Results 41 to 50 of about 21,148 (245)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Blood Pressure Changes After Oral 5-Aminolevulinic Acid Hydrochloride Administered 4–8 h Before TURBT: An Additional Analysis of a Phase III Study (SPP2C102)

Life
This study evaluated changes in blood pressure and hypotension-related adverse drug reactions (ADRs) following oral administration of 5-aminolevulinic acid hydrochloride (5-ALA) in patients undergoing transurethral resection of bladder tumor (TURBT ...
Hideo Fukuhara, Makito Miyake, Keita Kobayashi, Atsushi Ikeda, Kent Kanao, Yoshinobu Komai, Ryo Fujiwara, Yusuke Sato, Rikiya Taoka, Keiji Inoue, Kiyohide Fujimoto, Mototsugu Oya   +11 more
doaj   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

The application of ALA photodynamic fluorescence combined with dermatoscopy in the diagnosis of facial cancerization

Pifu-xingbing zhenliaoxue zazhi
Objective To explore the application of ALA photodynamic fluorescence combined with dermatoscopy in the diagnosis of facial cancerization and precancerous lesions.
XIA Liye, WANG Weiping, SHANG Zhiwei
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Clinical application of photodynamic therapy in endometrial hyperplastic diseases: a review

Photodiagnosis and Photodynamic Therapy
Background and objectives: Endometrial hyperplasia (EH) is a common precancerous condition in gynecology. Conventional treatments are limited by recurrence, side effects, and fertility concerns. Photodynamic therapy (PDT), a minimally invasive and lesion-
Lei Li, Nana Robizonovna Titova, Egor Konstantinovich Slovokhodov, Yuliya Yuryevna Voronina, Mariami Georgievna Kaviladze, Muyang Meng, Natalya Alekseevna Sheshukova, Oksana Vladimirovna Deshchenko, Sergey A. Levakov   +8 more
doaj   +1 more source

A case in which bladder cancer invaded the ureteral orifice and was resected via photodynamic diagnosis‐assisted transurethral resection involving orally administered 5‐aminolevulinic acid

IJU Case Reports, 2019
Introduction Transurethral resection of bladder tumor is widely used in combination with photodynamic diagnosis to treat non‐muscle invasive bladder cancer.
Keitaro Watanabe, Suguru Shirotake, Yuta Umezawa, Takayuki Takahashi, Takeshi Yamanaka, Noriaki LSanto, Takashi Okabe, Gou Kaneko, Katsuhiro Sano, Masanori Yasuda, Kent Kanao, Masafumi Oyama, Koshiro Nishimoto   +12 more
doaj   +1 more source

Phase Engineering of Nanomaterials (PEN): Evolution, Current Challenges, and Future Opportunities

Advanced Materials, EarlyView.
This review summarizes the synthesis, phase transition, advanced characterization spanning ex situ to in situ and operando techniques, and diverse applications of phase engineering of nanomaterials (PEN). It further outlines key challenges and future opportunities, such as phase stability, architecture control, and artificial intelligence (AI)‐driven ...
Ye Chen, Zhanxi Fan, Jingjie Ge, Qiyuan He, Zhuangchai Lai, Jiawei Liu, Chaoliang Tan, Hua Zhang   +7 more
wiley   +1 more source

Effect of extending the oral administration period of 5‐aminolevulinic acid on diagnostic accuracy and treatment outcomes for non–muscle‐invasive bladder cancer

BJUI Compass
Objectives To evaluate the treatment outcomes of 5‐aminolevulinic acid hydrochloride (5‐ALA) photodynamic diagnosis (PDD)‐assisted transurethral resection of bladder tumour (TURBT) (ALA PDD‐TURBT, hereinafter referred to as ‘ALA‐PDD’) exceeding 4 h after
Hideo Fukuhara, Ryu Shigehisa, Shinkuro Yamamoto, Satoshi Fukata, Kenta Saito, Yasuhiko Shibanaka, Keiji Inoue   +6 more
doaj   +1 more source