Results 101 to 110 of about 38,432 (313)

Human FASTK preferentially binds single‐stranded and G‐rich RNA

The FEBS Journal, EarlyView.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak, Dawid A. Dzadz, Mikołaj I. Kuska, Madhuri Kanavalli, Maria M. Klimecka, Matthew Merski, Katarzyna J. Bandyra, Maria W. Górna   +7 more
wiley   +1 more source

Efficient Synthesis of Purine Nucleoside Analogs by a New Trimeric Purine Nucleoside Phosphorylase from Aneurinibacillus migulanus AM007

Molecules, 2019
Purine nucleoside phosphorylases (PNPs) are promising biocatalysts for the synthesis of purine nucleoside analogs. Although a number of PNPs have been reported, the development of highly efficient enzymes for industrial applications is still in high ...
Gaofei Liu, Tiantong Cheng, Jianlin Chu, Sui Li, Bingfang He   +4 more
doaj   +1 more source

Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human Equilibrative Nucleoside Transporter and the human Facilitative Nucleobase Transporter [PDF]

, 2010
<b>Background</b>: Plasmodium parasites are unable to synthesize purines de novo and have to salvage them from the host. Due to this limitation in the parasite, purine transporters have been an area of focus in the search for anti-malarial ...
De Koning, H.P., Quashie, N.B., Ranford-Cartwright, L.C.   +2 more
core   +4 more sources

Late Stage Mannan Metabolism in Cellvibrio japonicus Requires the Combined Action of a Mannosyl‐Glucose Phosphorylase and a Mannobiose Epimerase

Molecular Microbiology, EarlyView.
Model for the non‐PTS utilization of manno‐oligosaccharides by Cellvibrio japonicus. The Mgp130A and EpiA enzymes are essential for the utilization of mannose residues. ABSTRACT Manno‐oligosaccharides and their metabolism play important roles in gut health, pharmaceutical development, and renewable chemical production.
Jessica K. Novak, Jeffrey G. Gardner
wiley   +1 more source

Synthetic, enzyme kinetic, and protein crystallographic studies of C-[béta]-D-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase [PDF]

, 2016
LBK
Batta, Gyula, Bokor, Éva, Chatzileontiadou, Demetra S. M., Docsa, Tibor, Gergely, Pál, Juhász-Tóth, Éva, Kantsadi, Anastassia L., Kun, Sándor, Leonidas, Demetres D., Somsák, László, Stravodimos, George A., Szakács, Andrea   +11 more
core   +1 more source

Histochemical Demonstration of Phosphorylase a, Phosphorylase b and Phosphorylase Kinase in Normal Human Skin

The Tohoku Journal of Experimental Medicine, 1965
By the use of the theoretical control procedure, the localization of phosphorylase a, phosphorylase b and phosphorylase kinase was studied in biopsy specimens of normal human skin. In the epidermis, a weak phosphorylase a activity and moderate activities of both phosphorylase b and phosphorylase kinase were found throughout the stratum malpighii except
openaire   +3 more sources

A novel single‐cell NAD‐ME C4 subtype integrated with CAM and bicarbonate use in an aquatic plant

New Phytologist, EarlyView.
Summary Many plants maximize photosynthesis by using a CO2‐concentrating mechanism (CCM). Based on physiology, the freshwater plant Ottelia alismoides has three CCMs: C4 metabolism (NAD‐malic enzyme (NAD‐ME) subtype) and bicarbonate‐use during the day plus crassulacean acid metabolism (CAM) at night and lacks Kranz anatomy. Here, we combined a range of
Hong Sheng Jiang, Wenmin Huang, Shijuan Han, Pengpeng Li, Zuying Liao, Liyuan Wei, Lei Zhao, Shuping Gu, Jun Ding, Brigitte Gontero, Stephen C. Maberly, Wei Li   +11 more
wiley   +1 more source

Glikoenzim-inhibítorok előállítása = Synthesis of glycoenzyme inhibitors [PDF]

, 2008
A szénhidrát alapú gyógyszerek kifejlesztésének egyik iránya a glikoenzimek gátlószereinek és szerkezet?hatás összefüggéseiknek (SAR) felderítése. A kutatás során glikozidázokat, amilázokat és glikogén foszforilázokat (GP) gátló cukorszármazékokat ...
Czifrák, Katalin, Györgydeák, Zoltán, Hadady, Zsuzsa, Nagy, Veronika, Somsák, László, Vágvölgyiné dr.Tóth, Marietta   +5 more
core  

ZmMYB127 Modulates Maize Kernel Texture and Size by Integrating the Synthesis of Starch, Zein Proteins and Auxin

Plant Biotechnology Journal, EarlyView.
ABSTRACT Kernel texture is an important agronomic trait that determines the end‐uses of maize kernels and affects their integrity at harvest and susceptibility to pests and diseases. The ratio of the vitreous endosperm (RVE) is the key index for assessing kernel texture, and identifying key genes involved in its formation is crucial for maize breeding.
Tiandan Long, Yayun Wang, Zhou Liu, Yongbin Wang, Changqing Mao, Dening Wang, Aying Qin, Qiang Liao, Jin Yang, Xiujun Fan, Lei Gao, Yufeng Hu, Jing Wang, Yubi Huang, Yangping Li   +14 more
wiley   +1 more source

NTRC Plays a Crucial Role in Starch Metabolism, Redox Balance, and Tomato Fruit Growth [PDF]

, 2019
NADPH-thioredoxin reductase C (NTRC) forms a separate thiol-reduction cascade in plastids, combining both NADPHthioredoxin reductase and thioredoxin activities on a single polypeptide.
Cejudo Fernández, Francisco Javier, Ehrlich, Matthias, Fernie, Alisdair R., Geigenbergera, Peter, Hou, Liang-Yu, Krahnert, Ina, Lehmann, Martin, Obata, Toshihiro, Thormählen, Ina   +8 more
core   +1 more source