Results 31 to 40 of about 326 (161)
Cucurbit[n]uril Analogues: Synthetic and Mechanistic Studies
, 2016 The synthesis of cucurbit[n]uril analogues (18, 19, (±)-20, 33, 34, 35, 36, and 37) is presented. These CB[5], CB[6], and CB[7] analogues all contain bis(phthalhydrazide) walls that are incorporated into the macrocycle. The tailor-made synthesis of these
Lyle Isaacs (365049) +2 more
core +5 more sources
Partial recovery from alloxan-induced diabetes by sodium phthalhydrazide in rats
Biomedicine & Pharmacotherapy, 2017 In the commonly used experimental model of diabetes, a cytotoxic glucose analogue alloxan can selectively destruct pancreatic β-cells, with characteristics similar to the type-1 diabetes (T1D) in humans. Treatment of diabetic rats with sodium phthalhydrazide partially reversed diabetogenic pathology in the alloxan-induced diabetes.
Irina G, Danilova +5 more
openaire +2 more sources
, 2020 A solvent-free synthesis of 2H-indazolo[1,2-b]phthalazinetriones 4 and pyrazolo[1,2-b]phthalazines 6 scaffolds using benzyl alcohol 1 via TEMPO/CAN and TBAB mediated aerobic oxidation, sequential addition-cyclization with phthalhydrazide 2 and β ...
Dalavai Pavithra (8504895) +1 more
core +1 more source
A Simple and Green Protocol for 2H‐Indazolo[2,1‐b]phthalazine‐triones Using Grinding Method
Journal of Chemistry, Volume 2013, Issue 1, 2013., 2013 A robust, facile, and solvent‐free route for the three‐component synthesis of 2H‐indazolo[2,1‐b]phthalazine‐triones in the presence of a catalytic amount of p‐toluene sulfonic acid utilizing grinding has been developed. Short reaction time, simple operation, and high yields are the advantages of this protocol.
Xiao-chuan Jia +6 more
wiley +1 more source
Importance of iron complexation for Fenton-mediated hydroxyl radical production at circumneutral pH
Frontiers in Marine Science, 2016 The reaction between Fe(II) and H2O2 to yield hydroxyl radicals (HO•), the Fenton reaction, is of interest due to its role in trace metal and natural organic matter biogeochemistry, its utility in water treatment and its role in oxidative cell ...
Christopher J. Miller +2 more
doaj +1 more source
, 2017 Preparation and characterization of novel phthalhydrazide-functionalized MCM-41 and its application in the one-pot synthesis of 4-hydroxycoumarin-fused triazolopyrimidines.
Sedigheh Akrami +2 more
core +1 more source
, 2017 A domino reaction of phthalhydrazide and vinylketone in the presence of phosphotungstic acid was established, and 3D turbine-type tetrasubstituted 1H-indazolo[1,2-b]phthalazinedione derivatives were conveniently obtained with up to 95% yield.
Tao Ding +3 more
core +1 more source
Fluorescent and Chemiluminescent Dyes with Aryl Phthalimide and Aryl Luminol Chromophores
ChemPhotoChem, Volume 9, Issue 8, August 2025.A series of photo‐active phthalimides and luminols is prepared by an arylation method from a key precursor. Significant stereoelectronic correlation of the aromatic substituents with the photophysical properties is documented. A new arylated luminol derivative shows a more than three times higher ΦCL than the parent luminol.
Ben C. Bimberg +9 more
wiley +1 more source
, 2022 Bovine Serum Albumin (BSA) was used as a green, inexpensive and efficient biocatalyst, for synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione and 1H-pyrazolo[1,2-a]pyridazine-5,8-dione derivatives through a one-pot three component reaction between ...
Zohreh Habibi (624343) +3 more
core +1 more source
Archiv der Pharmazie, Volume 357, Issue 10, October 2024.Novel phthalazine‐1,4‐dione acetylcholinesterase (AChE) inhibitors with exceptional activity against Alzheimer's disease were synthesized and evaluated. Three compounds, 8m, 8n, and 8p, demonstrated remarkable AChE inhibition similar to donepezil. Molecular docking and dynamic simulations confirmed stability and therapeutic potential as a significant ...
Demokrat Nuha +4 more
wiley +1 more source