Results 181 to 190 of about 1,001,349 (289)

Studies of Foxo1 over the Past 25 Years: Mechanisms of Insulin Resistance and Glucose Dysregulation. [PDF]

Cells
Yang W, Guo J, Song J, Guo S.
europepmc   +1 more source

e0016 Tongxinluo reduces myocardial ischaemia-reperfusion injury and no-reflow by stimulating the expression and phosphorylation of eNOS via PKA pathway [PDF]

, 2010
Xue Li, Yue Yang, Yong‐Jian Geng, Chunhua Jin, F.-H. Hu, Jinbo Zhao, H.-T. Zhang, Yang Cheng, Heying Qian, L.-L. Wang, Boli Zhang, Yechen Wu   +11 more
openalex   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Study on the phosphorylation of NAD⁺-specific isocitrate dehydrogenase in the pathogenic bacteria <i>Stenotrophomonas maltophilia</i> and <i>Xanthomonas sacchari</i>. [PDF]

J Enzyme Inhib Med Chem
Tian Q, Zhang Y, Pan C, Wang L, Qin N, Jiang Z, Li C, Cao Z, Zhu G, Wang P.   +9 more
europepmc   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

PP2A activation targets MYCN in neuroblastoma. [PDF]

Cell Death Dis
Nazam N, Manzoor S, Shaikh M, Brown ML, Julson JR, Quinn CH, Butey S, Shirley SN, Aye JM, Yoon K, Leavenworth JW, Ohlmeyer M, Beierle EA.   +12 more
europepmc   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Ser500 phosphorylation acts as a conformational switch to prime eEF-2K for activation. [PDF]

J Biol Chem
Bohanon AL, Browning LS, Piserchio A, Long KJ, Jacob S, Sammons RM, Tavares CDJ, Cho EJ, Ghose R, Dalby KN.   +9 more
europepmc   +1 more source

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Calcium signaling-mediated phosphorylation controls zinc allocation in Arabidopsis. [PDF]

Stress Biol
Fang Y, Liu F, Yang C, Ma X, Wang C, Zhang Z, Ju C.   +6 more
europepmc   +1 more source