Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica Implications for the Evolution of the Ribokinase Superfamily [PDF]
The crystal structures of a Salmonella enterica aminoimidazole riboside (AIRs) kinase, its complex with the substrate AIRs, and its complex with AIRs and an ATP analog were determined at 2.6 Å, 2.9 Å, and 2.7 Å, respectively.
Dougherty, Michael+3 more
core +1 more source
Molecular mechanism of dietary phospholipid requirement of Atlantic salmon, Salmo salar, fry [PDF]
The phospholipid (PL) requirement in fish is revealed by enhanced performance when larvae are provided PL-enriched diets. To elucidate the molecular mechanism underlying PL requirement in Atlantic salmon, Salmo salar, were fed a minimal PL diet and ...
Carmona-Antoñanzas, Greta+3 more
core +1 more source
A structure-based proposal for the catalytic mechanism of the bacterial acid phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases [PDF]
The Escherichia coli gene aphA codes for a periplasmic acid phosphatase called AphA, belonging to class B bacterial phosphatases, which is part of the DDDD superfamily of phosphohydrolases.
Benvenuti, M+5 more
core +1 more source
Biochemical characterization of the maltokinase from Mycobacterium bovis BCG [PDF]
Background Maltose-1-phosphate was detected in Mycobacterium bovis BCG extracts in the 1960's but a maltose-1-phosphate synthetase (maltokinase, Mak) was only much later purified from Actinoplanes missouriensis, allowing the identification of the mak ...
da Costa, Milton S+4 more
core +3 more sources
Self-Resistance During Muraymycin Biosynthesis: A Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order [PDF]
Muraymycins are antibacterial natural products from Streptomyces spp. that inhibit translocase I (MraY), which is involved in cell wall biosynthesis. Structurally, muraymycins consist of a 5′-C-glycyluridine (GlyU) appended to a 5″-amino-5″-deoxyribose ...
Cui, Zheng+8 more
core +2 more sources
Decavanadate effects in biological systems [PDF]
Vanadium biological studies often disregarded the formation of decameric vanadate species known to interact, in vitro, with high-affinity with many proteins such as myosin and sarcoplasmic reticulum calcium pump and also to inhibit these biochemical ...
Amado+67 more
core +1 more source
Structural and functional insights into Mimivirus ORFans [PDF]
Background Mimivirus isolated from A. polyphaga is the largest virus discovered so far. It is unique among all the viruses in having genes related to translation, DNA repair and replication which bear close homology to eukaryotic genes.
Fischer, Daniel, Saini, Harpreet Kaur
core +3 more sources
Beyond protein modification: the rise of non-canonical ADP-ribosylation [PDF]
ADP-ribosylation has primarily been known as post-translational modification of proteins. As signalling strategy conserved in all domains of life, it modulates substrate activity, localisation, stability or interactions, thereby regulating a variety of ...
Ahel, Ivan, Schuller, Marion
core +2 more sources
The structure and function of human brain hexokinase [PDF]
An ATP binding site model for human brain hexokinase was established based on the similarity of the ATP-binding domains among actin, heat shock protein, glycerol kinase and brain hexokinase.
Zeng, Chenbo
core +2 more sources
Structure and function of enzymes involved in the anaerobic degradation of L-threonine to propionate [PDF]
In Escherichia coli and Salmonella typhimurium, L-threonine is cleaved non-oxidatively to propionate via 2-ketobutyrate by biodegradative threonine deaminase, 2-ketobutyrate formate-lyase (or pyruvate formate-lyase), phosphotransacetylase and propionate ...
Chittori, Sagar+3 more
core +1 more source