Results 1 to 10 of about 253 (66)

A concise study on dimedone: A versatile molecule in multi-component reactions, an outlook to the green reaction media

open access: yesJournal of Saudi Chemical Society, 2018
Dimedone is an interesting and versatile motif in most organic transformations. Its white to light yellow crystals have been utilized as substrate in wide range of organic reactions including multi-component transformations. The notability of dimedone is
Kobra Nikoofar
exaly   +3 more sources

Synthesis of Symmetrical and Non-symmetrical Diimines from Dimedone

open access: yesMolecules, 2009
Symmetrical and non-symmetrical diimines derived from dimedone were synthesized by the reaction of their corresponding enaminothiones with primary amines.
Bahjat A Saeed
exaly   +3 more sources

Selective construction of dispiro[indoline-3,2'-quinoline-3',3''-indoline] and dispiro[indoline-3,2'-pyrrole-3',3''-indoline] via three-component reaction

open access: yesBeilstein Journal of Organic Chemistry, 2023
A convenient synthetic procedure for the construction of novel dispirooxindole motifs was successfully developed by base-promoted three-component reaction of ammonium acetate, isatins and in situ-generated 3-isatyl-1,4-dicarbonyl compounds.
Ziying Xiao   +3 more
doaj   +1 more source

Triethylammonium 2-(3-Hydroxy-2-oxoindolin-3-yl)-5,5-dimethyl-3-oxocyclohex-1-en-1-olate

open access: yesMolbank, 2023
In recent years, the application of privileged structures has become a powerful approach in the discovery of new biologically active molecules. Ion pairing is a strategy used to enhance the permeation of ionized topical drugs.
Yuliya E. Ryzhkova   +2 more
doaj   +1 more source

Aldehydes participation in oxidative stress in rat thymocytes in vitro [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2014
A variety of lipid radicals are formed under oxidative stress development. The further oxidation of these radicals leads to formation of numerous aldehydes.
K. О. Tokarchuk, О. V. Zaitseva
doaj   +1 more source

One-pot synthesis of 2,2'-Arylmethylene bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) by electrochemical method [PDF]

open access: yesشیمی کاربردی روز, 2015
2,2'-Arylmethylene bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives are important biologically active compounds, which can be evaluated as tyrosinase inhibitors.
Reyhaneh Kazemi Rad, Javad Azizian
doaj   +1 more source

Crystal structure, Hirshfeld surface and frontier molecular orbital analysis of 9-(3-bromo-4-hydroxy-5-methoxyphenyl)-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2021
In the fused ring system of the title compound, C24H27BrO5, the mean plane and maximum deviations of the central pyran ring are 0.0384 (2) and 0.0733 (2) Å, respectively.
N. Suresh Babu   +3 more
doaj   +1 more source

Cysteine perthiosulfenic acid (Cys-SSOH): A novel intermediate in thiol-based redox signaling?

open access: yesRedox Biology, 2018
The reversible oxidation of protein cysteine residues (Cys-SH) is a key reaction in cellular redox signaling involving initial formation of sulfenic acids (Cys-SOH), which are commonly detected using selective dimedone-based probes.
David E. Heppner   +11 more
doaj   +1 more source

Synthesis and characterization of selected fused isoxazole and pyrazole derivatives and their antimicrobial activity [PDF]

open access: yesJournal of the Serbian Chemical Society, 2009
New potent antibacterials, fused isoxazole and pyrazole derivatives, were synthesized using 5,5-dimethylcyclohexane-1,3-dione (1) and 3-[(4-chlorobenzylidene)amino]-2-thioxoimidazolidin-4-one (2) as synthons. Aromatic aldehydes on condensation with 1 and
VIJAY V. DABHOLKAR, FAISAL Y. ANSARI
doaj   +3 more sources

Synthesis and Biological Evaluation of Some Newly Synthesized Barbiturates and Their Derivatives by Using Task Specific Ionic Liquid [Bmim]OH

open access: yesOrbital: The Electronic Journal of Chemistry, 2019
Eco-friendly synthesis of some selected Barbiturates, Thiobarbiturates and Dimedone derivatives has been developed by using task specific ionic liquid Bmim[OH], which not only act as catalyst but also  are best solvent media for the Knoevenagel ...
Giribala Madhavrao Bondle   +1 more
doaj   +3 more sources

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