Results 21 to 30 of about 3,382 (177)

Discovery of a Kojibiose Hydrolase by Analysis of Specificity-Determining Correlated Positions in Glycoside Hydrolase Family 65

Molecules, 2021
The Glycoside Hydrolase Family 65 (GH65) is an enzyme family of inverting α-glucoside phosphorylases and hydrolases that currently contains 10 characterized enzyme specificities. However, its sequence diversity has never been studied in detail.
Emma De Beul, Alana Jongbloet, Jorick Franceus, Tom Desmet   +3 more
doaj   +1 more source

Evolution of phosphorylases from N-acetylglucosaminide hydrolases in family GH3

, 2021
Glycoside phosphorylases hold great potential as catalysts for the synthesis of valuable sugars, glycosides, and glycans or for the development of energy-efficient microbial cell factories.
Cools, Lore, Lormans, Jolien, Franceus, Jorick, D'hooghe, Matthias, Desmet, Tom   +4 more
core   +1 more source

Nucleoside Phosphorylases [PDF]

, 2006
Nucleoside phosphorylases (NPs) are transferases that catalyse the reversible cleavage of the glycosidic bond of ribo- or deoxyribo nucleosides, in the presence of inorganic phosphate, to generate the base and ribose- or deoxyribose- 1-phosphate.
Iribarren, Adolfo Marcelo, Lewkowicz, Elizabeth Sandra   +1 more
core   +1 more source

Hemodialysis in MNGIE transiently reduces serum and urine levels of thymidine and deoxyuridine, but not CSF levels and neurological function

Orphanet Journal of Rare Diseases, 2017
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare, autosomal-recessive mitochondrial disorder caused by TYMP mutations presenting with a multisystemic, often lethal syndrome of progressive leukoencephalopathy, ophthalmoparesis ...
Benjamin Röeben, Justus Marquetand, Benjamin Bender, Heiko Billing, Tobias B. Haack, Iciar Sanchez-Albisua, Ludger Schöls, Henk J. Blom, Matthis Synofzik   +8 more
doaj   +1 more source

Two new gene clusters involved in the degradation of plant cell wall from the fecal microbiota of Tunisian dromedary. [PDF]

PLoS ONE, 2018
Dromedaries are capable of digesting plant cell wall with high content of lignocellulose of poor digestibility. Consequently, their intestinal microbiota can be a source of novel carbohydrate-active enzymes (CAZymes).
Rihab Ameri, Elisabeth Laville, Gabrielle Potocki-Véronèse, Sahar Trabelsi, Monia Mezghani, Fatma Elgharbi, Samir Bejar   +6 more
doaj   +1 more source

RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities

Nature Communications, 2017
The yeast and human RNA exosome is structurally related to prokaryotic phosphorylases but degrades RNA only via associated hydrolytic activities. Here the authors show that the RNA exosome of plants, and likely those of a few basal eukaryotes, combines ...
Natalia Sikorska, Hélène Zuber, Anthony Gobert, Heike Lange, Dominique Gagliardi   +4 more
doaj   +1 more source

HvPHO1 Controls a Glucose 1-Phosphate-SnRK1 Signalling Module That Coordinates Starch Accumulation in Barley Endosperm. [PDF]

Plant Biotechnol J
ABSTRACT Developing barley grains must balance the use of imported sucrose between soluble sugars and storage starch, but how this balance is controlled remains unclear. Here we show that loss of the plastidial α‐glucan phosphorylase HvPHO1 causes starch and soluble sugars to accumulate concurrently in barley grains.
Li Y, Chen Y, Liu J, Yang P, Gao G, Guzmán C, Xu Q, Zhang Y, Liu Y, Qi P, Deng M, Dai S, Ma J, Chen G, Wang J, Zheng Y, Wei Y, Jiang Q.   +17 more
europepmc   +2 more sources

Three novel oligosaccharides synthesized using Thermoanaerobacter brockii kojibiose phosphorylase

Chemistry Central Journal, 2007
Background Recently synthesized novel oligosaccharides have been produced primarily by hydrolases and glycosyltransferases, while phosphorylases have also been subject of few studies.
Nishimoto Tomoyuki, Benkeblia Noureddine, Onodera Shuichi, Fukushi Eri, Takahashi Natsuko, Kawabata Jun, Shiomi Norio   +6 more
doaj   +1 more source

Enzymatic synthesis and phosphorolysis of 4(2)-thioxo- and 6(5)-azapyrimidine nucleosides by E. coli nucleoside phosphorylases

Beilstein Journal of Organic Chemistry, 2016
The trans-2-deoxyribosylation of 4-thiouracil (4SUra) and 2-thiouracil (2SUra), as well as 6-azauracil, 6-azathymine and 6-aza-2-thiothymine was studied using dG and E.
Vladimir A. Stepchenko, Anatoly I. Miroshnikov, Frank Seela, Igor A. Mikhailopulo   +3 more
doaj   +1 more source

Discovery of solabiose phosphorylase and its application for enzymatic synthesis of solabiose from sucrose and lactose

Scientific Reports, 2022
Glycoside phosphorylases (GPs), which catalyze the reversible phosphorolysis of glycosides, are promising enzymes for the efficient production of glycosides.
Wataru Saburi, Takanori Nihira, Hiroyuki Nakai, Motomitsu Kitaoka, Haruhide Mori   +4 more
doaj   +1 more source