Results 61 to 70 of about 79,111 (306)

AIE‐based drug/gene delivery system: Evolution from fluorescence monitoring alone to augmented therapeutics

Aggregate, Volume 3, Issue 6, December 2022., 2022
The aggregation‐induced emission luminogens (AIEgens) propel the development of drug and gene delivery systems. The lit‐up AIEgens first serve for real‐time monitoring of the delivery processes and evaluation of therapeutic responses of drug/gene. The delicate design of AIEgens to form high‐level structural carrier remarkably enhances the delivery ...
Jie Sun, Xuewen He
wiley   +1 more source

Photodynamic therapy in brain cancer: mechanisms, clinical and preclinical studies and therapeutic challenges

Frontiers in Chemistry, 2023
Cancer is a main cause of death and preferred methods of therapy depend on the type of tumor and its location. Gliomas are the most common primary intracranial tumor, accounting for 81% of malignant brain tumors.
Wojciech Domka, Dorota Bartusik-Aebisher, Izabela Rudy, Klaudia Dynarowicz, Karolina Pięta, David Aebisher   +5 more
doaj   +1 more source

Antifungal photodynamic therapy

Microbiological Research, 2008
In photodynamic antimicrobial chemotherapy (PACT), a combination of a sensitising drug and visible light causes selective destruction of microbial cells. The ability of light-drug combinations to kill microorganisms has been known for over 100 years. However, it is only recently with the beginning of the search for alternative treatments for antibiotic-
Donnelly, Ryan, McCarron, P.A., Tunney, Michael   +2 more
openaire   +4 more sources

Nanohybrid Hydrogel with Dual Functions: Controlled Low‐Temperature Photothermal Antibacterial Activity and Promoted Regeneration for Treating MRSA‐Infected Bone Defects

Advanced Healthcare Materials, EarlyView.
An injectable polydopamine‐based nanohybrid hydrogel integrates controlled low‐temperature photothermal therapy with potent antibacterial efficacy against MRSA while promoting robust bone regeneration. The hydrogel's composite design triggers HSP70 expression, facilitating osteogenesis and efficient bone formation.
Fang Yang, Zewen Shi, Yiwei Hu, Qian Pang, Tianyu Du, Baiyang Song, Jiaqi Zhong, Xiaodong Hu, Weilai Zhu, Junhong Chen, Lin Shi, Xianjun Chen, Qingjiang Pang, Yabin Zhu   +13 more
wiley   +1 more source

Ion−π interactions for constructing organic luminescent materials

Aggregate, Volume 3, Issue 6, December 2022., 2022
The construction of organic fluorescence and room temperature phosphorescence materials by using ion−π interactions including anion−π interactions and cation−π interactions is presented in this minireview. The applications of these ion−π type organic luminescent materials in bioimaging, imaging‐guided anticancer, and antibacterial treatment are also ...
Guoyu Jiang, Jia Yu, Jianguo Wang, Ben Zhong Tang   +3 more
wiley   +1 more source

Tumor‐Targeted Exosome‐Based Heavy Atom‐Free Nanosensitizers With Long‐Lived Excited States for Safe and Effective Sono‐Photodynamic Therapy of Solid Tumors

Advanced Healthcare Materials, EarlyView.
Engineered exosome‐based heavy atom‐free nanosensitizers are developed for safe and targeted sono‐photodynamic therapy of solid tumors. The IR820‐TPE‐loaded, biotin‐conjugated exosomes (IR820‐TPE@B‐Exo) demonstrate significant promise for NIR fluorescence imaging‐guided sono‐photodynamic cancer therapy.
Van‐Nghia Nguyen, Thuy Giang Nguyen Cao, Hyunsun Jeong, Quan Truong Hoang, Binh T. T. Pham, Jieun Bang, Chang Woo Koh, Ji Hee Kang, Jeong Hyun Lee, Xiaofeng Wu, Won Jong Rhee, Young Tag Ko, K. M. K. Swamy, Sungnam Park, JaeHong Park, Min Suk Shim, Juyoung Yoon   +16 more
wiley   +1 more source

Xanthene Dyes for Cancer Imaging and Treatment: A Material Odyssey [PDF]

arXiv, 2022
Cancer is still among the leading health issues today, considering the cost, effectiveness, complexity of detection/treatment modalities and survival rates. One of the most important criteria for higher survival rates is the early and sensitive diagnosis of the disease that can direct the treatment modalities effectively.
arxiv  

Photodynamic Therapy: Esophagus [PDF]

Canadian Journal of Gastroenterology, 2002
Photodynamic therapy (PDT) is a minimally invasive, organ-preserving therapeutic modality, involving three separate components - light, oxygen and a photosensitizing drug. The principles of PDT are described, and the indications for its use are reviewed. Although a widespread clinical application for PDT has not yet emerged, PDT may establish itself as
openaire   +4 more sources

Enhancing Ultrasound Power Transfer: Efficiency, Acoustics, and Future Directions

Advanced Materials, EarlyView.
Implantable devices significantly enhance healthcare but are limited by battery life. Ultrasound power transfer technology offers a promising solution for sustainable operation. This review addresses gaps in current research, particularly in sound field analysis and energy efficiency optimization.
Yi Zheng, Zhuomin Zhang, Yanhu Zhang, Qiqi Pan, Xiaodong Yan, Xuemu Li, Zhengbao Yang   +6 more
wiley   +1 more source

Cancer and electromagnetic radiation therapy: Quo Vadis? [PDF]

arXiv, 2016
In oncology, treating cancer with a beam of photons is a well established therapeutic technique, developed over 100 years, and today over 50% of cancer patients will undergo traditional X-ray radiotherapy. However, ionizing radiation therapy is not the only option, as the high-energy photons delivering their cell-killing radiation energy into cancerous
arxiv