Results 111 to 120 of about 37,055 (269)

Majorbio Cloud 2026 Update: An End‐to‐End Solution for Proteomics Research

open access: yesiMetaMed, EarlyView.
The recent upgrade of Majorbio Cloud facilitates a more streamlined and accurate research process, aiding researchers across the various proteomics subfields. Furthermore, it propels the advancement of multi‐layered, multi‐omics scientific investigations centered around proteins.
Caiping Shi   +17 more
wiley   +1 more source

Global landscape of protein phosphorylation during plant regeneration initiation in cotton (Gossypium hirsutum L.)

open access: yesBMC Biology
Background Phosphorylation is one of the most common post-translational modifications and is central to many cellular signaling events; however, little is currently known about the phosphorylation landscape during somatic embryogenesis (SE) for plant ...
Huihui Guo   +11 more
doaj   +1 more source

Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells.

open access: yesPLoS ONE, 2010
The proteasome inhibitor bortezomib represents an important advance in the treatment of multiple myeloma (MM). Bortezomib inhibits the activity of the 26S proteasome and induces cell death in a variety of tumor cells; however, the mechanism of ...
Feng Ge   +9 more
doaj   +1 more source

Functional classifications (A) and protein subcellular locations (B) of the 167 phosphoproteins.

open access: yes, 2014
Functional classifications (A) and protein subcellular locations (B) of the 167 phosphoproteins.
Yanyan Meng (548852)   +10 more
core   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

open access: yesInterdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu   +6 more
wiley   +1 more source

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

open access: yesInterdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang   +8 more
wiley   +1 more source

4E-BP1Thr46 Phosphorylation Association with Poor Prognosis in Quantitative Phosphoproteomics of Portal Vein Tumor Thrombus Revealed that 4E-BP1Thr46 Phosphorylation is Associated with Poor Prognosis in HCC

open access: yesCancer Management and Research, 2020
Xincong Lin,1,2,* Yao Huang,1,2,* Ying Sun,2 Xionghong Tan,2 Jiahe Ouyang,2 Bixing Zhao,2 Yingchao Wang,2 Xiaohua Xing,1,2 Jingfeng Liu1,2 1The First Affiliated Hospital of Fujian Medical University, Fuzhou 350007, People’s Republic of China; 2The United
Lin X   +8 more
doaj  

Multisite phosphorylation of Pin1-associated mitotic phosphoproteins revealed by monoclonal antibodies MPM-2 and CC-3

open access: yesBMC Cell Biology, 2004
Background The peptidyl-prolyl isomerase Pin1 recently revealed itself as a new player in the regulation of protein function by phosphorylation. Pin1 isomerizes the peptide bond of specific phosphorylated serine or threonine residues preceding proline in
Vincent Michel   +2 more
doaj   +1 more source

Expression of phosphoproteins and amelotin in teeth

open access: yes, 2007
The organic material of our teeth consists of collagens and a number of calcium-binding phosphoproteins. Six of these phosphoproteins have recently been grouped in the family of the SIBLINGs (small integrin-binding ligand, N-linked glycoproteins), namely
Taeschler, Sara   +7 more
core  

Composite Inflammatory Score for Predicting Progression‐Free Survival in Metastatic Clear Cell Renal Cell Carcinoma Treated With First‐Line Toripalimab Plus Axitinib

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Routine inflammatory and nutritional markers may help stratify progression risk in metastatic clear cell renal cell carcinoma during immunotherapy‐based treatment. This single‐center retrospective study included 237 patients who received first‐line toripalimab plus axitinib therapy.
Yun‐Feng Wu   +4 more
wiley   +1 more source

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