Results 41 to 50 of about 326 (161)

Phthalhydrazide Chemiluminescence Method for Determination of Hydroxyl Radical Production: Modifications and Adaptations for Use in Natural Systems

, 2016
The hydroxyl radical is formed through a variety of processes pertinent to natural and anthropogenic systems. Here we report development of a simple and sensitive trap-and-trigger chemiluminescence method based upon the hydroxylation of phthalhydrazide ...
Christopher J. Miller (106133), Andrew L. Rose (1313409), T. David Waite (1313403)   +2 more
core   +1 more source

CARBON DOTS: Bioimaging and Anticancer Drug Delivery

Chemistry – A European Journal, Volume 30, Issue 19, April 2, 2024.
This review explores Carbon Dots (CDs) in cancer treatment, highlighting their synthesis, bioimaging applications, and role in drug delivery. The review details potential barriers to drug delivery, and details recent studies and developments, with a focus on the use of CDs as nanocarriers in drug delivery systems designed for the delivery of ...
Michał Bartkowski, Yingru Zhou, Mustafa Nabil Amin Mustafa, Alexander J. Eustace, Silvia Giordani   +4 more
wiley   +1 more source

B(HSO4)3 as a recyclable solid acid catalyst for the synthesis of 2H-indaxolo [1, 2-b] phthalazine-triones in solvent-free medium [PDF]

, 2014
Boron sulfonic acid was applied as an efficient heterogeneous and reusable catalyst for the synthesis of 2H-indazolo[1,2-b] phthalazine-trione derivatives.
Hamid Reza Safaei
core   +1 more source

Magnetic copper nanoparticle catalyst on β-cyclodextrin-modifed AlFe2O4 for efficient green synthesis 1H-pyrazolo[1,2-b]phthalazine-5,10-diones

Results in Chemistry
This study reports a green, efficient synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones using a novel magnetic copper nanoparticle catalyst, Cu@β-CD@AlFe₂O₄.
Zahra Moghadasi, Jayanti Makasana, Suhas Ballal, Munther Kadheem, Abhayveer Singh, Kattela Chennakesavulu, Pushpa Negi Bhakuni   +6 more
doaj   +1 more source

Solvent-free synthesis of 2H-indazolo[2,1-b] phthalazine-triones promoted by cavitational phenomenon using iodine as catalyst [PDF]

, 2013
An environmentally benign, simple and efficient protocol for the synthesis of 2H-indazolo[2,1-b] phthalazine-triones by condensation of phthalhydrazide, aromatic aldehydes and dimedone under solvent-free ultrasound assisted conditions employing a safe ...
George, Louis, Nizam, Aatika, Kulkarni, Rajani, Varghese, Anitha   +3 more
core   +1 more source

Design, Synthesis, and Evaluation of Inhibitors for Severe Acute Respiratory Syndrome 3C-Like Protease Based on Phthalhydrazide Ketones or Heteroaromatic Esters

, 2016
The 3C-like protease (3CLpro), which controls the severe acute respiratory syndrome (SARS) coronavirus replication, has been identified as a potential target for drug design in the treatment of SARS.
Chunying Niu (2495509), Hanna I. Pettersson (2495506), Jianmin Zhang (69835), John C. Vederas (174316), Carly Huitema (2495503), Jiang Yin (455770), Lindsay D. Eltis (106445), Michael N. G. James (269073)   +7 more
core   +1 more source

Preparation of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones using ZrO₂ nanoparticles as a catalyst under solvent-free conditions

, 2017
Zirconium oxide nanoparticles are an efficient catalyst for the preparation of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones via a three-component reaction of phthalhydrazide, aromatic aldehydes and malononitrile under solvent-free conditions.
Mohammad Piltan
core   +1 more source

Chemiluminescence of 5-(azo-para-phenylene-N-aza-15-crown-5)-phthalhydrazide [PDF]

Arkivoc, 2010
Azo-para-phenylene-N-aza-15-crown-5)-phthalhydrazide presents weak fluorescence and (in the presence of aqueous phosphate buffer at pH = 10.1 with H2O2, with or without Fe 3+ or Cu 2+ ions) a significant chemiluminescence (CL) at λCL = 425 nm. Linear correlations exist between the hydrogen peroxide concentration and the intensity of the CL.
Rodica D. Baratoiu, Lucia Mutihac, Marilena Vasilescu, Mariana Voicescu, Alina Latus, Gabriela Ionita, Adrian Beteringhe, Titus Constantinescu, Alexandru T. Balaban   +8 more
openaire   +1 more source

Phthalazine-triones: Calix[4]arene-assisted Synthesis Using Green Solvents And Their Anticancer Activities Against Human Cancer Cells [PDF]

, 2017
Fourteen phthalazine-triones bearing different substituents at C-4 position were synthesized through multicomponent reactions (MCR) by using phthalhydrazide, dimedone and diferent aldehydes as starting materials, p-sulfonic acid calix[4]arene as catalyst
de Fátima Â., da Silva C.M., da Silva D.L., da Silva J.G., Ruiz A.L.T.G., Rego Y.F., Fernandes S.A., de Carvalho J.E.   +7 more
core   +2 more sources

One-Pot Syntheses of 2H-Indazolo[2,1-B] Phthalazine-Triones Catalyzed by Ionic Iiquid

, 2011
A simple and efficient one-pot method for the preparation of 2H-indazolo [2,1-b] phthalazine-triones from phthalhydrazide, dimedone and aromatic aldehydes has been developed using ionic liquids as catalysts.
Bo Wen Cheng, Xian Lin Xu, Qing Kai Wang, Fang Yang, Yuan Lin Ren, Hong Jun Zang   +5 more
core   +1 more source