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Photodynamic Diagnosis and Therapy and the Brain
2010Photodynamic techniques such as photodynamic diagnosis (PDD), fluorescence-guided tumour resection (FGR) and photodynamic therapy (PDT) are currently undergoing intensive clinical investigations as adjuvant treatment for malignant brain tumours. The following chapter provides an overview on the current clinical data and trials of PDT as well as ...
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FCLA-assisted photodynamic diagnosis
SPIE Proceedings, 1999Conventional Photo-Dynamic Diagnosis (PDD) has several serious limitations, such as autofluorescence disturbance, poor penetration ability of the exciting laser etc. All these problems are because the exciting laser wavelength at the main absorption peak of the photosensitizer (e. g. HpD) is too short.
Yonghong He +3 more
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Milestones in the development of photodynamic therapy and fluorescence diagnosis
Photochemical & Photobiological Sciences, 2007Many reviews on PDT have been published. This field is now so large, and embraces so many sub-specialties, from laser technology and optical penetration through diffusing media to a number of medical fields including dermatology, gastroenterology, ophthalmology, blood sterilization and treatment of microbial-viral diseases, that it is impossible to ...
Asta, Juzeniene, Qian, Peng, Johan, Moan
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Photodynamic diagnosis in surgery for spinal ependymoma
Journal of Neurosurgery: Spine, 2006Protoporphyrin IX (PPIX), a metabolic product of 5-aminolevulinic acid (5-ALA) accumulating specifically in tumor tissue, shows fluorescence on exposure to excitation light having a peak wavelength of 405 6 1 nm (laser spectrum overlaps that of ultraviolet light), and thus it allows detection of small amounts of tumor.
Satoru, Shimizu +5 more
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Block Copolymer Nanoassemblies for Photodynamic Therapy and Diagnosis
Therapeutic Delivery, 2013Light can be a powerful therapeutic and diagnostic tool. Light-sensitive molecules can be used to develop locally targeted cancer therapeutics. This approach is known as photodynamic therapy (PDT). Similarly, it is possible to diagnose diseases and track the course of treatment in vivo using ligh-sensitive molecules.
Matthew, Dickerson, Younsoo, Bae
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Bronchoscopic photodynamic diagnosis and therapy for lung cancer
Current Opinion in Pulmonary Medicine, 2000Photodynamic diagnosis and therapy have exciting potential in lung cancer management. Fluorescence bronchoscopy enhances the detection of preinvasive lesions and early invasive carcinomas involving the central airways, whereas photodynamic therapy (PDT) provides an effective method for treating these lesions with preservation of lung tissue.
A, Banerjee, J, George
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Photodynamic Therapy and Fluorescence Diagnosis of Skin Cancers
2002In several countries throughout the world the photosensitizer porfimer-sodium has been approved for systemic photodynamic therapy (PDT) for different oncological indications. However, owing to the prolonged photosensitization entailed, the use of this porphyrin derivative is restricted.
Rolf-Markus, Szeimies +1 more
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[Photodynamic diagnosis and photodynamic therapy for experimental hepatoma with ME 2906].
Gan to kagaku ryoho. Cancer & chemotherapy, 2000We studied the effects of photodynamic diagnosis (PDD) and photodynamic therapy (PDT) in confirming the existence of hepatoma, using the new photosensitizer mono-L-aspartyl chlorine 6. Japanese white rabbits were selected for abdominal incision under intravenous anesthesia, and VX 2 tumor cells were transplanted into the left liver lobe to create a ...
J, Nakamura +11 more
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CHAPTER 12. Instrumentation for Clinical Photodynamic Therapy and Photodynamic Diagnosis
2016Both photodynamic therapy (PDT) and photodynamic diagnosis (PDT) require instrumentation (hardware and software) for preclinical research and particularly for clinical translation. Each has basic functional elements in common, regardless of the specific application.
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