Results 41 to 50 of about 32,210 (274)

Case Report: Ribociclib-induced phototoxicity presented as dyschromia with subsequent bullae formation

open access: yesFrontiers in Oncology, 2023
Ribociclib, a cyclin-dependent kinase 4/6 inhibitor, is a novel targeted therapy for advanced-stage breast cancer. Although ribociclib-induced cutaneous side effects have been previously noted, they have not been well documented.
Jyun-Yan Jhan   +6 more
doaj   +1 more source

Lipid peroxidation is essential for α-synuclein-induced cell death. [PDF]

open access: yes, 2015
Parkinson's disease is the second most common neurodegenerative disease and its pathogenesis is closely associated with oxidative stress. Deposition of aggregated α-synuclein (α-Syn) occurs in familial and sporadic forms of Parkinson's disease.
Abramov, AY   +5 more
core   +2 more sources

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee   +9 more
wiley   +1 more source

Mitochondria Targeting with Luminescent Rhenium(I) Complexes

open access: yesMolecules, 2017
Two new neutral fac-[Re(CO)3(phen)L] compounds (1,2), with phen = 1,10-phenanthroline and L = O2C(CH2)5CH3 or O2C(CH2)4C≡CH, were synthetized in one-pot procedures from fac-[Re(CO)3(phen)Cl] and the corresponding carboxylic acids, and were fully ...
Joanna Skiba   +9 more
doaj   +1 more source

Evaluation of the cytotoxicity and phototoxicity of Caryocar brasiliense supercritical carbon dioxide extract [PDF]

open access: yes, 2014
Caryocar brasiliense Camb (Pequi) is a typical Brazilian Cerrado fruit tree. Its fruit is used as a vitamin source for culinary purposes and as a source of oil for the manufacture of cosmetics. C.
Lilian FB Amaral   +3 more
core   +1 more source

Human Skin Models in Biophotonics: Materials, Methods, and Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses how the optical properties of human skin can be replicated in human skin models. It describes the principles, materials, and techniques used to develop artificial skin for biophotonics research. Finally, the article highlights recent advances and shows how these models improve the study of light‐skin interactions without the need ...
Dardan Bajrami   +4 more
wiley   +1 more source

Quantification of cellular phototoxicity of organelle stains by the dynamics of microtubule polymerization

open access: yesView
Being able to quantify the phototoxicity of dyes and drugs in live cells allows biologists to better understand cell responses to exogenous stimuli during imaging.
Shivam Mahapatra   +3 more
doaj   +1 more source

Topical minocycline foam 4%: Results of four phase 1 studies evaluating the potential for phototoxicity, photoallergy, sensitization, and cumulative irritation

open access: yesJournal of Immunotoxicology, 2019
FMX101 4% contains 4% micronized minocycline (as an HCl) formulated in a lipophilic foam vehicle for topical administration. FMX101 4% has been shown to be an effective and well-tolerated treatment for moderate-to-severe acne in three Phase 3 pivotal ...
Jonathan Dosik   +2 more
doaj   +1 more source

Sunscreen-Based Photocages for Topical Drugs: A Photophysical and Photochemical Study of A Diclofenac-Avobenzone Dyad

open access: yesMolecules, 2018
Photosensitization by drugs is a problem of increasing importance in modern life. This phenomenon occurs when a chemical substance in the skin is exposed to sunlight.
Isabel Aparici-Espert   +2 more
doaj   +1 more source

The use of non-animal alternatives in the safety evaluations of cosmetics ingredients by the Scientific Committee on Consumer Safety (SCCS) [PDF]

open access: yes, 2015
In Europe, the safety evaluation of cosmetics is based on the safety evaluation of each individual ingredient. Article 3 of the Cosmetics Regulation specifies that a cosmetic product made available on the market is to be safe for human health when used ...
Vinardell Martínez-Hidalgo, Ma. Pilar
core   +2 more sources

Home - About - Disclaimer - Privacy