Results 31 to 40 of about 91,004 (275)

Structural Determination of the Australian Bat Lyssavirus Nucleoprotein and Phosphoprotein Complex

open access: yesViruses, 2023
Australian bat lyssavirus (ABLV) shows similar clinical symptoms as rabies, but there are currently no protein structures available for ABLV proteins. In lyssaviruses, the interaction between nucleoprotein (N) and phosphoprotein (N) in the absence of RNA
Camilla M. Donnelly   +4 more
doaj   +1 more source

SPP1 (secreted phosphoprotein 1) [PDF]

open access: yes, 2008
Review on SPP1 (secreted phosphoprotein 1), with data on DNA, on the protein encoded, and where the gene is ...
Rodrigues, LR   +2 more
core   +1 more source

The Nucleocapsid of Paramyxoviruses: Structure and Function of an Encapsidated Template

open access: yesViruses, 2021
Viruses of the Paramyxoviridae family share a common and complex molecular machinery for transcribing and replicating their genomes. Their non-segmented, negative-strand RNA genome is encased in a tight homopolymer of viral nucleoproteins (N).
Louis-Marie Bloyet
doaj   +1 more source

Caged Phosphoproteins

open access: yesJournal of the American Chemical Society, 2004
We present the chemical and biological synthesis of caged phosphoproteins using the in vitro nonsense codon suppression methodology. Specifically, phosphoamino acid analogues of serine, threonine, and tyrosine with a single photocleavable o-nitrophenylethyl caging group were synthesized as the amino acyl tRNA adducts for insertion into full-length ...
Rothman, Deborah M.   +5 more
openaire   +3 more sources

Heatmap of hierarchically clustered signaling phosphoprotein levels.

open access: yes, 2022
Columns are individual samples and rows are cellular phosphoprotein features as labelled. Values are hierarchically clustered on columns and rows. Color values are normalized to row min-max.
Michael P. Kelly (9145503)   +12 more
core   +1 more source

PEA15 (phosphoprotein enriched in astrocytes 15) [PDF]

open access: yes, 2012
Review on PEA15 (phosphoprotein enriched in astrocytes 15), with data on DNA, on the protein encoded, and where the gene is ...
Bartholomeusz, C, Lee, J, Ueno, NT
core   +1 more source

Rab11-FIP3 is a cell cycle-regulated phosphoprotein [PDF]

open access: yes, 2012
<b>BACKGROUND:</b> Rab11 and its effector molecule, Rab11-FIP3 (FIP3), associate with recycling endosomes and traffic into the furrow and midbody of cells during cytokinesis.
Xinzi Yu   +49 more
core   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode   +16 more
wiley   +1 more source

Proteogenomic characterization of cholangiocarcinoma

open access: yesHepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng   +18 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

open access: yesHepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli   +13 more
wiley   +1 more source

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