Results 121 to 130 of about 37,055 (269)

Protein phosphorylation networks in Baylisascaris procyonis revealed by phosphoproteomic analysis

Parasites & Vectors
Background Baylisascaris procyonis is an intestinal ascarid worm that parasitizes in raccoons and causes fatal neural, visceral, and ocular larva migrans in humans.
Qin Meng, Zhikang Li, Qiguan Qiu, Shuyu Chen, Haiyan Gong, Xiaoruo Tan, Xiaoheng Liu, Zhaoguo Chen, Wei Liu   +8 more
doaj   +1 more source

The top 20 phosphoproteins experiencing changes in phosphorylation in the PRL-3 overexpressing cells.

, 2017
The top 20 phosphoproteins experiencing changes in phosphorylation in the PRL-3 overexpressing cells.
Chengchao Shou (111936), Shenyi Lian (3625817), Yongyong Yang (3625820), Like Qu (111934), Lin Meng (147025)   +4 more
core   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Ribosomal phosphoproteins in Microsporum canis

, 1988
Ribosomal phosphoproteins of Microsporum canis labelled in vivo were characterised by two-dimensional and SDS polyacrylamide gel electrophoresis. A small subunit protein, S6, was the only phosphoprotein identified in 40S and 80S in basic-acidic two ...
Mandiyan, Valsan
core  

Functional classifications (A) and protein subcellular locations (B) of all 1020 phosphoproteins.

, 2014
Functional classifications (A) and protein subcellular locations (B) of all 1020 phosphoproteins.
Yanyan Meng (548852), Changhui Feng (548855), Shengxi Zhang (548856), Shuli Fan (121199), Hengling Wei (121188), Chaoyou Pang (121192), Xianjin Zhan (548853), Ji Liu (110659), Meizhen Song (121190), Jiayang Lan (548854), Shuxun Yu (89036)   +10 more
core   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Keeping It Native: Non‐Denaturing Approaches to Top‐Down Protein Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics and top‐down mass spectrometry approaches provide direct characterization of proteoforms; the specific molecular forms of proteins, including post‐translational modifications, truncations, alternative splicing, and sequence variants.
Michael Xiao, Edvaldo Vasconcelos Soares Maciel, Frederik Lermyte, Owen S. Skinner   +3 more
wiley   +1 more source

Iron-chelated thermoresponsive polymer brushes on bismuth titanate nanosheets for metal affinity separation of phosphoproteins

, 2020
Separation of phosphoproteins plays an important role for identification of biomarkers in life science. In this work, bismuth titanate supported, iron-chelated thermoresponsive polymer brushes were prepared for selective separation of phosphoproteins ...
Zheng, Hong Wei,, Chen, Ming Li,, Wang, Jian Hua, Ye, Lei,, Guo, Peng Fei,, Guo, Peng Fei, Gong, Hai Yue,, Wang, Jian Hua,, Ye, Lei, Gong, Hai Yue, Zheng, Hong Wei, Chen, Ming Li, Lund University.   +12 more
core   +1 more source

Current status and future perspectives of platelet function‐guided precision antiplatelet therapy for patients with cerebral infarction

Neuroprotection, EarlyView.
Antiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Guoliang Zhu, Xiaoling Chen, Xinyi Huang, Quandan Tan, Qing Cao, Yali Yang, Yapeng Lin, Jie Yang   +7 more
wiley   +1 more source

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

Neuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang, Linjie Wei, Mingxi Li, Bo Wu, Rongjian Ouyang, Gang Zhu, Yujie Chen   +6 more
wiley   +1 more source