Results 61 to 70 of about 44,543 (288)

Wireless sequential dual light delivery for programmed PDT in vivo

Light: Science & Applications
Using photodynamic therapy (PDT) to treat deep-seated cancers is limited due to inefficient delivery of photosensitizers and low tissue penetration of light. Polymeric nanocarriers are widely used for photosensitizer delivery, while the self-quenching of
Jiayi Liu, Bowen Sun, Wenkai Li, Han-Joon Kim, Shu Uin Gan, John S. Ho, Juwita Norasmara Bte Rahmat, Yong Zhang   +7 more
doaj   +1 more source

A Self-Oxygenating Photosensitizer Enhances Photodynamic Antibacterial Therapy In Periodontitis

International Dental Journal
Aim or purpose: There is reduced antibacterial efficacy in hypoxic microenvironments for existing photosensitizers exhibit. So, we designed a photosensitizer with catalytic oxygen-generation properties to enhance the therapeutic effect of antibacterial ...
Liu Yi, Shen Daonan, Ding Yi
doaj   +1 more source

Shaping Rolling Circle Amplification Products into DNA Nanoparticles by Incorporation of Modified Nucleotides and Their Application to In Vitro and In Vivo Delivery of a Photosensitizer

Molecules, 2018
Rolling circle amplification (RCA) is a robust way to generate DNA constructs, which are promising materials for biomedical applications including drug delivery because of their high biocompatibility.
Kyoung-Ran Kim, Pascal Röthlisberger, Seong Jae Kang, Kihwan Nam, Sangyoup Lee, Marcel Hollenstein, Dae-Ro Ahn   +6 more
doaj   +1 more source

Pyrroloquinolines, a New Platform for Developing Organic Photosensitizers: When Synthetic Methodology Meets Photophysics^† [PDF]

, 2022
Zacharias Amara
openalex   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Designing Synthetic Glycosylated Photosensitizers for Photodynamic Therapy [PDF]

, 2020
Parthiban Venkatesan, Priscilla Yoong Mei Yen, Yoshiyuki Uruma, Ping‐Shan Lai   +3 more
openalex   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Trifluoromethyl Boron Dipyrromethene Derivatives as Potential Photosensitizers for Photodynamic Therapy

Molecules, 2018
In this study, two novel boron dipyrromethene-based photosensitizers (BDP3 and BDP6) substituted with three or six trifluoromethyl groups have been synthesized and characterized with various spectroscopic methods, and their photo-physical, photo-chemical,
Jian-Yong Liu, Peng-Zhen Zhou, Jia-Lin Ma, Xiao Jia   +3 more
doaj   +1 more source

Recent Approaches towards the Development of Ru(II) Polypyridyl Complexes for Anticancer Photodynamic Therapy

CHIMIA, 2021
Photodynamic therapy (PDT) is a remarkable alternative or complementary technique to chemotherapy, radiotherapy or immunotherapy to treat certain forms of cancer.
Albert Gandioso, Kallol Purkait, Gilles Gasser   +2 more
doaj   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source