Results 1 to 10 of about 16,341 (118)

Growth-coupled selection of 5-aminolevulinic acid synthetase mutants for 5-aminolevulinic acid biosynthesis in Corynebacterium glutamicum [PDF]

Frontiers in Microbiology
Introduction5-Aminolevulinic acid (5-ALA) is a nonprotein amino acid with broad applications in agriculture, medicine, and the food industry. In recent years, substantial efforts have been devoted to enhancing its biosynthesis.
Peng Yang, Peng Yang, Peng Yang, Yutian Fan, Yajuan Zhao, Yan Yu, Xinping Yan, Lu Han, Xinqiang Song, An-dong Gong, An-dong Gong, An-dong Gong   +11 more
doaj   +2 more sources

Supplementation of 5-Aminolevulinic Acid Suppressed Body Weight Loss and Reduced Disease Severity During Eimeria tenella Infection in Broiler Chickens [PDF]

The Journal of Poultry Science
This study aimed to evaluate the effects of 5-aminolevulinic acid (5-ALA) supplementation in broiler chickens infected with Eimeria tenella. To assess these effects, chickens supplemented with 20 ppm 5-ALA (5-ALA group) were compared ...
Taqi Ahmad Hanif, Makoto Matsubayashi, Toshimitsu Hatabu   +2 more
doaj   +2 more sources

5-Aminolevulinic acid improves chicken sperm motility [PDF]

Animal Bioscience, 2021
Objective This study investigated the effects of 5-aminolevulinic acid (5-ALA) on the motility parameters, mitochondrial membrane depolarization, and ATP levels in chicken sperm. Methods The pooled semen from Barred Plymouth Rock males was used.
Shin Taniguchi, Zhendong Zhu, Mei Matsuzaki, Masaoki Tsudzuki, Teruo Maeda   +4 more
doaj   +1 more source

Case Report: Lack of Response to Givosiran in a Case of ALAD Porphyria

Frontiers in Genetics, 2022
Introduction: 5-Aminolevulinic acid dehydratase (ALAD) porphyria (ADP) is an autosomal recessive disease characterized by a profound deficiency in ALAD, the second enzyme in the heme biosynthetic pathway, and acute neurovisceral attacks with abdominal ...
Erica Graff, Karl E. Anderson, Cynthia Levy, Cynthia Levy   +3 more
doaj   +1 more source

Photodynamic therapy of acne

Biomedical Photonics, 2023
Acne is one of the most common skin conditions in the world. A number of studies have shown that photodynamic therapy (PDT) is safe and effective for both inflammatory and non-inflammatory acne and can significantly improve skin conditions in this ...
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj   +1 more source

Photodynamic therapy using systemic administration of 5-aminolevulinic acid and a 410-nm wavelength light-emitting diode for methicillin-resistant Staphylococcus aureus-infected ulcers in mice. [PDF]

PLoS ONE, 2014
Bacterial resistance to antibiotics has become a worldwide problem. One potential alternative for bacterial control is photodynamic therapy. 5-aminolevulinic acid is a natural precursor of the photosensitizer protoporphyrin IX. Relatively little is known
Kuniyuki Morimoto, Toshiyuki Ozawa, Kunio Awazu, Nobuhisa Ito, Norihiro Honda, Sohkichi Matsumoto, Daisuke Tsuruta   +6 more
doaj   +1 more source

Photodynamic therapy of psoriasis

Biomedical Photonics, 2023
Photodynamic therapy (PDT) in the treatment of psoriasis remains the subject of much debate. There is no consensus in the scientific community about effective and safe PDT regimens for psoriasis.
E. V. Filonenko, V. Ivanova-Radkevich
doaj   +1 more source

Synthetic biology-instructed transdermal microneedle patch for traceable photodynamic therapy

Nature Communications, 2022
5-Aminolevulinic acid-based photodynamic therapy heavily depends on the biological transformation efficiency of 5-aminolevulinic acid to protoporphyrin IX, while the lack of an effective delivery system and imaging navigation are major hurdles in ...
Gang He, Yashi Li, Muhammad Rizwan Younis, Lian-Hua Fu, Ting He, Shan Lei, Jing Lin, Peng Huang   +7 more
doaj   +1 more source

The use of 5-aminolevulinic acid and its derivatives in photodynamic therapy and diagnosis [PDF]

Biuletyn Wojskowej Akademii Technicznej, 2018
5-aminolevulinic acid (5-ALA) is used as a drug in the photodynamic therapy (PDT) and photodynamic diagnosis (PDD) of cancer. Combined with irradiation at the appropriate wavelength, it is used as a photosensitizer precursor to identify/kill tumour cells.
Anna Romiszewska, Aneta Bombalska
doaj   +1 more source

5-Aminolevulinic Acid and Red Led in Endodontics: A Narrative Review and Case Report

Gels, 2022
The present study aims to discuss the main factors involving the use of 5-aminolevulinic acid together with red LED light and its application in endodontic treatment through a narrative review and a case report. Persistence of microorganisms remaining on
Simonetta D’Ercole, Teocrito Carlesi, Tatiane Cristina Dotta, Tania Vanessa Pierfelice, Emira D’Amico, Domenico Tripodi, Giovanna Iezzi, Adriano Piattelli, Morena Petrini   +8 more
doaj   +1 more source