Results 21 to 30 of about 4,150 (110)

Theoretical Studies on Mechanism of Inactivation of Kanamycin A by 4′-O-Nucleotidyltransferase [PDF]

, 2019
This work is focused on mechanistic studies of the transfer of an adenylyl group (Adenoside-5′-monophosfate) from adenosine 5′-triphosphate (ATP) to a OH-4′ hydroxyl group of an antibiotic.
Agatha Bastida, Katarzyna Świderek, Sergio Martí   +2 more
core   +2 more sources

Mechanisms governing bacterial capsular polysaccharide attachment and chain length

Annals of the New York Academy of Sciences, EarlyView.
Abstract Capsular polysaccharides (CPSs) are high‐molecular weight glycopolymers that form a capsule layer on the surface of many bacterial species. This layer serves as a crucial barrier between bacteria and their environment, protecting them from host immune responses and environmental stressors while facilitating adaptation to host niches.
Saroj Khadka, Emily L. Kinney, Brooke E. Ryan, Laura A. Mike   +3 more
wiley   +1 more source

Regulatory Tasks of the Phosphoenolpyruvate-Phosphotransferase System of Pseudomonas putida in Central Carbon Metabolism [PDF]

, 2012
Two branches of the phosphoenolpyruvate-phosphotransferase system (PTS) operate in the soil bacterium Pseudomonas putida KT2440. One branch encompasses a complete set of enzymes for fructose intake (PTSFru), while the other (N-related PTS, or PTSNtr ...
Barabote, Begley, Bradford, Camilli, Cases, Cases, Cases, Cases, Chavarría, Choi, Commichau, Conway, Dauner, del Castillo, Deutscher, Diesterhaft, Eyzaguirre, Fernández, Fischer, Fuhrer, Geer, Gerosa, Grüning, Görke, Holms, Lee, Lee, Lessie, Lüttmann, Miller, Nogales, Perrenoud, Pflüger, Pflüger, Pflüger-Grau, Pflüger-Grau, Portais, Postma, Powell, Puchalka, Reizer, Saier, Saier, Sauer, Sauer, Sawyer, Schleissner, Silva-Rocha, Stock, Tchieu, Van Dijken, Velázquez, Velázquez, Vicente, Vicente, Warren, Zamboni, Zimmer   +57 more
core   +2 more sources

Fructose catabolism and its metabolic effects: Exploring host–microbiota interactions and the impact of ethnicity

The Journal of Physiology, EarlyView.
Abstract figure legend This graphical abstract is a schematic representation highlighting the interactions between dietary fructose, gut microbiota and ethnicity in shaping metabolic health. Abstract Important health disparities are observed in the prevalence of obesity and associated non‐communicable diseases (NCDs), including type 2 diabetes (T2D ...
Florine H.M. Westerbeke, Melany Rios‐Morales, Ilias Attaye, Max Nieuwdorp   +3 more
wiley   +1 more source

FUT8-directed core fucosylation of N-glycans is regulated by the glycan structure and protein environment [PDF]

, 2021
FUT8 is an essential a-1, 6-fucosyltransferase that fucosylates the innermost GlcNAc of N-glycans, a process called core fucosylation. In vitro, FUT8 exhibits substrate preference for the biantennary complex N-glycan oligosaccharide (G0), but the role of
Angulo J., Artschwager R., Clausen H., Corzana F., Delso I., García-García A., Hicks T., Hurtado-Guerrero R., Reichardt N.C., Serna S., Taleb V., Vakhrushev S.Y., Yang Z.   +12 more
core   +1 more source

Regulation of Sugar Metabolism During Fermentation of Brewers' Spent Grain by Leuconostoc pseudomesenteroides DSM20193

Microbial Biotechnology, Volume 18, Issue 4, April 2025.
This study reveals the regulatory mechanism behind sugar metabolism and dextran synthesis by Leuconostoc pseudomesenteroides DSM20193 during the fermentation of a complex substrate like brewers spent grain. Understanding metabolic pathways and genetic adaptation of lactic acid bacteria in food environments can help develop fermented products with ...
Koirala Prabin, Maina Ndegwa, Mojzita Dominik, Coda Rossana   +3 more
wiley   +1 more source

A CTP-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels [PDF]

, 2007
SummaryProteins of the cradle-loop barrel metafold are formed by duplication of a conserved βαβ-element, suggesting a common evolutionary origin from an ancestral group of nucleic acid-binding proteins.
Alva, Vikram, Ammelburg, Moritz, Coles, Murray, Djuranovic, Sergej, Hartmann, Marcus D., Koretke, Kristin K., Lupas, Andrei N., Martin, Jörg, Sauer, Guido, Truffault, Vincent, Zeth, Kornelius   +10 more
core   +1 more source

From Glucose to Green Chemistry: Breakthrough in Microbial Production of Tartaric Semialdehyde

Microbial Biotechnology, Volume 18, Issue 4, April 2025.
L‐(+)‐tartaric acid has extensive applications in many industries. It is formed via a chemical synthesis–enzyme catalysis approach utilising petroleum‐derived C4 lysate. In this study, we employ a combination of metabolic engineering and a modular strategy (“Push‐Pull”) to develop an engineered strain of Gluconobacter oxydans capable of producing ...
Shuangxi Li, Lingcheng Li, Qiwu Jiang, Jianfeng Wang, Xiaoming Sun, Liangliang Zhang, Jianfeng Yuan   +6 more
wiley   +1 more source

Metabolic insights of lactic acid bacteria in reducing off‐flavors and antinutrients in plant‐based fermented dairy alternatives

Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 2, March 2025.
Abstract Multiple sensorial, technological, and nutritional challenges must be overcome when developing plant‐based fermented dairy alternatives (PBFDA) to mimic their dairy counterparts. The elimination of plant‐derived off‐flavors (green, earthy, bitter, astringent) and the degradation of antinutrients are crucial quality factors highlighted by the ...
Guillermo Eduardo Sedó Molina, Geoffrey Ras, Denise Felix da Silva, Lene Duedahl‐Olesen, Egon Bech Hansen, Claus Heiner Bang‐Berthelsen   +5 more
wiley   +1 more source

Metagenomic Exploration Uncovers Several Novel ‘Candidatus’ Species Involved in Acetate Metabolism in High‐Ammonia Thermophilic Biogas Processes

Microbial Biotechnology, Volume 18, Issue 3, March 2025.
Metagenomic analysis of three thermophilic species was performed to identify key species for stable biogas production at high free ammonia levels (> 0.7 g/L). Potential acetogens and syntrophic acetate‐oxidising bacteria (SAOB) were recovered by looking for genes of the Wood–Ljungdahl pathway and glycine synthase reductase pathway.
George B. Cheng, Erik Bongcam‐Rudloff, Anna Schnürer   +2 more
wiley   +1 more source