Results 61 to 70 of about 11,871 (215)

Ultrasensitivity of the Bacillus subtilis sporulation decision [PDF]

, 2012
Starving Bacillus subtilis cells execute a gene expression program resulting in the formation of stress-resistant spores. Sporulation master regulator, Spo0A, is activated by a phosphorelay and controls the expression of a multitude of genes, including ...
Balazsi, Bashor, Ben-Jacob, Ben-Yehuda, Burbulys, Clarkson, Doncic, Dubnau, Dworkin, Eichenberger, Eichenberger, Eldar, Errington, Errington, Errington, Fujita, Fujita, Fujita, Fujita, Fujita, Hilbert, Hoch, Hoch, Hofmeister, Iber, Igoshin, J. Narula, Kuchina, Levin, Levine, Lewis, M. Fujita, Malleshaiah, Melen, Molle, Nachman, Narula, Nicholson, O. A. Igoshin, Piggot, Quon, S. N. Devi, Schmidt, Sciammas, Smits, Sterlini, Tiwari, Tiwari, van Sinderen, Veening, Veening, Wang   +51 more
core   +1 more source

Genetically Programmed Control of Overflow Metabolism

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Overflow metabolism is a highly undesirable phenomenon that occurs in virtually all cell factories. Although several schemes have been applied to avoid overflow metabolism, this problem remains far from being solved. In this study, a genetic sensor for detecting overflow metabolism was designed, and its substrate specificity and reversibility ...
Lærke M. Jensen, Andriy Glushchuk, Thilde P. Hjorth, Alvaro R. Lara   +3 more
wiley   +1 more source

Amikacin: Uses, Resistance, and Prospects for Inhibition

Molecules, 2017
Aminoglycosides are a group of antibiotics used since the 1940s to primarily treat a broad spectrum of bacterial infections. The primary resistance mechanism against these antibiotics is enzymatic modification by aminoglycoside-modifying enzymes that are
Maria S. Ramirez, Marcelo E. Tolmasky
doaj   +1 more source

Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress. [PDF]

, 2015
Adenylate kinases (AKs) are phosphotransferases that regulate the cellular adenine nucleotide composition and play a critical role in the energy homeostasis of all tissues.
Al-Zahrani, Alberto Rissone, Alex DeVine, Aloj, Antoine, Argenton, Axel Schambach, Bandlow, Bertrand, Bertrand, Bujan, Burkart, Castaigne, Chen, Choi, Craven, Daily, De Vaal, Dzeja, Dzeja, Dzeja, Elisa Giocaliere, Fabio Candotti, Finckbeiner, Fischer, Flicek, Fujisawa, Giancarlo la Marca, Goujon, Hatefi, Henderson, Jang, Janssen, Jayashree Jagadeesh, Karen Lyn Simon, Katja Gabriele Weinacht, Kerry Dobbs, Kerstin Felgentreff, Kevin Bishop, Kimmel, Kissa, Köhler, Lagresle-Peyrou, Lagresle-Peyrou, Lawson, Le Guyader, Lee, Lee, Liesa, Lin, Liu, Luigi D. Notarangelo, Martha Kirby, Marypat Jones, Mugoni, Pannicke, Park, Park, Poliani, Pucar, Pucar, Raman Sood, Renaud, Rissone, Ryter, Sauer, Settara Chandrasekharappa, Shapiro, Sheehan, Single, Sood, Sood, Stephen Wincovitch, Takubo, Thisse, Thorsten Schlaeger, Traver, Waleed Al-Herz, Warlich, Westerfield, Whitford, Yuval Itan   +81 more
core   +4 more sources

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

Food Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei, Mengqi Qu, Ziru Yang, Xuebin Xu, Yanan Wang   +4 more
wiley   +1 more source

Chromogenic Detection of Aminoglycoside Phosphotransferases [PDF]

Antimicrobial Agents and Chemotherapy, 1998
ABSTRACT A coupled chromogenic reaction (based on an agar overlay combining NADH, pyruvate kinase, lactate dehydrogenase, phosphoenolpyruvate, ATP, and kanamycin sulfate with thiazolyl blue-phenazine methosulfate for detection of NADH consumption) was optimized for the detection of aminoglycoside phosphotransferases (APHs).
Amoroso, Ana Maria, Gutkind, G. O.
openaire   +4 more sources

Decavanadate effects in biological systems [PDF]

, 2005
Vanadium biological studies often disregarded the formation of decameric vanadate species known to interact, in vitro, with high-affinity with many proteins such as myosin and sarcoplasmic reticulum calcium pump and also to inhibit these biochemical ...
Amado, Aureliano, Aureliano, Aureliano, Aureliano, Aureliano, Aureliano, Baran, Beaugé, Beg, Borges, Byczkowski, Cantley, Capella, Chasteen, Coan, Colin, Correia, Crans, Csermely, Csermely, Davies, DeMaster, Desoize, Domingo, Dux, D’Cruz, Edel, Ferrer, Garner, Goodno, Grahame, Harland, Hasspieler, Heinemann, Hua, Josephson, Kanna, Lymn, Maurer, Medda, Messmore, Molinuevo, Molnar, Nechay, Nilius, Nriagu, Pedersen, Pezza, Rao, Rehder, Sakurai, Shechter, Soares, Stankiewicz, Stohs, Tiago, Tiago, Tiago, Tiago, Varga, Vegh, Venkataraman, Yang, Yang, Zaporowska, Zhang, Zychlinski   +67 more
core   +1 more source

Phytochemical content, antioxidant and antibacterial properties of Typhonium flagelliforme cultivated via soil and hydroponic methods

JSFA reports, EarlyView.
Abstract Background Typhonium flagelliforme is a medicinal herb in the Araceae family, widely distributed in Southeast Asia. This study aimed to evaluate the effects of hydroponic and soil‐based cultivation systems on the phytochemical content and bioactivity of T. flagelliforme. Results Using liquid chromatography‐mass spectrometry (LC‐MS) analysis, 9
Yen Ning Lee, Norsharina Md Saad, Siti Rokhiyah Ahmad Usuldin, Seetha Jaganathan King, Wee Sim Choo   +4 more
wiley   +1 more source

Enzymic synthesis of ether types of choline and ethanolamine phosphoglycerides by microsomal fractions from rat brain and liver

Journal of Lipid Research, 1977
The formation of product by ethanolamine phosphotransferases (EC 2.7.8.1) and cholinephosphotransferases (EC 2.7.8.2) in microsomal fractions from brains and livers of mature rats is increased several fold by 1,2-diacyl-sn-glycerols. With the addition of
A Radominska-Pyrek, J Strosznajder, Z Dabrowiecki, G Goracci, T Chojnacki, L A Horrocks   +5 more
doaj   +1 more source

Results of A Local Combination Therapy Antibiogram For \u3cem\u3ePseudomonas Aeruginosa\u3c/em\u3e Isolates: Is Double Worth The Trouble? [PDF]

, 2017
Purpose: To determine the frequency at which fluoroquinolones and aminoglycosides demonstrate in vitro activity against non-urinary, non-skin/skin structure Pseudomonas aeruginosa isolates exhibiting decreased susceptibilities to one or more β-lactam ...
Davis, Jim, Dilworth, Thomas J., Elshaboury, Ramy, Munson, Erik, Song, Matthew   +4 more
core   +1 more source