Results 161 to 170 of about 108,777 (309)

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy (OMEGA) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Acta Ophthalmologica, EarlyView.
Abstract Purpose To measure the progression of geographic atrophy (GA) in subjects with age‐related macular degeneration (AMD) in a natural history study. Methods We analysed fundus autofluorescence (FAF) images using a semiautomatic method (RegionFinder) to quantify the GA area in a monocentric study.
Philippe Valmaggia, Georg Ansari, Nadja Inglin, Nils Schärer, Hanna Zuche, Chrysoula Gabrani, Faady Yahya, Marco Cattaneo, Kristina Pfau, Andrea Giani, Marieh Esmaeelpour, Taffeta Chingning Yamaguchi, Christian Prünte, Hendrik P. N. Scholl, Nicolas Feltgen, Leopold Schmetterer, Maximilian Pfau, Peter M. Maloca   +17 more
wiley   +1 more source

Association between metabolic syndrome, macular structures and retinal vascular calibres in the Northern Finland Birth Cohort Eye Study

Acta Ophthalmologica, EarlyView.
Abstract Purpose We aimed to evaluate the association of metabolic syndrome (MetS) with macular thickness and retinal vascular calibres in the population‐based cohort (Northern Finland Birth Cohort). Methods The population of 2242 individuals was divided into MetS (n = 344) and control groups (n = 1898).
Jenni M. Huru, Oona Ahokas, Ilmari L. Leiviskä, Ville O. Saarela, M. Johanna Liinamaa   +4 more
wiley   +1 more source

Histologic Photoreceptor and Retinal Pigment Epithelium Degeneration in an Eye With Clinically Documented Geographic Atrophy of AMD. [PDF]

Invest Ophthalmol Vis Sci
Curcio CA, Messinger JD, Sloan KR, Edwards MM, Bijon J, Huemer F, Leingang O, Freund KB, Berlin A.   +8 more
europepmc   +1 more source

Exploring fundus‐controlled mesopic and scotopic perimetry in inherited retinal disease

Acta Ophthalmologica, EarlyView.
Abstract Purpose Microperimetry is increasingly used as an outcome measure in clinical trials for retinal disease. This study compares mesopic and scotopic microperimetry in a heterogeneous cohort of patients with inherited retinal disease to assess their suitability as clinical trial outcome measures and to determine the most appropriate testing ...
Laura J. Taylor, Amandeep S. Josan, Daniel A O Adeyoju, Isabella Farrance, Robert E. MacLaren   +4 more
wiley   +1 more source

Differences in the Effect of Dopamine on the Phototransduction Between Lampreys and Jawed Vertebrates. [PDF]

Int J Mol Sci
Nikolaeva DA, Rotov AY, Morina IY, Firsov ML, Romanova IV, Astakhova LA.   +5 more
europepmc   +1 more source

Junctional sensitivity and atrophy progression rate of geographic atrophy secondary to age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the baseline junctional retinal sensitivity measured with microperimetry and the atrophy progression rate in eyes with geographic atrophy (GA) secondary to age‐related macular degeneration. Methods In this prospective cohort study, patients with GA were examined with fundus autofluorescence (FAF ...
Alexander Kai Thomsen, Jenni Martinez Villarruel Hinnerskov, Miranda Maung, Aubin Mutschler, SriniVas Sadda, Torben Lykke Sørensen   +5 more
wiley   +1 more source

Axin1 stabilizes S-opsin and maintains cone photoreceptor survival by inhibiting GSK3β activity. [PDF]

Cell Death Discov
Xu J, Man J, Fan Y, Chen Y, Chen Y.
europepmc   +1 more source

Knockout of Nr2e3 prevents rod photoreceptor differentiation and leads to selective L-/M-cone photoreceptor degeneration in zebrafish [PDF]

, 2019
Han, Shanshan, Hu, Xuebin, Huang, Yuwen, Jiang, Tao, Li, Jingzhen, Liu, Fei, Liu, Mugen, Liu, Xiliang, Lv, Yuexia, Qin, Yayun, Qu, Zhen, Reilly, James, Shu, Xinhua, Tang, Zhaohui, Tu, Jiayi, Xie, Shanglun, Yimer, Tinsae Assefa, Yu, Shanshan   +17 more
core   +1 more source

First Insights on Photoreceptor Organ Ultrastructure in Marine Chaetonotida (Gastrotricha): Species of Xenotrichula and Draculiciteria (Xenotrichulidae)

Acta Zoologica, EarlyView.
ABSTRACT Marine gastrotrichs inhabit sediments with limited available light, yet evidence suggests that photoreceptor organs are present throughout the phylum Gastrotricha. Here, we confirm this proposition with ultrastructural descriptions of photoreceptive organs in two species of Xenotrichulidae (Order Chaetonotida) that lack pigmented ocelli ...
Thiago Quintão Araújo, Rick Hochberg
wiley   +1 more source

The P23H Rhodopsin Mouse Model Reveals a Novel Interaction Between the Endoplasmic Reticulum and Connecting Cilium Rootlet Within Photoreceptors. [PDF]

Invest Ophthalmol Vis Sci
Novoselov SS, Mendes BS, Martello A, Wavre-Shapton S, Aguila M, Guarascio R, Ziaka K, Bevilacqua D, Metodieva G, Luthert PJ, Yang J, Metodiev MV, Reeves PJ, Futter CE, Cheetham ME, Burgoyne T.   +15 more
europepmc   +1 more source