Results 131 to 140 of about 31,335 (237)

Divergent AKT Signalling Mechanisms Regulate GLUT4 Translocation and Glucose Uptake in Skeletal Muscle and Adipose Tissue

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background The serine/threonine kinase AKT is a key regulator of glucose and energy metabolism. Prevailing dogma suggests that AKT is an obligate intermediate for glucose uptake in all metabolic tissues and that impaired AKT signalling is a major molecular driver of insulin resistance in obesity.
Natasha Jaiswal   +5 more
wiley   +1 more source

Cross-Species Analysis of ABA-Induced Phosphosignaling Landscapes in Rice, Soybean, and Arabidopsis. [PDF]

open access: yesProteomes
Takase H   +8 more
europepmc   +1 more source

Proteomic and Phosphoproteomic Characteristics of Multiple Brain Regions in Rhesus Macaques After SARS‐CoV‐2 Infection

open access: yesMedComm, Volume 7, Issue 8, August 2026.
The study found that SARS‐CoV‐2 Omicron infection causes region‐specific inflammatory, immune, synaptic, and signaling disorders in the brain, and the predicted kinases and differentially expressed proteins may serve as potential targets for COVID‐19‐related drug discovery.
Qiaochu Wang   +8 more
wiley   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, Volume 26, Issue 8, Page 29-40, August 2026.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

open access: yesPROTEOMICS, Volume 26, Issue 8, Page 69-80, August 2026.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim   +4 more
wiley   +1 more source

Exploring the Phosphoregulatory Network of Human Sucrose Non-Fermenting 1-Related Kinase. [PDF]

open access: yesBiology (Basel)
Gopalakrishnan V   +6 more
europepmc   +1 more source

Cementum Attachment Protein‐Derived Peptides Modulate Brushite and Calcium Oxalate Crystallization In Vitro

open access: yesJournal of Peptide Science, Volume 32, Issue 8, August 2026.
Cementum attachment protein‐derived peptides adsorb to specific crystallographic faces of brushite and calcium oxalate, blocking calcium deposition. This phosphorylation‐enhanced modulation alters crystal growth under conditions in vitro, leading to the formation of irregular brushite crystals and rosette‐like calcium oxalate morphologies.
Alberto Mimila‐Cortes   +9 more
wiley   +1 more source

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