Results 31 to 40 of about 11,871 (215)

An Adaptation To Life In Acid Through A Novel Mevalonate Pathway. [PDF]

, 2016
Extreme acidophiles are capable of growth at pH values near zero. Sustaining life in acidic environments requires extensive adaptations of membranes, proton pumps, and DNA repair mechanisms.
Bowie, James U, Cummins, Matthew C, Korman, Tyler P, Vinokur, Jeffrey M   +3 more
core   +1 more source

Late G1 Cell Cycle Molecular Pathways

MedEdPORTAL, 2008
The most critical stage of the cell cycle is the transition point in late G1 where the cell commits to initiating DNA synthesis. Multiple pathways of stimulation and inhibition converge, and it can be difficult for students to comprehend how all these ...
Dan Cushman, Robert Warren
doaj   +1 more source

Comparative Phylogenomics of Pathogenic and Nonpathogenic Species. [PDF]

, 2015
The Ascomycete Onygenales order embraces a diverse group of mammalian pathogens, including the yeast-forming dimorphic fungal pathogens Histoplasma capsulatum, Paracoccidioides spp. and Blastomyces dermatitidis, the dermatophytes Microsporum spp.
Taylor, John W, Whiston, Emily
core   +3 more sources

Look and Outlook on Enzyme-Mediated Macrolide Resistance

Frontiers in Microbiology, 2018
Since their discovery in the early 1950s, macrolide antibiotics have been used in both agriculture and medicine. Specifically, macrolides such as erythromycin and azithromycin have found use as substitutes for β-lactam antibiotics in patients with ...
Tolou Golkar, Michał Zieliński, Albert M. Berghuis, Albert M. Berghuis   +3 more
doaj   +1 more source

AglH, a thermophilic UDP‑N‑acetylglucosamine‑1‑phosphate:dolichyl phosphate GlcNAc‑1‑phosphotransferase initiating protein N‑glycosylation pathway in Sulfolobus acidocaldarius, is capable of complementing the eukaryal Alg7 [PDF]

, 2016
AglH, a predicted UDP-GlcNAc-1-phosphate:dolichyl phosphate GlcNAc-1-phosphotransferase, is initiating the protein N-glycosylation pathway in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius. AglH successfully replaced the endogenous GlcNAc-1-
A Bouhss, A Larkin, A Larkin, A Spang, A Typas, AJ Lloyd, AO Amer, AO Amer, AR Nogare Dal, B Chaban, B Chaban, Benjamin H. Meyer, BH Meyer, BH Meyer, BH Meyer, C Ginsberg, C Whitfield, C Yanisch-Perron, D Calo, D Calo, D Mumberg, DC Alexander, DJ Mancuso, DW Grogan, E Hartmann, FA Troy, G Paul, G Samuel, G Schmidt, H Shams-Eldin, Hosam Shams-Eldin, J Jaeken, J Lehrer, J Lu, JD Esko, JM Archibald, K Hjort, KF Jarrell, KJ Glover, KJ Stone, KR Mclachlan, L Guy, L Kaminski, L Masson, L Xu, M Wagner, M Wagner, MA Lehrman, MG Elferink, MM Chang, MS Anderson, N Kurosawa, O Wurtzel, P Burda, PA Amor, R Mazhari-Tabrizi, RS Sikorski, S Brown, S Ohnuma, S Ohnuma, S Yamashita, S Yurist-Doutsch, Sonja-Verena Albers, TD Brock, TD Bugg, U Meier-Dieter, U Zahringer, V Eckert, W Meyer, Y Boucher, Y Taguchi, Z Guan, Z Guan, ZQ Guan   +73 more
core   +2 more sources

Bacterial resistance to antimicrobial agents and its impact on veterinary and human medicine [PDF]

, 2016
Background Antimicrobial resistance has become a major challenge in veterinary medicine, particularly in the context of bacterial pathogens that play a role in both humans and animals.
Aarestrup, Abedon, Arais, Becker, Bikard, Blondeau, Brackman, Bradford, Brandenburg, Brogden, Burrus, Bush, Bush, Bywater, Chopra, Clinical and Laboratory Standards Institute, Clinical and Laboratory Standards Institute, Clinical and Laboratory Standards Institute, Connell, Couto, Cuny, D'Costa, Damborg, Duijkeren, Ewers, Ewers, Falgenhauer, Feßler, Fischetti, Fuente-Núñez, Giessen, Goh, Grobbel, Grobbel, Groves, Guardabassi, Hall, Harada, Harrison, Hill, Hillier, International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements (IWG-SCC), Kadlec, Kadlec, Kadlec, Kadlec, Kehrenberg, Köck, Laube, Lefebvre, Lindsay, Lloyd, Long, Lyon, Lüthje, Maaland, Maddox, Magiorakos, Mascaretti, McCarthy, McCarthy, McNulty, Michael, Michael, Michael, Moodley, Mueller, Nienhoff, Nobrega, O'Neill, Paterson, Perreten, Poole, Putman, Ramirez, Redgrave, Richter, Riesenberg, Roberts, Roberts, Roberts, Ruiz, Rule, Schaufler, Schmiedel, Schneider, Schuch, Schultz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Scott, Shen, Sing, Soares, Sobral, Thandar, Thomas, Tsonos, van, von, Walther, Wang, Weiß, Wendlandt, Wendlandt, Wendlandt, Wendlandt, Wendlandt, Werckenthin, Westgarth, Westgarth, White, Wu, Zervos, Zhao, Zurek   +123 more
core   +3 more sources

Multivalent Glycopolymer Design Unlocks Antimicrobial Activity of 2‐Deoxyglucose

Angewandte Chemie, EarlyView.
New approaches to combat antimicrobial‐resistant pathogens are needed. Here, scaffolding a nonmetabolizable sugar (2DG) on a polymer backbone is shown to significantly improve its antimicrobial activity. ABSTRACT With the increasing prevalence of multidrug‐resistant (MDR) pathogens, last‐line therapeutics such as cyclic peptides are insufficient ...
Sungjin Jeon, Xianjin Qin, Marjon Zamani, Ariel L. Furst, Cassandra E. Callmann   +4 more
wiley   +2 more sources

Genome-wide (ChIP-seq) identification of target genes regulated by BdbZIP10 during paraquat-induced oxidative stress

BMC Plant Biology, 2018
Background bZIP transcription factors play a significant role in many aspects of plant growth and development and also play critical regulatory roles during plant responses to various stresses.
Ruth C. Martin, Kelly Vining, James E. Dombrowski   +2 more
doaj   +1 more source

Study of the Aminoglycoside Subsistence Phenotype of Bacteria Residing in the Gut of Humans and Zoo Animals [PDF]

, 2016
Recent studies indicate that next to antibiotic resistance, bacteria are able to subsist on antibiotics as a carbon source. Here we evaluated the potential of gut bacteria from healthy human volunteers and zoo animals to subsist on antibiotics.
Gerrit eBor, Hauke eSmidt, Mark W.J. evan Passel, Mark W.J. evan Passel, Teresita De Jesus eBello Gonzalez, Tina eZuidema   +5 more
core   +3 more sources

Characterization of β-Lactamases and Multidrug Resistance Mechanisms in Enterobacterales from Hospital Effluents and Wastewater Treatment Plant

Antibiotics, 2022
Antimicrobials in wastewater promote the emergence of antibiotic resistance, facilitated by selective pressure and transfer of resistant genes. Enteric bacteria belonging to Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter ...
Christopher Mutuku, Szilvia Melegh, Krisztina Kovacs, Peter Urban, Eszter Virág, Reka Heninger, Robert Herczeg, Ágnes Sonnevend, Attila Gyenesei, Csaba Fekete, Zoltan Gazdag   +10 more
doaj   +1 more source