Results 171 to 180 of about 1,166,192 (319)

Platelet Drp1 phosphorylation provides a platform for immune-based platelet function testing. [PDF]

Blood
Barrios DA, Guo S, Powers M, Koseoglu S, Zerbey S, Lu R, Cermak A, Vayne C, Khan S, Aisiku O, Urman A, Thomas J, Patell R, Zwicker JI, Flaumenhaft R.   +14 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

2-Hydroxyisobutyrylation and Phosphorylation Crosstalk Guides Metastasis Prediction and Immunotherapy in Esophageal Squamous Cell Carcinoma. [PDF]

MedComm (2020)
Li J, Li S, Yu X, Mu Q, Luo M, Wang Y, Liu Z, Gu C, Chen J, He W, Yang T, He Y, Pei X, Lin M, Li Z, Liu J, Zhao B, Zhang F, Liu J, Li B, Xu W.   +20 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Deciphering O‑GlcNAc-Dependent Signaling Via Integrated Proteomics and Phosphoproteomics. [PDF]

ACS Omega
Wu C, Hou C, Wang X, Peng Y, Lin Y, Byers SW, Pei H, Ma J.   +7 more
europepmc   +1 more source

Oxidative Phosphorylation [PDF]

Journal of Pharmacy and Pharmacology, 1959
openaire   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Phosphoproteomics in Vascular Biology and Disease: Illuminating Signaling in the Vessel. [PDF]

Arterioscler Thromb Vasc Biol
Voos K, He M, Many GM, Chen Y, Qian WJ.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Phosphoproteomics Preliminarily Revealed the Differential Phosphorylation Sites and Their Functional Significance in the Longissimus Dorsi Muscle of Kazakh and Xinjiang Brown Cattle. [PDF]

Food Sci Nutr
Wumaier A, Ma Z, Chen W, Liu M, Chen S, Wang S, Wang W, Wang X, Yan X, Chen L.   +9 more
europepmc   +1 more source