The nucleobase analog 4-thiouracil hijacks the pyrimidine salvage pathway to inhibit <i>Staphylococcus aureus</i> growth. [PDF]
Munneke MJ, Freiberg JA, Skaar EP.
europepmc +1 more source
Nicotinamide phosphoribosyltransferase (NAMPT) [PDF]
openaire +1 more source
Structural and kinetic analysis of distinct active and inactive states of Burkholderia cenocepacia orotate phosphoribosyltransferase. [PDF]
Sharma N +16 more
europepmc +1 more source
Epigenetic modulation of human neurobiological disorders: Lesch-Nyhan disease as a model disorder. [PDF]
Nguyen KV.
europepmc +1 more source
Exploring <i>T. cruzi</i> IMPDH as a promising target through Chagas Box screening and AVN-944 inhibition. [PDF]
Lobo-Rojas A +6 more
europepmc +1 more source
Investigation of 6-thioguanine as a strategy to overcome methotrexate resistance in a mouse model of leptomeningeal carcinomatosis. [PDF]
Nakagawa H +5 more
europepmc +1 more source
Exploring the gut microbiome and metabolomic interactions of antimetabolite drugs to optimize therapy. [PDF]
Chen J, Wang Y, Xu L, Li X, Zhao L.
europepmc +1 more source
Epidermal NAD+ deficiency induces IL-36-mediated skin inflammation and acanthosis. [PDF]
Seki T +8 more
europepmc +1 more source
Tumour Jagged1 expression as a prognostic marker of bevacizumab response and modulation of 5-fluorouracil efficacy through γ-secretase inhibition in colorectal cancer. [PDF]
García-Valdeavero OM +7 more
europepmc +1 more source

