Results 11 to 20 of about 9,324 (271)

Enhancing tetraphenylethene cyclization as photoswitch

open access: yesSmart Molecules, 2023
Tetraphenylethene (TPE), a star building block with promising aggregation‐induced emission, has received much interest. Given that its intramolecular Woodward‐Hoffmann cyclic intermediate instantaneously converts back to the original state within several
Yue Wu   +9 more
doaj   +2 more sources

G-quadruplex-based CRISPR photoswitch for spatiotemporal control of genomic modulation

open access: yesNucleic Acids Research, 2023
CRISPR (clustered regularly interspaced short palindromic repeats) technology holds tremendous promise for gene regulation and editing. However, precise control of CRISPR editing is essential to overcome its uncontrollable reaction process and excessive ...
Huaping Deng   +6 more
semanticscholar   +1 more source

Thermally Stable Photomechanical Molecular Hinge: Sterically Hindered Stiff-Stilbene Photoswitch Mechanically Isomerizes

open access: yesJACS Au, 2023
Molecular photoswitches are extensively used as molecular machines because of the small structures, simple motions, and advantages of light including high spatiotemporal resolution.
K. Imato   +6 more
semanticscholar   +1 more source

A red light–responsive photoswitch for deep tissue optogenetics

open access: yesNature Biotechnology, 2022
Red light penetrates deep into mammalian tissues and has low phototoxicity, but few optogenetic tools that use red light have been developed. Here we present MagRed, a red light–activatable photoswitch that consists of a red light–absorbing bacterial ...
Yuto Kuwasaki   +14 more
semanticscholar   +1 more source

Optimizing photoswitchable MEK [PDF]

open access: yesProceedings of the National Academy of Sciences, 2019
SignificanceControlling access to the active sites of kinases using photo-dimerizable domains revolutionizes the types of possible optogenetic perturbations of cell signaling. This technology, however, is useful only when there is strong kinase activity to harness.
Aleena L. Patel   +6 more
openaire   +2 more sources

Diaryltriazolium Photoswitch: Reaching a Millisecond Cycloreversion with High Stability and NIR Absorption.

open access: yesAngewandte Chemie, 2023
The exceptional thermal stability of diarylethene closed isomers enabled many applications but also prevented utilization in photochromic systems that require rapid thermal reversibility.
D. Kolarski   +4 more
semanticscholar   +1 more source

Photoswitchable Anapole Metasurfaces

open access: yesAdvanced Optical Materials, 2021
AbstractNonradiating charge‐current configurations have attracted attention in photonics for the efficient localization of the electromagnetic field. Anapole mode is a unique nonradiating state of light induced by the interference of electric and toroidal dipole that possesses rich physics with potential applications in micro‐nanophotonics.
Wenhao Wang   +4 more
openaire   +2 more sources

Biological Properties of Heparins Modified with an Arylazopyrazole-Based Photoswitch

open access: yesJournal of Medicinal Chemistry, 2023
Unfractionated heparin (UFH) and enoxaparin (Enox) were substituted with a photoswitch (PS) showing quantitative trans–cis and cis–trans photoisomerizations.
Marta Stolarek   +7 more
semanticscholar   +1 more source

Photoswitching neutral homoaromatic hydrocarbons [PDF]

open access: yesNature Chemistry, 2022
Abstract Homoaromatic compounds possess an interrupted π system but display aromatic properties due to through-space or through-bond interactions. Stable neutral homoaromatic hydrocarbons have remained rare and are typically unstable.
Trung Tran Ngoc   +4 more
openaire   +2 more sources

Enlightening Materials with Photoswitches [PDF]

open access: yesAdvanced Materials, 2020
AbstractIncorporating molecular photoswitches into various materials provides unique opportunities for controlling their properties and functions with high spatiotemporal resolution using remote optical stimuli. The great and largely still untapped potential of these photoresponsive systems has not yet been fully exploited due to the fundamental ...
Alexis Goulet‐Hanssens   +2 more
openaire   +3 more sources

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