Results 81 to 90 of about 67,193 (339)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Reversible photobleaching of photoconvertible SAASoti-FP

open access: yesJournal of Biomedical Photonics & Engineering, 2017
SAASoti is a green fluorescent protein suitable for use in super-resolution microscopy as it can be photoconverted to red fluorescence under 405 nm illumination.
Ilya D. Solovyev   +2 more
doaj   +1 more source

Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching

open access: yesEpigenetics & Chromatin, 2014
BackgroundAcetylation of lysine residues in histone tails plays an important role in the regulation of gene transcription. Bromdomains are the readers of acetylated histone marks, and, consequently, bromodomain-containing proteins have a variety of ...
M. Philpott   +9 more
semanticscholar   +1 more source

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

open access: yesAdvanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno   +15 more
wiley   +1 more source

Molecular counting by photobleaching in protein complexes with many subunits: best practices and application to the cellulose synthesis complex

open access: yesMolecular Biology of the Cell, 2014
Fluorescence photobleaching is used to estimate the number of cellulose synthase subunits in Arabidopsis cellulose synthesis complexes. To overcome challenges with counting many (>10) fluorophores from photobleaching traces, a general set of statistical ...
Yalei Chen   +3 more
semanticscholar   +1 more source

Dynamic, Reconfigurable, and Hierarchical Biosynthetic Composites via Collagen Self‐Assembly within Highly Crowded Microgel Pastes

open access: yesAdvanced Materials, EarlyView.
A new approach to extracellular matrix‐mimetic, hierarchical biomaterials is presented. Soft gels composed of overpacked hydrogel microparticle arrays present a biomolecularly crowded environment permissive to the self‐assembly of collagen networks.
Elif Narbay   +11 more
wiley   +1 more source

Effects of second order photobleaching on recovered diffusion parameters from fluorescence photobleaching recovery

open access: yesBiophysical Journal, 1991
In the original theoretical development of fluorescence photobleaching recovery with circular or Gaussian laser intensity profiles (Axelrod et al., 1976, Biophys. J.) the bleaching process is assumed to obey first order kinetics in the fluorescent probe.
Bjarneson, D.W., Petersen, N.O.
openaire   +2 more sources

Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization

open access: yesAdvanced Materials, EarlyView.
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu   +11 more
wiley   +1 more source

Polarize the Solvent to Regulate the Intermediate Phase and Dynamic Crystallization of Perovskite Films

open access: yesAdvanced Materials, EarlyView.
A solvent engineering strategy using polar polymers is introduced to regulate perovskite crystallization dynamics in solar cells. Strongly polarized fluorinated groups stabilize the intermediate phase and control solvent exfoliation, leading to high‐quality films with suppressed defects.
Zhuoqiong Zhang   +14 more
wiley   +1 more source

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