Results 11 to 20 of about 22,858 (260)

Differential contributions of choline phosphotransferases CPT1 and CEPT1 to the biosynthesis of choline phospholipids

open access: yesJournal of Lipid Research, 2021
Choline phospholipids (PLs) such as phosphatidylcholine (PC) and 1-alkyl-2-acyl-sn-glycerophosphocholine are important components for cell membranes and also serve as a source of several lipid mediators.
Yasuhiro Horibata, Hiroyuki Sugimoto
doaj   +2 more sources

Aminoglycoside phosphotransferases proteins structure and mechanism [PDF]

open access: yesFrontiers in Bioscience, 1999
Aminoglycoside antibiotics constitute an important class of clinically useful drugs which are imperiled by the emergence of resistant organisms. Aminoglycoside resistance in the clinics is primarily due to the presence of modifying enzymes which N-acetylate, O-adenylate or O-phosphorylate the antibiotics.
Wright, G. D., Thompson, Paul R
openaire   +5 more sources

Locations and contributions of the phosphotransferases EPT1 and CEPT1 to the biosynthesis of ethanolamine phospholipids[S]

open access: yesJournal of Lipid Research, 2020
The final step of the CDP-ethanolamine pathway is catalyzed by ethanolamine phosphotransferase 1 (EPT1) and choline/EPT1 (CEPT1). These enzymes are likely involved in the transfer of ethanolamine phosphate from CDP-ethanolamine to lipid acceptors such as
Yasuhiro Horibata   +2 more
doaj   +2 more sources

Effects of precursors on kitasamycin production in Streptomyces kitasatoensis

open access: yesBioscience Journal, 2019
To improve kitasamycin biosynthesis by Streptomyces kitasatoensis Z-7, the addition of two precursors, sodium acetate and ethyl acetate, to the fermentation medium was evaluated.
Xiong Zheng   +4 more
doaj   +3 more sources

Identification of a protein kinase activity that phosphorylates connexin43 in a pH-dependent manner

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The carboxyl-terminal (CT) domain of connexin43 (Cx43) has been implicated in both hormonal and pH-dependent gating of the gap junction channel. An in vitro assay was utilized to determine whether the acidification of cell extracts results in the ...
P. Yahuaca   +4 more
doaj   +1 more source

The unphosphorylated EIIA(Ntr) protein represses the synthesis of alkylresorcinols in Azotobacter vinelandii. [PDF]

open access: yesPLoS ONE, 2015
Upon encystment induction, Azotobacter vinelandii produces the phenolic lipids alkylresorcinols (ARs) that are structural components of the cysts. The enzymes responsible for the ARs synthesis are encoded in the arsABCD operon, whose expression is ...
Luis Felipe Muriel-Millán   +6 more
doaj   +1 more source

Protein Model and Function Analysis in Quorum-Sensing Pathway of Vibrio qinghaiensis sp.-Q67

open access: yesBiology, 2021
Bioluminescent bacteria are mainly found in marine habitats. Vibrio qinghaiensis sp.-Q67 (Q67), a nonpathogenic freshwater bacterium, has been a focus due to its wide use in the monitoring of environmental pollution and the assessment of toxicity ...
Ze-Jun Wang   +4 more
doaj   +1 more source

Aminoglycoside 3'-phosphotransferase III, a new phosphotransferase. Resistance mechanism.

open access: yesThe Journal of Antibiotics, 1975
The aminoglycoside phosphotransferase of Pseudomonas aeruginosa 21-75 was purified by affinity chromatography using dibekacin-Sephadex 4B or lividomycin A-Sepharose 4B followed by DEAE Sephadex A-50 chromatography. It had activities of both the known aminoglycoside 3'-phosphotransferases I and II, and transferred phosphate from ATP to the 3'-hydroxyl ...
Tsutomu Sawa   +6 more
openaire   +4 more sources

Structural basis for the diversity of the mechanism of nucleotide hydrolysis by the aminoglycoside-2''-phosphotransferases.

open access: yesActa Crystallographica Section D: Structural Biology, 2019
Aminoglycoside phosphotransferases (APHs) are one of three families of aminoglycoside-modifying enzymes that confer high-level resistance to the aminoglycoside antibiotics via enzymatic modification.
Clyde A. Smith   +4 more
semanticscholar   +1 more source

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