Results 91 to 100 of about 36,892 (294)
Bemnifosbuvir (BEM) and ruzasvir (RZR) are pan‐genotypic HCV polymerase (NS5B) and NS5A inhibitors, respectively. In a single‐arm study (NCT05904470), 215 treatment‐naïve, adherent participants with chronic HCV (with or without cirrhosis) received BEM 550 mg QD plus RZR 180 mg QD for 8 weeks.
Carolin Zitzmann +4 more
wiley +1 more source
We used tandem mass tag proteomics to explore and compare phosphoprotein profiles and the mechanisms underlying protein phosphorylation regulation in cattle-yak longissimus thoracis (CYLT) and yak longissimus thoracis (YLT).
Xinping Chang +5 more
doaj +1 more source
Biosynthesis of O-phosphoserine-containing phosphoproteins by isolated bone cells of mouse calvaria [PDF]
Five groups of isolated bone cells from mouse calvaria were incubated with [3H]serine and the presence and amount of O[3H]phosphoserine used as an indication of phosphoprotein synthesis.
Sakamoto, M. +7 more
core +1 more source
Abstract Background Dentitions have diversified enormously during vertebrate evolution, involving reductions, modifications, or allocations to prey seizing and processing regions. A combination of ancient and novel features related to dental and oropharyngeal apparatuses is found in extant lineages of non‐teleost fishes, such as the gars.
Anna Pospisilova +4 more
wiley +1 more source
Protein phosphorylation in sweat metabolites plays a key role in nerve activity, muscle contraction, and other activities, and abnormal protein phosphorylation may lead to diseases such as neurodegenerative disorders. Real-time non-invasive monitoring of
Ce Bian +7 more
doaj +1 more source
Ribosomal phosphoproteins in Microsporum canis
Ribosomal phosphoproteins of Microsporum canis labelled in vivo were characterised by two-dimensional and SDS polyacrylamide gel electrophoresis. A small subunit protein, S6, was the only phosphoprotein identified in 40S and 80S in basic-acidic two ...
Mandiyan, Valsan
core
A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble +2 more
wiley +1 more source
Protein kinases associated with the yeast phosphoproteome
Background Protein phosphorylation is an extremely important mechanism of cellular regulation. A large-scale study of phosphoproteins in a whole-cell lysate of Saccharomyces cerevisiae has previously identified 383 phosphorylation sites in 216 peptide ...
Munn Alan L +2 more
doaj +1 more source
Proteomic signatures of equine dental tooth tissues in ageing and disease
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen +8 more
wiley +1 more source
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor +7 more
wiley +1 more source

