Lipid homeostasis plays a critical role in inherited and acquired retinal diseases. [PDF]
Commun BiolBhattacharyya A, Choudhary V.
europepmc +1 more source
Cell Proliferation, EarlyView.The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao +6 more
wiley +1 more source
Light‐Inducible Activation of FGFR3 Facilitates Chondrocyte Maturation
Cell Proliferation, EarlyView.Light‐inducible activation of FGFR3 induced robust activation of MAPK signaling, promoting proliferation and collagen depositon in induced chondrocytes and prevent the degeneration of osteoarthritic chondrocytes.
Mengze Sun +5 more
wiley +1 more source
Evaluating Human Rod Photoreceptor Function Using Pixelwise Intensity-Based Optoretinography. [PDF]
Transl Vis Sci TechnolYang G, Gaffney M, Cooper RF.
europepmc +1 more source
CERKL gene knockout disturbs photoreceptor outer segment phagocytosis and causes rod-cone dystrophy in zebrafish [PDF]
, 2017 Biswas, Lincoln +17 more
core +1 more source
Cell Proliferation, EarlyView.Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang +8 more
wiley +1 more source
Histologic Photoreceptor and Retinal Pigment Epithelium Degeneration in an Eye With Clinically Documented Geographic Atrophy of AMD. [PDF]
Invest Ophthalmol Vis SciCurcio CA +8 more
europepmc +1 more source
Knockout of Nr2e3 prevents rod photoreceptor differentiation and leads to selective L-/M-cone photoreceptor degeneration in zebrafish [PDF]
, 2019 Han, Shanshan +17 more
core +1 more source
The excitation of photoreceptors
Progress in Biophysics and Molecular Biology, 1969 openaire +2 more sources
A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer
The FEBS Journal, EarlyView.Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge +3 more
wiley +1 more source