Results 21 to 30 of about 2,736 (189)

A pilot study of the dynamics of tissue oxygenation in vivo using time-resolved phosphorescence imaging

open access: yesJournal of Innovative Optical Health Sciences, 2021
Oxygenation of tissues plays an important role in the development and progression of tumor to treatment effects. Method of metalloporphyrines phosphorescence quenching by oxygen is one of the ways to measure dynamics of the oxygen concentration in the ...
Natalia Kazachkina   +3 more
doaj   +1 more source

Photon counting phosphorescence lifetime imaging with TimepixCam [PDF]

open access: yesReview of Scientific Instruments, 2017
TimepixCam is a novel fast optical imager based on an optimized silicon pixel sensor with a thin entrance window and read out by a Timepix Application Specific Integrated Circuit. The 256 × 256 pixel sensor has a time resolution of 15 ns at a sustained frame rate of 10 Hz. We used this sensor in combination with an image intensifier for wide-field time-
Liisa M. Hirvonen   +3 more
openaire   +4 more sources

Biocompatible Phosphorescent O2 Sensors Based on Ir(III) Complexes for In Vivo Hypoxia Imaging

open access: yesBiosensors, 2023
In this work, we obtained three new phosphorescent iridium complexes (Ir1–Ir3) of general stoichiometry [Ir(N^C)2(N^N)]Cl decorated with oligo(ethylene glycol) fragments to make them water-soluble and biocompatible, as well as to protect them from ...
Mozhgan Samandarsangari   +6 more
doaj   +1 more source

Phosphorescent O2-Probes Based on Ir(III) Complexes for Bioimaging Applications

open access: yesChemosensors, 2023
The design, synthesis, and investigation of new molecular oxygen probes for bioimaging, based on phosphorescent transition metal complexes are among the topical problems of modern chemistry and advanced bioimaging.
Mozhgan Samandarsangari   +5 more
doaj   +1 more source

Measurement of cerebral oxygen pressure in living mice by two-photon phosphorescence lifetime microscopy

open access: yesSTAR Protocols, 2022
Summary: The ability to quantify partial pressure of oxygen (pO2) is of primary importance for studies of metabolic processes in health and disease. Here, we present a protocol for imaging of oxygen distributions in tissue and vasculature of the cerebral
Eva Erlebach   +6 more
doaj   +1 more source

Luminescent probes for luminescence lifetime sensing and imaging in live cells: a narrative review

open access: yesJournal of Bio-X Research, 2020
. Luminescence (mostly fluorescence and phosphorescence) probes are a powerful tool widely used in the life sciences research. They can be used, for example, in the quantitative analysis of physiological parameters, visualization of different cell ...
Kaixuan Nie   +4 more
doaj   +1 more source

High resolution imaging of intracellular oxygen concentration by phosphorescence lifetime [PDF]

open access: yesScientific Reports, 2015
AbstractOptical methods using phosphorescence quenching by oxygen are suitable for sequential monitoring and non-invasive measurements for oxygen concentration (OC) imaging within cells. Phosphorescence intensity measurement is widely used with phosphorescent dyes. These dyes are ubiquitously but heterogeneously distributed inside the whole cell.
Hiromi Kurokawa   +10 more
openaire   +2 more sources

Functionalizing Collagen with Vessel‐Penetrating Two‐Photon Phosphorescence Probes: A New In Vivo Strategy to Map Oxygen Concentration in Tumor Microenvironment and Tissue Ischemia

open access: yesAdvanced Science, 2021
The encapsulation and/or surface modification can stabilize and protect the phosphorescence bio‐probes but impede their intravenous delivery across biological barriers.
Cheng‐Ham Wu   +16 more
doaj   +1 more source

Red Light-Emitting Water-Soluble Luminescent Iridium-Containing Polynorbornenes: Synthesis, Characterization and Oxygen Sensing Properties in Biological Tissues In Vivo

open access: yesMolecules, 2021
New water-soluble polynorbornenes P1–P4 containing oligoether, amino acid groups and luminophoric complexes of iridium(III) were synthesized by ring-opening metathesis polymerization.
Leonid N. Bochkarev   +11 more
doaj   +1 more source

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