that contain stable calcium phosphate nanoclusters sequestered by phosphopeptides make it possible for soft and hard tissues to co-exist in the same organism with relative ease. The stability diagram of a solution of nanocluster complexes shows
Samuel Lenton, Qian Wang, Tommy Nylander, Susana Teixeira, Carl Holt   +4 more
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Quantitative Phosphoproteomic Analysis Provides Insights into the Sodium Bicarbonate Responsiveness of Glycine max

Biomolecules, 2023
Sodium bicarbonate stress caused by NaHCO3 is one of the most severe abiotic stresses affecting agricultural production worldwide. However, little attention has been given to the molecular mechanisms underlying plant responses to sodium bicarbonate ...
Qiang Li, Minglong Li, Huiying Ma, Man Xue, Tong Chen, Xiaodong Ding, Shuzhen Zhang, Jialei Xiao   +7 more
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Structure and Dynamics of the Unassembled Nucleoprotein of Rabies Virus in Complex with Its Phosphoprotein Chaperone Module

Viruses, 2022
As for all non-segmented negative RNA viruses, rabies virus has its genome packaged in a linear assembly of nucleoprotein (N), named nucleocapsid. The formation of new nucleocapsids during virus replication in cells requires the production of soluble N ...
Francine C. A. Gérard, Jean-Marie Bourhis, Caroline Mas, Anaïs Branchard, Duc Duy Vu, Sylvia Varhoshkova, Cédric Leyrat, Marc Jamin   +7 more
doaj   +1 more source