Results 221 to 230 of about 3,112,354 (260)

A Dual‐Targeted Organic Photothermal Agent for Enhanced Photothermal Therapy

Angewandte Chemie International Edition, 2018
AbstractThe development of highly effective anticancer drugs that cause minimal damage to the surrounding normal tissues is a challenging topic in cancer therapy. Herein, we demonstrate a dual‐targeted organic molecule that functions as a photothermal agent by actively targeting tumor tissue and mitochondria to selectively kill cancer cells.
Hongyu Wang, Jinjie Chang, Mingwan Shi, Wei Pan, Na Li, Bo Tang   +5 more
openaire   +2 more sources

Nanoshells for Photothermal Cancer Therapy

2010
Cancer is a leading cause of death in the United States and contributes to yearly rising health care costs. Current methods of treating cancer involve surgical removal of easily accessible tumors, radiation therapy, and chemotherapy. These methods do not always result in full treatment of the cancer and can in many cases damage healthy cells both ...
Jennifer G, Morton, Emily S, Day, Naomi J, Halas, Jennifer L, West   +3 more
openaire   +2 more sources

Photothermal-driven disassembly of naphthalocyanine nano-photosensitizers for photothermal and photodynamic therapy

Journal of Colloid and Interface Science, 2023
The disassembly of nanomaterials is of particular interest for high-quality imaging and targeted therapies in the field of nanomedicine. In this study, we developed a novel strategy for fabricating self-assembled naphthalocyanine photosensitizers (SiNc@CEL) with intrinsically unique photochemical and photophysical properties.
Wei, Su, Xiantao, Jiang, Ying, Zhang, Chenxiang, Lin, Jun'an, Xiao, Peiyuan, Li   +5 more
openaire   +2 more sources

Reprogramming Tumor Microenvironment with Photothermal Therapy

Bioconjugate Chemistry, 2020
The tumor microenvironment significantly influences cancer progression and therapeutic response. Reprogramming of tumor microenvironment has emerged as a strategy to assist conventional cancer treatment. In recent years, photothermal therapy has received considerable attention owing to its noninvasiveness, high temporal-spatial resolution, and minimal ...
Qinglian Hu, Zemin Huang, Yukun Duan, Zhengwei Fu, null Bin Liu   +4 more
openaire   +2 more sources

Bioproduction of Gold Nanoparticles for Photothermal Therapy

Therapeutic Delivery, 2016
Photothermal response of plasmonic nanomaterials can be utilized for a number of therapeutic applications such as the ablation of solid tumors.Gold nanoparticles were prepared using different methods. After optimization, we applied an aqueous plant extract as the reducing and capping agent of gold and maximized the near-infrared absorption (650-900 nm).
Catarina Oliveira, Silva, Patrícia, Rijo, Jesús, Molpeceres, Lia, Ascensão, Amílcar, Roberto, Ana Sofia, Fernandes, Ricardo, Gomes, João M, Pinto Coelho, Ana, Gabriel, Pedro, Vieira, Catarina Pinto, Reis   +10 more
openaire   +2 more sources

Plasmonic Nanopowders for Photothermal Therapy of Tumors

Langmuir, 2012
We describe a novel strategy for the fabrication of plasmonic nanopowders (dried gold nanoparticles) by using wet chemical nanoparticle synthesis, PEG-SH functionalization, and a standard freeze-drying technique. Our strategy is illustrated by successful fabrication of different plasmonic nanopowders, including gold nanorods, gold-silver nanocages, and
Boris N, Khlebtsov, Elizaveta V, Panfilova, Georgy S, Terentyuk, Irina L, Maksimova, Andrei V, Ivanov, Nikolai G, Khlebtsov   +5 more
openaire   +2 more sources

Polynorepinephrine Nanoparticles: A Novel Photothermal Nanoagent for Chemo-Photothermal Cancer Therapy

ACS Applied Materials & Interfaces, 2019
Novel photothermal nanoagents (PTNAs) with excellent photothermal performance, smart-responsive property, and biocompatibility are in urgent need for precise chemo-photothermal cancer therapy. Herein, polynorepinephrine nanoparticles (PNE NPs) with a high photothermal conversion efficiency (η) of 808 nm laser (67%), pH/thermal responsibility, and ...
Xin Liu, Zhuo Xie, Wei Shi, Zi He, Yang Liu, Huling Su, Yanan Sun, Dongtao Ge   +7 more
openaire   +2 more sources

Strategies on boosting photothermal conversion efficiency of organic molecules for photothermal therapy

Bioorganic Chemistry
As a novel phototherapeutic modality with non-invasiveness, high spatiotemporal resolution, and minimal side effects, photothermal therapy (PTT) has garnered considerable attention in recent years. Diverse photothermal nanoagents (PTNAs) have been developed and substantial achievements have been made in the PTT area, enabling their great clinical ...
Wei, Shao, Feilong, Lu, Xinyi, Ding, Yangyang, Dai, Shunjia, Wu, Wanhua, Lin, Xinwei, Bu, Jinghan, Wang, Xiangyang, Wu, Yujie, Wang, Jun, Chu, Yucheng, Hu, Xiao, Liu, Xuanxin, Wang, Lihong, Li, Wei, Zhang, Chengping, Wen   +16 more
openaire   +2 more sources

Self‐Regenerating Photothermal Agents for Tandem Photothermal and Thermodynamic Tumor Therapy

Small Methods
AbstractSmall molecule‐based photothermal agents (PTAs) hold promising future for photothermal therapy; however, unexpected inactivation exerts negative impacts on their application clinically. Herein, a self‐regenerating PTA strategy is proposed by integrating 2,2′‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic acid) radical cation (ABTS•+) with a ...
Xiangli Li, Yao‐Wen Jiang, Wen‐Jing Tang, Shuzhen Yue, Wei Wang, Huiqin Yao, Junpeng Xu, Zixuan Chen, Jun‐Jie Zhu   +8 more
openaire   +2 more sources

Photothermal amplified multizyme activity for synergistic photothermal-catalytic tumor therapy

Journal of Colloid and Interface Science
Nano-enzymatic catalytic therapy has been widely explored as a promising tumor therapeutic method with specific responsiveness to the tumor microenvironment (TME). However, the inherent lower and simplex catalytic efficiency impairs their anti-tumor efficacy.
Zhichao, Hu, Xue, Zhou, Wei, Zhang, Lingyu, Zhang, Lu, Li, Ying, Gao, Chungang, Wang   +6 more
openaire   +2 more sources