Results 241 to 250 of about 3,233,833 (269)
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IS PENICILLIN A PHOTOSENSITIZING AGENT?
Archives of Dermatology, 1945It is a well known fact that penicillin therapy produces few reactions. Urticaria seems to be the most common cutaneous reaction. In this report the possibility is suggested that penicillin acts as a photosensitizing agent. Photodermatitis of vegetable origin has already been well studied.1It is due in most instances to external contact of the patient
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, 2004
The present study examined the potential of quantum dot bioconjugates to sensitize cells to UV irradiation and to promote the photodynamic activity of the classical photosensitizers such as trifluoperazine (TFPZ) and sulfonated aluminum phthalocyanine ...
R. Bakalova +6 more
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The present study examined the potential of quantum dot bioconjugates to sensitize cells to UV irradiation and to promote the photodynamic activity of the classical photosensitizers such as trifluoperazine (TFPZ) and sulfonated aluminum phthalocyanine ...
R. Bakalova +6 more
semanticscholar +1 more source
Free Radical Biology and Medicine, 1988
Single-strand breaks can be introduced into PM2 closed-circular DNA upon illumination with blue light, in the presence of the anthrapyrazole antitumor agent, compound 1. Damage is observed already after 1 min of blue light illumination, and is significantly enhanced by the presence of electron donors such as NADH, ascorbic acid or Fe(III)/EDTA complex.
Reszka K, J. W. Lown, Hartley Ja
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Single-strand breaks can be introduced into PM2 closed-circular DNA upon illumination with blue light, in the presence of the anthrapyrazole antitumor agent, compound 1. Damage is observed already after 1 min of blue light illumination, and is significantly enhanced by the presence of electron donors such as NADH, ascorbic acid or Fe(III)/EDTA complex.
Reszka K, J. W. Lown, Hartley Ja
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Chemical Communications, 2011
A bi-photosensitizer molecular beacon (bi-PS MB) is assembled by coupling two PS molecules, respectively, onto the opposite ends of a single MB. The MB can be triggered by a tumor marker-survivin mRNA. Fluorescence and cytotoxic (1)O(2) generation occur effectively in breast cancer cells, but not in normal cells.
Yuan Gao +5 more
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A bi-photosensitizer molecular beacon (bi-PS MB) is assembled by coupling two PS molecules, respectively, onto the opposite ends of a single MB. The MB can be triggered by a tumor marker-survivin mRNA. Fluorescence and cytotoxic (1)O(2) generation occur effectively in breast cancer cells, but not in normal cells.
Yuan Gao +5 more
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Activation of a photosensitive pharmaceutical agent by a triboluminescent material
Applied Physics Letters, 2006Given the recent emphasis on applications of triboluminescent materials, we investigate the ability of a triboluminescent material to activate a photosensitive pharmaceutical agent. Using compressed sucrose doped with wintergreen, which luminesces when fractured, we demonstrate the activation of riboflavin (vitamin B2), a photosensitizer.
Magdalena Schreyer +4 more
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GABAergic agents as anticonvulsants in baboons with photosensitive epilepsy
Neuroscience Letters, 1984GABAergic agents have been evaluated for acute anticonvulsant activity in baboons, Papio papio with photosensitive epilepsy. The potent GABAA agonists muscimol and THIP are proconvulsant. (-)Baclofen, 2 mg/kg suppresses myoclonic responses; higher doses facilitate EEG paroxysmal activity.
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Photosensitization by anticancer agents 21: New perylene- and aminonaphthoquinones
Free Radical Biology and Medicine, 1996Hypocrellins are under intensive investigation as photosensitizing agents for photodynamic therapy (PDT). A recent advance in the synthesis of hypocrellin congeners resulted in the production of an amino-substituted hypocrellin-B, and its "half chromophore." Both compounds exhibit stronger red light absorption than previously reported hypocrellins, and,
Gerald G. Miller +8 more
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Journal of Free Radicals in Biology & Medicine, 1986
A novel anthrapyrazole anticancer agent has been examined for photosensitizing properties. Illumination of the anthrapyrazole and ascorbic acid with blue light in aerated aqueous solutions causes SOD and catalase-sensitive oxygen consumption, indicating involvement of both superoxide radical and hydrogen peroxide in this process.
J. W. Lown +2 more
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A novel anthrapyrazole anticancer agent has been examined for photosensitizing properties. Illumination of the anthrapyrazole and ascorbic acid with blue light in aerated aqueous solutions causes SOD and catalase-sensitive oxygen consumption, indicating involvement of both superoxide radical and hydrogen peroxide in this process.
J. W. Lown +2 more
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TREATMENT OF PSORIASIS WITH PHOTOSENSITIZING AGENTS
Archives of Dermatology and Syphilology, 1941The sun's rays appear to be valuable in the treatment of psoriasis, and in most cases the condition improves during the summer months. In many cases of extensive lesions with indurated plaques and in cases in which the condition becomes aggravated rather than improved in the summer, it is possible that the skin is not photosensitive.
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A porphyrin–ruthenium photosensitizer as a potential photodynamic therapy agent
Inorganic Chemistry Communications, 2008Abstract The binding constant of a novel ruthenium–porphyrin to calf thymus DNA is reported. In addition, the ruthenium–porphyrin photocleaves circular plasmid DNA in buffered solutions when irradiated with a 50 W tungsten-halogen lamp. The ruthenium–porphyrin shows the ability to diffuse into normal and skin cancer cells and over a 6 day period in ...
Kyle Davia +3 more
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