Results 191 to 200 of about 1,642,696 (345)

On the Mode of Action of 2,4-Dinitrophenol in Uncoupling Oxidative Phosphorylation

, 1958
George R. Drysdale, Mildred Cohn
openalex   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

THE EFFICIENCY OF OXIDATIVE PHOSPHORYLATION IN MITOCHONDRIA FROM DIABETIC RATS

, 1955
Robert E. Parks, Julius Adler, John H. Copenhaver   +2 more
openalex   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Oxidative Phosphorylation by Mitochondrial Suspensions after Freezing and Storage at Low Temperatures

, 1958
C.A. Privitera, Donald Greiff, D.R. Strength, M. Anglin, Henry Pinkerton   +4 more
openalex   +1 more source

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

FEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki, Hiroki Okanishi, Yoshikatsu Kanai, Ryoji Masui   +3 more
wiley   +1 more source

Global comparative structural analysis of responses to protein phosphorylation. [PDF]

Nat Commun
Correa Marrero M, Mello VH, Sartori P, Beltrao P.   +3 more
europepmc   +1 more source

ENZYMATIC OXIDATION OF α-KETOGLUTARATE AND COUPLED PHOSPHORYLATION

, 1953
Seymour Kaufman, Charles Gilvarg, Osvaldo Cori, Severo Ochoa   +3 more
openalex   +1 more source

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

FEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco, Roxana Olguín‐Alor, Lizbeth Bolaños‐Castro, Alexandra Morales‐Cruz, Marisol De La Fuente‐Granada, Gloria Soldevila   +5 more
wiley   +1 more source

Comprehensive phosphoproteomic profiling reveals sex-specific regulatory mechanisms in HrasG12V-driven hepatocarcinogenesis. [PDF]

Cancer Cell Int
Yang C, Hu J, Yao L, Yu Y, Dong X, Chen J, Wang A, Li H.   +7 more
europepmc   +1 more source