Results 81 to 90 of about 6,711 (234)
Molecules, 2018 Photosensitization by drugs is a problem of increasing importance in modern life. This phenomenon occurs when a chemical substance in the skin is exposed to sunlight.
Isabel Aparici-Espert +2 more
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Acta Dermato-Venereologica, 1978 A series of agents with alleged photosensitizing properties has been studied in mice by a quantitative in vivo method for acute drug phototoxicity. The method, originally developed for phenothiazine studies, was found suitable for several drug groups with varying mechanism of action, such as tetracyclines, protoporphyrin and psoralens.
B, Ljunggren, H, Möller
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Curvature‐Directed Elongation and Chiral Tilting Drive Asymmetric Tissue Patterning
Advanced Science, EarlyView.Curvature and cell handedness together break tissue symmetry. On convex and concave surfaces, cells elongate along opposite geometric axes and tilt in a consistent chirality‐driven direction, yielding opposite alignment patterns from the same cells. Reversing intrinsic cell chirality reverses both.
Liyao Xu +6 more
wiley +1 more source
Journal of Immunotoxicology, 2019 FMX101 4% contains 4% micronized minocycline (as an HCl) formulated in a lipophilic foam vehicle for topical administration. FMX101 4% has been shown to be an effective and well-tolerated treatment for moderate-to-severe acne in three Phase 3 pivotal ...
Jonathan Dosik +2 more
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Advanced Science, EarlyView.A developmentally guided protocol reproducibly specifies EN1‐positive ventral midbrain dopaminergic (vmDA) progenitors from human pluripotent stem cells and yields functional vmDA neurons. Optogenetic induction of α‐synuclein aggregation elicits selective degeneration of TH‐positive neurons in 2D cultures and 3D neurospheroids, while transplanted ...
Heechang Moon +12 more
wiley +1 more source
Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice
Advanced Science, EarlyView.CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu +8 more
wiley +1 more source
Pyrazinamide-induced phototoxicity: A case report and review of literature
Indian Journal of Dermatology, 2010 A 40-year-old male presented with a fresh case of pulmonary tuberculosis and itchy oozing rashes distributed characteristically over the sun exposed areas of the skin. These rashes had developed since six days following 10 days of start of antitubercular
Katiyar Subodh +2 more
doaj
Frontiers in Microbiology, 2017 Hypericum perforatum L. (Hypericaceae), or St. John's Wort, is a well-known medicinal herb often associated with the treatment of anxiety and depression.
James T. Lyles +8 more
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Photoaugmentation in Drug Phototoxicity
Journal of Investigative Dermatology, 1980 The phototoxic reaction to chlorpromazine and other drugs is provoked by long-wave ultraviolet light (UVA). It was shown by the in vivo mouse tail technique that the reaction is enhanced by medium-wave ultraviolet light (UVB), thus demonstrating the importance of photoaugmentation in this process.
Bjellerup, Mats, Möller, Halvor
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Advanced Science, EarlyView.Atomically precise nanoclusters of Au/Ag alloys are explored as high‐performance photothermal materials, delivering record‐high photothermal efficiencies (up to 91%). Photo‐thermo‐electricity is further demonstrated by integrating nanocluster films with thermoelectric devices.
Avirup Sardar +7 more
wiley +1 more source