Results 131 to 140 of about 73,329 (379)

Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells.

open access: yesPLoS ONE, 2010
The proteasome inhibitor bortezomib represents an important advance in the treatment of multiple myeloma (MM). Bortezomib inhibits the activity of the 26S proteasome and induces cell death in a variety of tumor cells; however, the mechanism of ...
Feng Ge   +9 more
doaj   +1 more source

Peer Review #3 of "Identification and molecular characterization of mutations in nucleocapsid phosphoprotein of SARS-CoV-2 (v0.1)"

open access: gold, 2021
Gajendra Kumar   +99 more
openalex   +2 more sources

Cardamonin Commands the Colonic Metabolite Columbianetin Acetate to Compete Against LPS in Binding HMGB1 in the Kidney, Preventing Lipopolysaccharide‐Induced Renal Tubular Pyroptosis

open access: yesFood Frontiers, EarlyView.
Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou   +6 more
wiley   +1 more source

The B56 Family of Protein Phosphatase 2A (PP2A) Regulatory Subunits Encodes Differentiation-induced Phosphoproteins That Target PP2A to Both Nucleus and Cytoplasm*

open access: yesJournal of Biological Chemistry, 1996
Protein phosphatase 2A is a heterotrimeric protein serine/threonine phosphatase consisting of a 36-kDa catalytic C subunit, a 65-kDa structural A subunit, and a variable regulatory B subunit.
B. McCright   +3 more
semanticscholar   +1 more source

Multisite phosphorylation of Pin1-associated mitotic phosphoproteins revealed by monoclonal antibodies MPM-2 and CC-3

open access: yesBMC Cell Biology, 2004
Background The peptidyl-prolyl isomerase Pin1 recently revealed itself as a new player in the regulation of protein function by phosphorylation. Pin1 isomerizes the peptide bond of specific phosphorylated serine or threonine residues preceding proline in
Vincent Michel   +2 more
doaj   +1 more source

4E-BP1Thr46 Phosphorylation Association with Poor Prognosis in Quantitative Phosphoproteomics of Portal Vein Tumor Thrombus Revealed that 4E-BP1Thr46 Phosphorylation is Associated with Poor Prognosis in HCC

open access: yesCancer Management and Research, 2020
Xincong Lin,1,2,* Yao Huang,1,2,* Ying Sun,2 Xionghong Tan,2 Jiahe Ouyang,2 Bixing Zhao,2 Yingchao Wang,2 Xiaohua Xing,1,2 Jingfeng Liu1,2 1The First Affiliated Hospital of Fujian Medical University, Fuzhou 350007, People’s Republic of China; 2The United
Lin X   +8 more
doaj  

Reduced Dietary Protein Induces Changes in the Dental Proteome

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs   +2 more
wiley   +1 more source

Serum Fetuin A and Secreted Phosphoprotein 24 as Diagnostic Markers in Inflammatory Bowel Disease

open access: diamond, 2020
İnanç Karakoyun   +7 more
openalex   +2 more sources

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