Results 1 to 10 of about 2,036 (170)

Asymmetric Dearomatization of Phthalazines by Anion-Binding Catalysis. [PDF]

open access: yesOrg Lett, 2023
A straightforward methodology for the enantioselective synthesis of 1,2-dihydrophthalazines via dearomatization of phthalazines by anion-binding catalysis has been developed. The process involves the Mannich-type addition of silyl ketene acetals to in situ generated N-acylphthalazinium chlorides using a tert-leucine derived thiourea as a H-bond donor ...
Velázquez M   +3 more
europepmc   +6 more sources

Synthesis and In-vitro Antitumor Activity of 1-[3-(Indol-1-yl)prop-1-yn-1-yl]phthalazines and Related Compounds

open access: yesMolecules, 2007
A series of novel 3-(indol-1-yl)prop-1-yn-1-yl-substituted phthalazines and related azines was prepared via a concise pathway by palladium-catalyzed cross-coupling of appropriate halo-azines and N-propargylindoles.
Norbert Haider
exaly   +3 more sources

A Convenient access to thienyl-substituted phthalazines [PDF]

open access: yesJournal of Heterocyclic Chemistry, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Raposo, M. Manuela M.   +2 more
openaire   +4 more sources

Ultrasound-assisted green synthesis and antimicrobial assessment of 1,3-thiazoles and 1,3,4-thiadiazines

open access: yesGreen Chemistry Letters and Reviews, 2021
In this article, we applied ultrasonic irradiation as an ecofriendly, green, efficient approach for the synthesis of a new 1,3-thiazoles and 1,3,4-thiadiazines under solvent-free conditions.
Sara N. Shabaan   +3 more
doaj   +1 more source

Synthesis and characterization of novel phthalazine based push-pull heterocyclic systems for DSSCs [PDF]

open access: yes, 2014
Research on renewable energy sources have been expanding considerably in order to decrease the consumption of fossil fuels and therefore reduce global warming and environmental pollution.
Fernandes, Sara S. M.   +1 more
core   +7 more sources

Phthalazines and phthalazine hybrids as antimicrobial agents: Synthesis and biological evaluation [PDF]

open access: yesJournal of Chemical Research, 2019
Phthalazine and phthalazinone derivatives are important owing to their significant biological activities and pharmacological properties. Herein, a benzoic acid derivative (2), a benzoxazin-1-one derivative (3), and an oxophthalazin-2(1 H)-yl)acetohydrazide (13) are utilized as precursors to construct a novel series of phthalazinones bearing various ...
Asmaa Kamal Mourad   +3 more
openaire   +1 more source

Comparative proteome analysis and thermal stress induced changes in the embryo of poly- and bi-voltine strains of Bombyx mori [PDF]

open access: yes, 2017
Proteins are the ultimate operating molecules producing the physiological effect in all the stages of an organism. As a consequence, proteome of the embryo play a pivotal role in determining the biological structures besides cellular organization and ...
Bhat, Muzafer A.   +2 more
core   +1 more source

Synthesis and Anticancer Activities of Novel 1,4-Disubstituted Phthalazines

open access: yesMolecules, 2006
A series of novel 1-anilino-4-(arylsulfanylmethyl)phthalazines were designed and synthesized. The structures of all the compounds were confirmed by IR, 1H-NMR, elemental analysis and MS.
Ping Gong   +4 more
doaj   +1 more source

Phthalazin-1(2H)-one–picric acid (1/1) [PDF]

open access: yes, 2007
The geometric parameters of the title compound, C8H6N2O·C6H3N3O7, are in the usual ranges. The three nitro groups are almost coplanar with the aromatic picrate ring [dihedral angles 10.2 (2)°, 7.62 (16) and 8.08 (17)°].
Bolte, Michael   +4 more
core   +4 more sources

Synthesis and in vitro evaluation of hydrazinyl phthalazines against malaria parasite, Plasmodium falciparum. [PDF]

open access: yes, 2016
In this report, we describe the synthesis of 1-(Phthalazin-4-yl)-hydrazine using bronsted acidic ionic liquids and demonstrate their ability to inhibit asexual stage development of human malaria parasite, Plasmodium falciparum.
Anusha, S.   +7 more
core   +1 more source

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