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Photodynamic therapy in cholangiocarcinomas
Best Practice & Research Clinical Gastroenterology, 2004Symptoms occur late in cholangiocarcinoma and therefore only about half of the patients at the time of diagnosis are candidates for curative surgery. In patients with advanced non-resectable cholangiocarcinoma palliative treatment options are limited. Until now, insertion of endoprostheses for the treatment of cholestasis has been the method of choice.
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Photodynamic therapy for cancer
Nature Reviews Cancer, 2003The therapeutic properties of light have been known for thousands of years, but it was only in the last century that photodynamic therapy (PDT) was developed. At present, PDT is being tested in the clinic for use in oncology--to treat cancers of the head and neck, brain, lung, pancreas, intraperitoneal cavity, breast, prostate and skin.
Dennis E J G J, Dolmans +2 more
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Photodynamic therapy and cancer
BMJ, 2009Promising results need to be followed by development of more selective drugs Photodynamic therapy uses visible light, molecular oxygen (normally present in most tissues at adequate concentration), and an otherwise innocuous drug to destroy tumours.1 All three components are needed for the cytotoxic effect.
Brown, Stanley B., Ibbotson, Sally H.
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Intraperitoneal Photodynamic Therapy
2007Peritoneal carcinomatosis and sarcomatosis are generally incurable problems for which there are few good treatment options. Intraperitoneal PDT is potentially an ideal therapy for peritoneal carcinomatosis because of its relatively superficial treatment effect.
K A, Cengel, E, Glatstein, S M, Hahn
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Lasers in Photodynamic Therapy
Nursing Clinics of North America, 1990Photodynamic therapy has been shown to provide a reasonable alternative to other treatment modalities for patients with certain cancers, and in some cases may be the preferred treatment. Currently, photodynamic therapy is under FDA-approved clinical investigational trials in the treatment of tumors of the skin, bronchus, esophagus, bladder, head and ...
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Photodynamic Therapy for Cholangiocarcinoma
Seminars in Liver Disease, 2004The prognosis of perihilar cholangiocarcinoma (CC) is limited by tumor spread along the biliary tree leading to refractory obstructive cholestasis, cholangitis, and liver failure. Palliation with biliary endoprostheses yields median survival times between 4 and 6 months for nonresectable CC.
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Photodynamic therapy for cholangiocarcinoma
Journal of Hepato-Biliary-Pancreatic Surgery, 2001The prognosis of nonresectable cholangiocarcinoma is dismal, and in Bismuth type III and IV tumors relief of jaundice is seldom achieved, despite successful endoprosthesis insertion. Therefore, we evaluated additional photodynamic therapy in patients who failed to respond to endoprostheses insertion.
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Conquering the Hypoxia Limitation for Photodynamic Therapy
Advanced Materials, 2021Yilin Wan, Lian-Hua Fu, Jing Lin
exaly

