Results 241 to 250 of about 1,554,099 (296)

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Phosphorylation shapes antigen presentation and immune recognition: mechanistic insights and translational perspectives. [PDF]

Front Immunol
Rijal R, Marques AF.
europepmc   +1 more source

The Edwardsiella T3SS effector EseJ enhances NF-κB signaling by stabilizing p65 and promoting TAK1 phosphorylation. [PDF]

PLoS Pathog
He TT, Tang PY, Zhao QR, Zhang J, Nie P, Yu HB, Xie HX.   +6 more
europepmc   +1 more source

Tau abnormalities and microglial remodeling in glaucoma: potential links to phagocytosis-related injury. [PDF]

Front Neurol
Li C, Song R, Yu L.
europepmc   +1 more source

Curcumin Pretreatment Alleviates Early Mannheimia Haemolytica-Induced Pulmonary Injury in Mice and Is Associated with Changes in Gut Microbial Composition. [PDF]

Microorganisms
Zhao F, Huang Y, Wu S, Fu Y, Zhang X, Li Z, An X, Zhang K, Shen L, Cao S, Zhang H, Shen X, Yu S.   +12 more
europepmc   +1 more source