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The dynamics of cytosolic calcium in photoreceptor cells

BioEssays, 1995
AbstractAnalysis of the light‐induced changes of cytosolic Ca2+ ([Ca2+]i) in photoreceptor cells has been taken a step further with two recently published studies(1,2). In one, changes in [Ca2+]i were measured in single detached rod outer segments from Gecko in response to various light intensities.
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Strategies for rescue of retinal photoreceptor cells

Current Opinion in Neurobiology, 1993
A variety of genetic and environmental factors cause degeneration of retinal photoreceptors. This review focuses on current strategies to rescue defective, but still viable, rods and cones, including transplantation of normal retinal pigment epithelium cells, corrective gene therapy, administration of survival/growth factors, protection from the ...
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Centrin in the photoreceptor cells of mammalian retinae

Cell Motility, 1995
AbstractPhotoreceptor cells of vertebrate retinae are highly specialized ciliary cells. Their non‐motile ciliated structure is restricted to the so‐called connecting cilium at the joint between the light sensitive outer segment and the metabolically active inner segment. Extensive bidirectional intracellular transport between both segments is forced to
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Stem Cell Epigenetics in Medical Therapy

Medical Epigenetics, 2021
Peng Jin, Liqi Shu
exaly  

A Role for SARM1 in Photoreceptor Cell Death

Photoreceptor cell death is a common feature of many retinal degenerative diseases, leading to incurable vision loss. While there is evidence to support the involvement of cell death pathways such as apoptosis and necroptosis in the degeneration of photoreceptors, the inhibition of these pathways has not been sufficient to rescue photoreceptors and ...
Luke, Gibbons, Sarah, Doyle
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Cell Fate Determination of Photoreceptor Cells

2014
Rods and cones are highly related, sharing many morphological and functional features. Early lineage studies showed that they are produced by mitotic retinal progenitor cells (RPCs) that produce not only photoreceptor cells, but other retinal cell types as well, even in a terminal division (Holt et al., Neuron 1(1):15–26, 1988; Turner and Cepko, Nature
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Photoreceptor Cells

Retina, 1994
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HISTOCHEMICAL STUDIES ON PHOTORECEPTOR CELLS

Annals of the New York Academy of Sciences, 1958
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