Results 21 to 30 of about 3,080 (114)

Transcriptome Profile of Trichoderma harzianum IOC-3844 Induced by Sugarcane Bagasse [PDF]

, 2014
Profiling the transcriptome that underlies biomass degradation by the fungus Trichoderma harzianum allows the identification of gene sequences with potential application in enzymatic hydrolysis processing.
Crivelente Horta, Maria Augusta, Crucello, Aline, Cruz Pradella, Jose Geraldo da, Delabona, Priscila da Silva, Freitas, Sindelia, Kuroshu, Reginaldo Massanobu, Laborda, Prianda, Polikarpov, Igor, Souza, Anete Pereira, Vicentini, Renato   +9 more
core   +1 more source

Alkaline Phosphatase: A Reliable Endogenous Partner for Drug Delivery and Diagnostics

Advanced Therapeutics, Volume 5, Issue 2, February 2022., 2022
Alkaline phosphatase has been an endogenous partner for phosphate prodrugs for decades. More recently, it has been utilized as a reliable partner for enzyme‐responsive drug nanocarriers and diagnostic systems constructed from novel phosphate‐functionalized biomaterials.
Bao Le‐Vinh, Zeynep Burcu Akkuş‐Dağdeviren, Nguyet‐Minh Nguyen Le, Imran Nazir, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Identifcation of small molecule enzyme inhibitors as broad-spectrum anthelmintics [PDF]

, 2019
Targeting chokepoint enzymes in metabolic pathways has led to new drugs for cancers, autoimmune disorders and infectious diseases. This is also a cornerstone approach for discovery and development of anthelmintics against nematode and flatworm parasites.
Aroian, Raffi V., Brindley, Paul J., Bulman, Christina A., Elfawal, Mostafa A., Helander, Jon, Janetka, James W., Mitreva, Makedonka, Rosa, Bruce A., Sakanari, Judy, Tyagi, Rahul, Wildman, Scott A.   +10 more
core   +3 more sources

Strategies of organic phosphorus recycling by soil bacteria: acquisition, metabolism, and regulation

Environmental Microbiology Reports, Volume 14, Issue 1, Page 3-24, February 2022., 2022
Summary Critical to meeting cellular phosphorus (P) demand, soil bacteria deploy a number of strategies to overcome limitation in inorganic P (Pi) in soils. As a significant contributor to P recycling, soil bacteria secrete extracellular enzymes to degrade organic P (Po) in soils into the readily bioavailable Pi.
Yeonsoo Park, Mina Solhtalab, Wiriya Thongsomboon, Ludmilla Aristilde   +3 more
wiley   +1 more source

IL1RN and PRRX1 as a Prognostic Biomarker Correlated with Immune Infiltrates in Colorectal Cancer: Evidence from Bioinformatic Analysis

International Journal of Genomics, Volume 2022, Issue 1, 2022., 2022
The extensive morbidity of colorectal cancer (CRC) and the inferior prognosis of terminal CRC urgently call for reliable prognostic biomarkers. For this, we identified 704 differentially expressed genes (DEGs) by intersecting three datasets, GSE41328, GSE37364, and GSE15960 from Gene Expression Omnibus database, to maximize the accuracy of the results.
Qi Wang, Xufeng Huang, Shujing Zhou, Yuntao Ding, Huizhi Wang, Weiye Jiang, Min Xu, Monika Dmitrzak-Weglarz   +7 more
wiley   +1 more source

Asymmetric Addition and Cycloaddition Reactions with Ylidene‐Five‐Membered Heterocycles

Advanced Synthesis &Catalysis, Volume 363, Issue 23, Page 5196-5234, December 7, 2021., 2021
Abstract Five‐membered heterocycles bearing an exocyclic double bond have been successfully used as substrates in asymmetric addition and cycloaddition reactions. Ylidene‐heterocycles are attractive substrates due to their high functionalization and the presence of an electrophilic conjugated exocyclic double bound that can participate in nucleophilic ...
Ricardo Torán, Rubén Miguélez, Amparo Sanz‐Marco, Carlos Vila, José R. Pedro, Gonzalo Blay   +5 more
wiley   +1 more source

Complementary Sources of Protein Functional Information: The Far Side of GO. [PDF]

, 2016
The GO captures many aspects of functional annotations, but there are other alternative complementary sources of protein function information. For example, enzyme functional annotations are described in a range of resources from the Enzyme Commission (E ...
Furnham, N
core   +1 more source

Metal Fluorides as Analogs for Studies on Phosphoryl Transfer Enzymes [PDF]

, 2017
The 1994 structure of a transition state analog with AlF4- and GDP complexed to G1, a small G protein, heralded a new field of research into structure and mechanism of enzymes that manipulate transfer of the phosphoryl (PO3-) group.
Admiraal, Anderson, Antony, Batsanov, Baur, Baxter, Baxter, Baxter, Baxter, Berente, Bigay, Blackburn, Blackburn, Bock, Boone, Bowler, Bruice, Brunk, Burgos, Cavalli, Cleland, Cliff, Coleman, Du, Field, Fisher, Fovet, Frey, Geerlings, Graham, Graham, Griffin, Grigorenko, Grigorenko, Hemsworth, Henry, Higashijima, Hilbert, Himo, Hoffman, Hur, Issartel, Jackson, Jin, Jin, Jin, Kamerlin, Khrenova, Klink, Klähn, Knowles, Kowalinski, Lahiri, Lassila, Leigh, Lienhard, Liu, Lowe, Madhusudan, Maegley, Marcos, Martin, Martin, Maruta, Mesmer, Mildvan, Oldfield, Park, Pauling, Plotnikov, Praefcke, Prasad, Pylypenko, Pérez-Gallegos, Pérez-Gallegos, Ribeiro, Rittinger, Scheffzek, Schlichting, Schlichting, Senn, Sheftic, Shinoda, Shurki, Siegbahn, Smith, Sondek, Sośnicki, Sternweis, Thorsell, Topol, Toyoshima, Valiev, Wang, Warshel, Webster, Wolfenden, Zhang   +97 more
core   +5 more sources

Rates of Spontaneous Cleavage of Glucose, Fructose, Sucrose, and Trehalose in Water, and the Catalytic Proficiencies of Invertase and Trehalas [PDF]

, 2008
Most of the early experimental work on enzyme kinetics was based on the properties of yeast invertase (-fructo-furanosidase, EC 3.2.1.26), whose robust activity1 (together with the availability of a continuous polarimetric assay) enabled Michaelis and ...
Wolfenden, Richard, Yuan, Yang
core   +3 more sources

Mass Spectrometric Analyses of Organophosphate Insecticide Oxon Protein Adducts [PDF]

, 2010
OBJECTIVE: Organophosphate (OP) insecticides continue to be used to control insect pests. Acute and chronic exposures to OP insecticides have been documented-to cause adverse health effects, but few OP-adducted proteins have been correlated with these ...
Albuquerque EX, Ballantyne B, Broomfield CA, Casida JE, Charles M. Thompson, Eto M, Fest C, Huff RA, Johal MS, John M. Prins, Kathleen M. George, Katz L, Lockridge O, Richards P, Roberts WL, U.S. EPA, van den Beukel I, Wilson BW, Wilson BW, Zaim M, Zwiener RJ   +20 more
core   +3 more sources