Results 151 to 160 of about 20,110 (245)
Food Frontiers, Volume 7, Issue 2, March 2026.Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li +8 more
wiley +1 more source
Journal of Intelligent Medicine, Volume 3, Issue 1, Page 26-46, March 2026.Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan +3 more
wiley +1 more source
Analyzing peptides and proteins by mass spectrometry: principles and applications in proteomics [PDF]
, 2012 Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166The study of proteins has been a key element in biomedicine and biotechnology because of their important role in cell functions or enzymatic activity. Cells are the basic unit of living
Estanyol i Ullate, Josep Maria +3 more
core +1 more source
LKB1–AMPK Signaling Pathway in Cardiovascular and Other Diseases
MedComm, Volume 7, Issue 3, March 2026.The LKB1–AMPK pathway has a central regulatory role in various diseases. Dysfunction of this pathway can lead to pathological processes in cardiovascular diseases (atrial fibrillation, myocardial infarction, myocardial hypertrophy, atherosclerosis), metabolic diseases (diabetes and kidney disease), neurodegenerative diseases (Alzheimer's disease ...
Zhuo Chen, Qin Yang, Guo‐Wei He
wiley +1 more source
Magnesium Deficiency Accelerates Gut Aging and Increases Susceptibility to Colitis
Aging Cell, Volume 25, Issue 3, March 2026.Aging is associated with a gut‐specific decline in magnesium (Mg), which accelerates intestinal aging and aggravates colitis in aged mice. Mechanistically, Mg deficiency reshapes the phosphoproteome and N‐glycoproteome, destabilizing adhesion complexes.
Rou Zhang +16 more
wiley +1 more source
Sex Differences in Metabolite–Immune Circuits of Neuroinflammation
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Sex is a fundamental yet underexplored determinant of human neuroinflammation. Across autoimmune, neurodegenerative, and post‐infectious neurological syndromes, males and females exhibit consistent differences in disease vulnerability, progression, and immune tone.
Priyanka Saminathan +6 more
wiley +1 more source
Journal of Neuroendocrinology, Volume 38, Issue 3, March 2026.Abstract Nonfunctioning pituitary adenomas (NFPAs) are common intracranial tumors that, despite being histologically benign, can exhibit invasive growth, as well as postoperative tumor progression. Surgical resection is the primary treatment of choice; however, residual tumor tissue is frequently observed, with between 30% and 50% of these cases ...
Thomas Skoglund +5 more
wiley +1 more source
Molecular Plant Pathology, Volume 27, Issue 3, March 2026.The coiled‐coil domain functions as the core signalling module of wheat NLRMoro, with residues 62–116 forming a minimal active region whose activity is fine‐tuned by intramolecular NBS and LRR regulation and key control sites. ABSTRACT Nucleotide‐binding site (NBS) leucine‐rich repeat (LRR) receptors (NLRs) are crucial for plant immunity but often come
Xiaoxu Zhu +14 more
wiley +1 more source
Pho-Tip: One-Pot Dephosphorylation for Rapid and Sensitive Analysis of DIA Phosphoproteomics Data. [PDF]
Anal ChemFaisst KD +4 more
europepmc +1 more source