Results 31 to 40 of about 1,271 (129)
Various biologically important 1,8-dioxo-“octahydroxanthene derivatives” have been efficiently synthesized in excellent yields using catalytic amounts of cerium(IV) ammonium nitrate (CAN) in water.
Shitole Nana Vikram +2 more
doaj +1 more source
A Review on Green Synthetic Approaches in the Development of Quinoline Analogues
This review highlights recent advances in environmentally friendly approaches, including metal‐free systems, solvent‐free approaches, microwave, and ultrasonic‐assisted techniques, organo‐ and biocatalysis, ionic liquids, nanoparticle catalysis, electrochemical, and photocatalytic strategies for the synthesis of quinoline scaffolds.
Demis Zelelew +3 more
wiley +1 more source
Novel hexahydroquinazolin-5(6H)-ones 3a-j have been synthesized in good yields by the reaction of enaminones 2a-b with primary amines and formaldehyde under the influence microwaves.
Madhusudhan Saha +3 more
doaj +1 more source
New ylides of two different types were prepared by reaction of 2‐iodosylbenzenesulfonic acid with the corresponding 1,3‐cyclohexanediones under acidic or basic conditions. These compounds have a typical for iodonium ylides structure with the CIC angles 94.18° –97.25° and the IC bond distances between 2.08 and 2.13 Å.
Dmitry M. Noskov +7 more
wiley +1 more source
A green and efficient method for the synthesis of homodimeric (β-dicarbonyl) arylmethanes and dihydropyridine from dimedone in water [PDF]
A direct method has been developed for the synthesis of the dihydropyridine ring system by means of Michael reaction. The reaction of dimedone with 1 .0 equiv. of amines in water provides intermediate product, which allowed dihydropyridine derivatives by
Bayou-Khie, N +4 more
core +1 more source
The multicomponent reaction of 5-aminopyrazole derivatives with cyclic 1,3-dicarbonyl compounds and dimethylformamide dimethylacetal (DMFDMA) in DMF at 150 °C under controlled microwave heating afforded regioselectively 8,9-dihydropyrazolo[1,5-a ...
Kamal Usef Sadek +4 more
doaj +1 more source
Improved Incorporation of Arylglycines Into Ramoplanin Sequences via Solid‐Phase Peptide Synthesis
The incorporation of arylglycines using solid‐phase peptide synthesis remains challenging due to the sensitivity of these residues for epimerization. Here, exploring multiple conditions for the incorporation of arylglycine residues into peptides using SPPS demonstrates how small changes to current synthesis protocols can lead to significant ...
Edward Marschall +3 more
wiley +1 more source
Isotope Effect in the Reaction of 14C-Formaldehyde with Dimedone
Formulae for the specific activity of a labelled product at any stage in a reaction which involves an " isotope effect " are discussed. The investigation of isotope effect by isolating a labelled product in consecutive fractions is illustrated by the ...
AM Downes
core +1 more source
Alum promoted synthesis of 2H-indazolo[2,1-b]phthalazinetrione derivatives in water
A new and efficient synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives from the three-component condensation reaction of phthalhydrazide, dimedone, and aromatic aldehydes using alum [KAl(SO4)2.12H2O] as catalyst was ...
Balaji Rajendra Madje +3 more
doaj +1 more source
Abstract The tumor suppressor protein p16INK4a plays a key role in cell cycle control and is frequently inactivated in human cancers. We previously discovered that oxidation of its single cysteine residue induces a structural transition from the functional monomeric form into inactive amyloid fibrils.
Briana R. Smith +6 more
wiley +1 more source

