Results 271 to 280 of about 107,639 (354)

Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo   +8 more
wiley   +1 more source

Additional file 1: of Photoreceptor proliferation and dysregulation of cell cycle genes in early onset inherited retinal degenerations

open access: green, 2016
Kristin L. Gardiner   +5 more
openalex   +1 more source

Black in Impressionism and Post‐Impressionism: Art, Color Vision, and Psychophysics

open access: yesColor Research &Application, Volume 51, Issue 3, May/June 2026.
Black has engendered controversy in 19th Century color theory and in Impressionist and Post‐Impresssionist painting. The neural mechanisms of blackness perception are being revealed through contemporary psychophysics. ABSTRACT From Paleolithic cave art to modern abstraction, artists have used black not merely as a neutral tone, but as a powerful ...
John S. Werner
wiley   +1 more source

Expression and significance of miR - 20b in retinal photoreceptor cells exposed to PCB1254. [PDF]

open access: yesAging (Albany NY), 2019
Zhang X   +7 more
europepmc   +1 more source

Evolution of Peripheral Visual System in the Apoidea: A Role for Food Item Mobility?

open access: yesEcology and Evolution, Volume 16, Issue 5, May 2026.
Since larger compound eyes and ocelli altogether improve vision, one may expect that insects specialised in chasing very mobile resources possess such morphological optimisation. By analysing 77 species of bees and wasps, we have found that wasps had larger eyes, but not larger ocelli, than bees.
Chiara Francesca Trisoglio   +4 more
wiley   +1 more source

Field‐free programmable bipolar magnetic heterostructures for neuromorphic computing

open access: yesInfoMat, Volume 8, Issue 5, May 2026.
Neuromorphic computing mimics the brain's efficiency, yet typical memristors lack biological synapses' dual signal control. We introduce a magnetic memristor enabling bidirectional, multi‐state modulation without external fields, validated in image feature extraction and neural clustering.
Yaping He   +9 more
wiley   +1 more source

Homozygous Pathogenic Variant in Elongation Factor‐Like 1 (EFL1) as a Causal Factor in Shwachman‐Diamond Syndrome 2 in a Palestinian Child, With Distinct Ocular Manifestations

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
We report a Palestinian female infant with a homozygous pathogenic EFL1 variant (c.3284G>A; p.Arg1095Gln) causing Shwachman–Diamond syndrome type 2 (SDS2). Beyond the classical features of pancytopenia, exocrine pancreatic insufficiency, and growth failure, the patient showed previously unreported ocular manifestations—stage 2–3 retinopathy of ...
Ibrahim Taha   +13 more
wiley   +1 more source

Enhancing the vase life of cut roses through spectral optimisation during greenhouse cultivation

open access: yesAnnals of Applied Biology, Volume 188, Issue 3, Page 656-673, May 2026.
Here, we examined three red‐to‐blue (R:B) light emitting diode (LED) ratios (90:10, 80:20 and 70:30) in two cut rose cultivars. All treatments enhanced photosynthesis, with 90:10 showing the strongest effects—raising chlorophyll, carotenoids, anthocyanins and carbohydrate levels, and extending vase life by up to 30%.
Maryam Davarzani   +6 more
wiley   +1 more source

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