Results 31 to 40 of about 9,926 (149)

Phosphoinositides in the Hepatitis C Virus Life Cycle

Viruses, 2012
Eukaryotes possess seven different phosphoinositides (PIPs) that help form the unique signatures of various intracellular membranes. PIPs serve as docking sites for the recruitment of specific proteins to mediate membrane alterations and integrate ...
Aleem Siddiqui, Bryan Bishé, Gulam Syed
doaj   +1 more source

Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21.

PLoS ONE, 2012
Metazoan mitosis requires remodelling of sub-cellular structures to ensure proper division of cellular and genetic material. Faults often lead to genomic instability, cell cycle arrests and disease onset.
Veerle De Wever, David C Lloyd, Isha Nasa, Mhairi Nimick, Laura Trinkle-Mulcahy, Robert Gourlay, Nick Morrice, Greg B G Moorhead   +7 more
doaj   +1 more source

Phosphoprotein Phosphatase Activity in the Thyroid

Experimental Biology and Medicine, 1975
Phosphoprotein phosphatase activity in the calf thyroid was found in various subcellular fractions. The relative amount in each fraction varied according to the substrate used: The 500g fraction had the highest specific activity when protamine was used, while the 5000g fraction was highest when histone was used. Triton X-100 tended to increase activity
S W, Spaulding, G N, Burrow
openaire   +2 more sources

Pervasive phenotypic effects of FBXO42 are promoted by regulation of PP4 phosphatase

The EMBO Journal
F-box proteins are the substrate recognition modules of the SCF (SKP1–Cullin–F-box) E3 ubiquitin ligase complex. FBXO42, an understudied member of this family, has recently emerged as a modulator of key cellular processes, including cell cycle ...
Hongbin Yang, Paul Smith, Yingying Ma, Emily Southworth, Varun Gopala Krishna, Beatrice Salerno, Joseph Rowland, Alexander E P Loftus, Domenico Grieco, Iolanda Vendrell, Roman Fischer, Benedikt M Kessler, Vincenzo D’Angiolella   +12 more
doaj   +1 more source

Quantitative in vivo phosphoproteomics reveals reversible signaling processes during nitrogen starvation and recovery in the biofuel model organism Chlamydomonas reinhardtii

Biotechnology for Biofuels, 2017
Background Nitrogen deprivation and replenishment induces massive changes at the physiological and molecular level in the green alga Chlamydomonas reinhardtii, including reversible starch and lipid accumulation.
Valentin Roustan, Shiva Bakhtiari, Pierre-Jean Roustan, Wolfram Weckwerth   +3 more
doaj   +1 more source

Transient calcium and dopamine increase PKA activity and DARPP-32 phosphorylation.

PLoS Computational Biology, 2006
Reinforcement learning theorizes that strengthening of synaptic connections in medium spiny neurons of the striatum occurs when glutamatergic input (from cortex) and dopaminergic input (from substantia nigra) are received simultaneously.
Maria Lindskog, MyungSook Kim, Martin A Wikström, Kim T Blackwell, Jeanette Hellgren Kotaleski   +4 more
doaj   +1 more source

SUMOylation of protein phosphatase 5 regulates phosphatase activity and substrate release

EMBO Reports
The serine/threonine protein phosphatase 5 (PP5) regulates hormone and stress-induced signaling networks. Unlike other phosphoprotein phosphatases, PP5 contains both regulatory and catalytic domains and is further regulated through post-translational ...
Rebecca A Sager, Sarah J Backe, Diana M Dunn, Jennifer A Heritz, Elham Ahanin, Natela Dushukyan, Barry Panaretou, Gennady Bratslavsky, Mark R Woodford, Dimitra Bourboulia, Mehdi Mollapour   +10 more
doaj   +1 more source

A Mass Spectrometry-Based Approach to Identify Phosphoprotein Phosphatases and their Interactors. [PDF]

J Vis Exp, 2022
Smolen KA, Kettenbach AN.
europepmc   +1 more source

Affinity-based profiling of endogenous phosphoprotein phosphatases by mass spectrometry. [PDF]

Nat Protoc, 2021
Brauer BL, Wiredu K, Mitchell S, Moorhead GB, Gerber SA, Kettenbach AN.   +5 more
europepmc   +1 more source

The role of phosphoprotein phosphatases catalytic subunit genes in pancreatic cancer. [PDF]

Biosci Rep, 2021
Hang J, Lau SY, Yin R, Zhu L, Zhou S, Yuan X, Wu L.   +6 more
europepmc   +1 more source