Results 11 to 20 of about 32,210 (274)

An Optically Stabilized Fast-Switching Light Emitting Diode as a Light Source for Functional Neuroimaging [PDF]

, 2012
Neuroscience research increasingly relies on optical methods for evoking neuronal activity as well as for measuring it, making bright and stable light sources critical building blocks of modern experimental setups. This paper presents a method to control
Wagenaar, Daniel A.
core   +21 more sources

Cancer targeting with biomolecules: a comparative study of photodynamic therapy efficacy using antibody or lectin conjugated phthalocyanine-PEG gold nanoparticles [PDF]

, 2015
The functionalisation of therapeutic nanoparticle constructs with cancer-specific biomolecules can enable selective tumour accumulation and targeted treatment. Water soluble gold nanoparticles (ca.
Allen, Arap, Bechet, Bertrand, Boya, Bullous, David A. Russell, Davis, Dougherty, Gary-Bobo, Girgis Obaid, Hamblin, Harris, Hogemann-Savellano, Hone, Isabelle Chambrier, Iversen, Jeyaprakash, Jin, Kim, Konska, Kopeček, Lindig, Marín, Mew, Michael J. Cook, Obaid, Oleinick, Orlova, Poiroux, Qualls, Robertson, Ross, Schafer, Schrama, Slamon, Spring, Springer, Stuchinskaya, Sudimack, Tang, Vacha, Wang, Weissenbock, Wieder, Xu, Yarden, Yu, Yu, Zhang   +49 more
core   +1 more source

Practical Implementation of Log-Scale Active Illumination Microscopy [PDF]

, 2010
Active illumination microscopy (AIM) is a method of redistributing dynamic range in a scanning microscope using real-time feedback to control illumination power on a sub-pixel time scale.
K. Chu, Kengyeh, Lim, Daryl, Mertz, Jerome   +2 more
core   +3 more sources

Neuronal imaging with ultrahigh dynamic range multiphoton microscopy [PDF]

, 2017
Multiphoton microscopes are hampered by limited dynamic range, preventing weak sample features from being detected in the presence of strong features, or preventing the capture of unpredictable bursts in sample strength.
Davison, Ian G., Mertz, Jerome, Weber, Timothy D., Witkowski, Ellen D., Yang, Ruohui   +4 more
core   +1 more source

PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin [PDF]

, 2015
The development of novel theranostic agents is an important step in the pathway towards personalised medicine, with the combination of diagnostic and therapeutic modalities into a single treatment agent naturally lending itself to the optimisation and ...
Boyle, Ross W., Bryden, Francesca, Rosca, Elena V., Savoie, Huguette   +3 more
core   +1 more source

Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts [PDF]

, 2013
Platinum diam(m)ine complexes, such as cisplatin, are successful anticancer drugs, but suffer from problems of resistance and side-effects. Photoactivatable PtIV prodrugs offer the potential of targeted drug release and new mechanisms of action.
Bancroft, Brabec, Brabec, Brabec, Butler, Caradonna, Coluccia, Dhara, Eastman, Eastman, Farrell, Farrer, Farrer, Fichtinger-Schepman, Guddneppanavar, Hall, Hamers, Harper, Intini, Jamieson, Kasparkova, Kasparkova, Kauffman, Keck, Kelland, Lau, Lemaire, Mackay, Mackay, Mackay, Najajreh, Ohndorf, O’Dwyer, Pantoja, Phillips, Pracharova, Pregosin, Prokop, Reedijk, Ronconi, Salassa, Salassa, Salassa, Salassa, Siddik, Stehlíková, Still, Suchánková, Tai, Vinje, Vlček, Wang, Westendorf, Westendorf, Westendorf, Wong, Yao, Zenker   +57 more
core   +1 more source

A mechanistic study on the phototoxicity of atorvastatin: singlet oxygen generation by a phenanthrene-like photoproduct [PDF]

, 2009
Atorvastatin calcium (ATV) is one of the most frequently prescribed drugs worldwide. Among the adverse effects observed for this lipid-lowering agent, clinical cases of cutaneous adverse reactions have been reported and associated with photosensitivity ...
IESCE, MARIA ROSARIA, Lhiaubet Vallet V., Miranda M. A., MONTANARO, SARA, PREVITERA, LUCIO   +4 more
core   +1 more source

Citrus limon (Lemon) Phenomenon—A Review of the Chemistry, Pharmacological Properties, Applications in the Modern Pharmaceutical, Food, and Cosmetics Industries, and Biotechnological Studies

Plants, 2020
This review presents important botanical, chemical and pharmacological characteristics of Citrus limon (lemon)—a species with valuable pharmaceutical, cosmetic and culinary (healthy food) properties.
Marta Klimek-Szczykutowicz, Agnieszka Szopa, Halina Ekiert   +2 more
doaj   +1 more source

Titanium Dioxide Induces Apoptosis under UVA Irradiation via the Generation of Lysosomal Membrane Permeabilization-Dependent Reactive Oxygen Species in HaCat Cells

Nanomaterials, 2021
Titanium dioxide nanoparticles (TiO2 NPs) have wide commercial applications, owing to their small size; however, the biosafety of TiO2 NPs should be evaluated further.
In Young Kim, Tae Geol Lee, Vytas Reipa, Min Beom Heo   +3 more
doaj   +1 more source

Intraperitoneal photodynamic therapy causes a capillary-leak syndrome. [PDF]

, 2003
BackgroundIn patients undergoing intraperitoneal (IP) photodynamic therapy (PDT), the combination of aggressive surgical debulking and light therapy causes an apparent systemic capillary-leak syndrome that necessitates significant intensive care unit ...
Canter, Robert J, Fraker, Douglas L, Glatstein, Eli J, Hahn, Stephen M, Kesmodel, Susan B, Metz, James M, Mick, Rosemarie, Raz, Dan J, Spitz, Francis R   +8 more
core   +2 more sources