Results 181 to 190 of about 6,711 (234)

Pirfenidone-induced phototoxicity

open access: yesIndian Journal of Pharmacology
Bano, Nazneen   +2 more
openaire   +2 more sources

Phototoxicity in Live Fluorescence Microscopy, and How to Avoid It

open access: yesBioEssays, 2017
Phototoxicity frequently occurs during live fluorescence microscopy, and its consequences are often underestimated. Damage to cellular macromolecules upon excitation light illumination can impair sample physiology, and even lead to sample death.
Michael Weber   +2 more
exaly   +2 more sources

Drug-Induced Phototoxicity: A Systematic Review

open access: yesJournal of the American Academy of Dermatology, 2018
BACKGROUND: Phototoxicity has been attributed to numerous oral drugs over the past 60 years. OBJECTIVE: Determine the quality of evidence supporting suspected phototoxicity from oral drugs.
Henry W Lim, Steven Glassman, Jiyeh Joo
exaly   +2 more sources

Phototoxicity of chlorpromazine

Journal of Medicinal Chemistry, 1979
The constitution of chlorpromazine has been studied in the context of its phototoxicity. Electron transfer from the side chain to the aromatic nucleus of the drug contributes to its instability to light. Even without the side chain, however, chlorophenothiazines appear to be very photolabile, so that it is unlikely that nonphototoxic analogues of ...
N J, Bunce, Y, Kumar, L, Ravanal
openaire   +2 more sources

Retinal Phototoxicity

International Ophthalmology Clinics, 1999
Phototoxic retinal lesions are a product of advances in operative technology. Use of more powerful light sources in both anterior and posterior segment cases and an increase in surgical complexity requiring longer operative times (especially during ophthalmic training) have rendered photic injury a real danger for all surgeons.
W A, Solley, P, Sternberg
openaire   +2 more sources

Skin Phototoxicity of Cosmetic Formulations Containing Photounstable and Photostable UV-Filters and Vitamin A Palmitate

open access: yesToxicology in Vitro, 2013
The aim of this study was to evaluate the in vitro skin phototoxicity of cosmetic formulations containing photounstable and photostable UV-filters and vitamin A palmitate, assessed by two in vitro techniques: 3T3 Neutral Red Uptake Phototoxicity Test and
Patricia Maia Campos, Manfred Liebsch
exaly   +2 more sources

Metalloporphyrin phototoxicity

Journal of Photochemistry and Photobiology B: Biology, 1990
The phototoxicities of six metalloporphyrin dimethylesters (i.e. cobalt (Co), copper (Cu), manganese (Mn), nickel (Ni), tin (Sn) and zinc (Zn) were investigated. Hemolysis of human erythrocytes and inactivation of two enzymes (acetylcholinesterase and beta-galactosidase) were used to assess the phototoxic efficacy of these metal chelates.
J, Scott   +4 more
openaire   +2 more sources

Ocular phototoxicity

Journal of Photochemistry and Photobiology B: Biology, 1988
The human eye is constantly exposed to sunlight and artificial lighting. Therefore the eye is exposed to UV-B (295-320 nm), UV-A (320-400 nm), and visible light (400-700 nm). Light is transmitted through the eye and then signals the brain directing both sight and circadian rhythm. Therefore light absorbed by the eye must be benign.
openaire   +2 more sources

PHOTOTOXIC RETINOPATHY

Ophthalmology Clinics of North America, 2001
Although the occurrence of iatrogenic light-induced retinal toxicity is beyond doubt, several issues remain to be studied further. These include conflicting reports regarding the wavelength of light that is most hazardous; what mechanism contributes more significantly in the pathogenesis of light-induced retinal toxicity-photochemical or photothermal ...
L, Verma, P, Venkatesh, H K, Tewari
openaire   +2 more sources

Shades of phototoxicity in fluorescent imaging agents (that are not supposed to be phototoxic)

Photochemistry and Photobiology, 2023
AbstractThis article is a highlight of the paper by Huang et al. in this issue of Photochemistry and Photobiology. It describes shades of phototoxicity in fluorescent imaging agents that are not intended to be phototoxic. Phototoxicity was assessed using a modified neutral red uptake (NRU) in vitro assay with mean photo‐effects (MPE) for the ...
Serah Essang, Alexander Greer
openaire   +2 more sources

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