Results 181 to 190 of about 2,046,842 (395)

Cardiac Myosin-Binding Protein-C Phosphorylation and Cardiac Function

, 2005
Sakthivel Sadayappan, James Gulick, Hanna Osińska, Lisa Martin, Harvey S. Hahn, Gerald W. Dorn, Raisa Klevitsky, Christine E. Seidman, Jonathan G. Seidman, Jeffrey Robbins   +9 more
openalex   +1 more source

RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases [PDF]

, 2017
Geng‐Xian Shi, Won Seok Yang, Ling Jin, Michelle L. Matter, Joe W. Ramos   +4 more
openalex   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Design and Synthesis of Novel Candidate CK1δ Proteolysis Targeting Chimeras (PROTACs)

Molecules
The dysregulation of CK1 isoforms is linked to various types of diseases, including neurodegeneration and different types of neoplasia such as colon, pancreatic, breast, and ovarian cancer.
Malte Arnold, Temi Thompson, Lorraine Glennie, Mattes Hollnagel, Gopal Sapkota, Christian Peifer   +5 more
doaj   +1 more source

Tyrosine phosphorylation of LRP 6 by Src and Fer inhibits Wnt/β‐catenin signalling [PDF]

, 2014
Qing Chen, Yi Su, Janine Wesslowski, Anja I.H. Hagemann, Mirana Ramialison, Joachim Wittbrodt, Steffen Scholpp, Gary Davidson   +7 more
openalex   +1 more source

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Cell, 1997
S. R. Datta, H. Dudek, Xu Tao, S. Masters, H. Fu, Y. Gotoh, M. Greenberg   +6 more
semanticscholar   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Enhanced Salt Tolerance of Rhizobia-inoculated Soybean Correlates with Decreased Phosphorylation of the Transcription Factor GmMYB183 and Altered Flavonoid Biosynthesis [PDF]

, 2019
Erxu Pi, Jia Xu, Huihui Li, Wei Fan, Chengmin Zhu, Tongyao Zhang, Jiachen Jiang, Litao He, Hongfei Lu, Huizhong Wang, B. W. Poovaiah, Liqun Du   +11 more
openalex   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Binding of DC-HIL to Dermatophytic Fungi Induces Tyrosine Phosphorylation and Potentiates Antigen Presenting Cell Function [PDF]

, 2009
Jin-Sung Chung, Tatsuo Yudate, Mizuki Tomihari, Hideo Akiyoshi, Ponciano D. Cruz, Kiyoshi Ariizumi   +5 more
openalex   +1 more source