Results 131 to 140 of about 37,055 (269)

Differentially abundant phosphoproteins in the Longissimus lumborum muscle of Angus and Nellore bulls.

open access: yes, 2017
Differentially abundant phosphoproteins in the Longissimus lumborum muscle of Angus and Nellore bulls.
Edvaldo Barros (3684544)   +8 more
core   +1 more source

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca   +7 more
wiley   +1 more source

Proteomic Analysis of Phosphoproteins in the Rice Nucleus During the Early Stage of Seed Germination

open access: yes, 2015
The early stage of seed germination is the first step in the plant life cycle without visible morphological change. To investigate the mechanism controlling the early stage of rice seed germination, we performed gel-and label-free nuclear ...
Setsuko Komatsu (422175)   +4 more
core   +1 more source

Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf   +8 more
wiley   +1 more source

Phosphoproteins and the Dawn of Functional Phenotyping

open access: yes, 2011
Phosphorylation is one of the most important processes in cell signal transduction. Detection of phosphorylated proteins in cancer tissue is useful for prognosis and diagnosis, and it might be very helpful in monitoring treatment using targeted therapy ...
E.D. Hsi, J. Bodo
core   +1 more source

Optical Control of Therapeutic Synthetic Cells: Controlling Biomolecule Synthesis, Activation, and Communication

open access: yesSmall Methods, EarlyView.
Combining synthetic cells engineering, cell‐free expression, and optical regulation may enable a new generation of programmable synthetic cell platforms. By providing spatiotemporal control over biomolecule synthesis, activation, transport, release, and communication, light offers a versatile strategy for coordinating proteins, RNAs, peptides, and ...
Gia Bao Leon Hoang, Taniya Chakraborty
wiley   +1 more source

Thylakoid Phosphoproteins: Identification of Phosphorylation Sites

open access: yes, 2010
Redox-dependent thylakoid protein phosphorylation regulates both the short- and long-term acclimation of the photosynthetic apparatus to changes in environmental conditions. The major thylakoid phosphoproteins belong to photosystem II (D1, D2, CP43, PsbH)
Alexander V. Vener   +5 more
core   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li   +12 more
wiley   +1 more source

Changes of Microbial and Component Composition of Giraffe Milk During Mid‐ to Late Lactation

open access: yesZoo Biology, EarlyView.
Giraffe milk – graphical abstract text, Giraffe: late lactation milk, Involution at approximately 15 months of lactation, Content of saccharides and fat decrease, Protein content increases, Content of minerals increase, Microbiological quality high ABSTRACT The proximate, mineral and microbiological composition of milk from five giraffes from mid ...
G. Osthoff   +4 more
wiley   +1 more source

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