A foszforilációs-defoszforilációs jelátviteli útvonalak kölcsönhatásai a szabad gyökök által kiváltott jelátviteli pályákkal = Cross-talk between phosphorylation-dephosphorylation and free radical-mediated signal transduction pathways [PDF]
A peroxinitrit humán keratinocita (HaCaT) sejtekben intracelluláris kalcium mobilizációt okoz. Igazoltuk a kalcium mobilizáció szerepét mind az apoptotikus, mind a nekrotikus sejthalálban.
Bai, Péter+7 more
core
Evolutionary history of Leishmania killicki (synonymous Leishmania tropica) and taxonomic implications [PDF]
Background: Leishmania (L.) killicki is responsible for the chronic cutaneous leishmaniasis. The taxonomic status of this parasite is still not well defined. It was suggested on one hand to include this taxon within L.
Babba, Hamouda+11 more
core +2 more sources
ABSTRACT Background The prognosis of biliary tract cancer (BTC) is poor, and recurrence rates remain high even after curative resection. This study aimed to compare the efficacy and safety of capecitabine and 5‐fluorouracil/leucovorin (FL) as adjuvant treatments following curative resection in patients with BTC.
Tae Seung Lee+13 more
wiley +1 more source
Purification and characterisation of phosphorylase from muscle of Tilapia (Tilapia mosambica) [PDF]
Phosphorylase from muscle of tilapia (Tilapia mosambica) was extracted by water and purified by ammonium sulphate precipitation, centrifugation and repeated recrystallisation.
Mukundan, M.K., Nair, M.R.
core
ABSTRACT The increasing frequency of concurrent heat and drought stress poses a significant challenge to agricultural productivity, particularly for cool‐season grain legumes, including broad bean (Vicia Faba L.), lupin (Lupinus spp.), lentil (Lens culinaris Medik), chickpea (Cicer arietinum L.), grasspea (Lathyrus sativus L.), pea (Pisum sativum L ...
Manu Priya+2 more
wiley +1 more source
In silico antimalarial bioprospecting of neem (Azadirachta indica) quinine-derivative alkaloids
Malaria, driven by the protozoan Plasmodium spp. and transmitted by Anopheles mosquitoes, remains a significant global health threat. With the emergence of chloroquine-resistant malaria, alternative treatments derived from natural compounds are pressing.
Alfin Hidayat+4 more
doaj +1 more source
Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human Equilibrative Nucleoside Transporter and the human Facilitative Nucleobase Transporter [PDF]
<b>Background</b>: Plasmodium parasites are unable to synthesize purines de novo and have to salvage them from the host. Due to this limitation in the parasite, purine transporters have been an area of focus in the search for anti-malarial ...
De Koning, H.P.+2 more
core +4 more sources
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong+18 more
wiley +1 more source
Biosynthesis of starch is catalyzed by a cascade of enzymes. The activity of a large number of these enzymes depends on interaction with polymeric substrates via carbohydrate binding sites, which are situated outside of the catalytic site and its ...
Casper Wilkens+2 more
doaj +1 more source
Similar Microbial Communities Found on Two Distant Seafloor Basalts. [PDF]
The oceanic crust forms two thirds of the Earth's surface and hosts a large phylogenetic and functional diversity of microorganisms. While advances have been made in the sedimentary realm, our understanding of the igneous rock portion as a microbial ...
Chong, Lauren S+3 more
core +3 more sources