Results 51 to 60 of about 4,172 (223)

Facile CuCl2·2H2O catalyzed one-pot conversion of dimedone into highly functionalized indazole based N-arylhydrazinecarbothioamides

Journal of Saudi Chemical Society, 2020
A convenient and facile CuCl2·2H2O catalyzed one-pot synthetic strategy was designed for the conversion of readily available dimedone into highly functionalized N-arylhydrazinecarbothioamide based indazole derivatives. The product yields were found to be
Rafaila Rafique, Syed Muhammad Saad, Arshia, Khalid Mohammed Khan, Shahnaz Perveen, Muhammad Taha   +5 more
doaj   +1 more source

Synthesis of Cyano-Benzylidene Xanthene Synthons Using a Diprotic Brønsted Acid Catalyst, and Their Application as Efficient Inhibitors of Aluminum Corrosion in Alkaline Solutions

Molecules, 2022
Novel cyano-benzylidene xanthene derivatives were synthesized using one-pot and condensation reactions. A diprotic Brønsted acid (i.e., oxalic acid) was used as an effective catalyst for the promotion of the synthesis process of the new starting xanthene–
Mohammed A. Amin, Gaber A. M. Mersal, Morad M. El-Hendawy, Abdallah A. Shaltout, Ali Badawi, Johan Boman, Adil A. Gobouri, Murat Saracoglu, Fatma Kandemirli, Rabah Boukherroub, Jacek Ryl, Mohamed E. Khalifa   +11 more
doaj   +1 more source

Hexahydroquinoline Featuring Amide Functionality: A Promising Scaffold With Calcium Channel Blocking Activity

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT Hexahydroquinoline (HHQ) is a widely recognized scaffold that has garnered considerable attention owing to its diverse pharmacological properties. The structure of HHQ includes a 1,4‐dihydropyridine (DHP) ring, which serves as the pharmacophore for the predominant class of drugs known as calcium channel blockers.
Ebru Koçak Aslan, Kevin Lam, Sun Huang, Göknil Pelin Coşkun, Ayşe Karagüzel, Katrin Denzinger, Kaan Birgül, Mert Ülgen, Jordan W. Nafie, Onur Şahin, Daniel W. Armstrong, Gerald W. Zamponi, Gerhard Wolber, Miyase Gözde Gündüz   +13 more
wiley   +1 more source

Streamlined One‐Pot Synthesis of Fused Pyrroles: A Three‐Component Approach

ChemistryOpen, Volume 15, Issue 4, April 2026.
New modified pyrrole derivatives, namely tetrahydroindol‐4‐ones and pyrrolo[2,3‐d]pyrimidines, functionalized at position 3, were synthesized through a one‐pot multicomponent condensation. Stabilized dimedone enaminones derived from α‐amino acids and their esters (or 6‐amino‐1,3‐dimethyluracil), arylglyoxals, and methylene‐active compounds ...
Kateryna I. Marchenko, Vladislava I. Grinko, Roman M. Gutzul, Oleksandr S. Kharchenko, Henning J. Jessen, Nadiia N. Kolos   +5 more
wiley   +1 more source

Facile and Efficient Synthesis of Xanthene Derivatives Mediated by Lanthanum(III) Nitrate Hexahydrate under Solvent Free Conditions

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2020
The present paper shows that lanthanum(III) nitrate hexahydrate can be used as mild and environment friendly homogeneous catalyst for an efficient one-pot multi-component synthesis of biologically active 1,8-dioxo-octahydroxanthene and 14H-dibenzo[a,j ...
Kabeer Ahmed Shaikh, Uddhav Nivrutti Chaudhar   +1 more
doaj   +1 more source

Proteomic analysis of peptides tagged with dimedone and related probes [PDF]

Journal of Mass Spectrometry, 2014
Owing to its labile nature, a new role for cysteine sulfenic acid (–SOH) modification has emerged. This oxidative modification modulates protein function by acting as a redox switch during cellular signaling. The identification of proteins that undergo this modification represents a methodological challenge, and its resolution remains a matter of ...
Pablo, Martínez-Acedo, Vinayak, Gupta, Kate S, Carroll   +2 more
openaire   +2 more sources

ChemInform Abstract: One‐Pot Four‐Component Synthesis of Some Novel Octahydroquinolindiones Using ZnO as an Efficient Catalyst in Water [PDF]

, 2013
ZnO has been shown to be an inexpensive, efficient, readily available, and mild catalyst for a one-pot four-component synthesis of some novel octahydroquinolindione-3-carboxylic acid ethyl esters using diethylmalonate, dimedone, ammonium acetate, and ...
Aisha Siddekha, ., Pasha, M.A., Sadeq Hamood Saleh Azzam, .   +2 more
core   +1 more source

Peri‐Microvascular Glycogen and Lactate Regulate Capillary Constrictions and Ischemia Outcome in Mice

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Disruption of astrocytic glycogen metabolism, induced by glycogen phosphorylase inhibition (DAB) or genetic deficiency of GYS1 (GYS1Nestin‐KO and GYS1Gfap‐KO), reduces lactate availability to pericytes and impairs microvascular function. This metabolic deficit leads to pericyte‐associated capillary constriction, reduced cerebral blood flow, and ...
Gokhan Uruk, Buket Donmez‐Demir, Sinem Yilmaz‐Ozcan, Canan Cakir‐Aktas, Aslihan Taskiran‐Sag, Gokce Gurler, Jordi Duran, Joan J. Guinovart, Otto Baba, Tsuyoshi Morita, Hulya Karatas, Turgay Dalkara, Muge Yemisci   +12 more
wiley   +1 more source

4a′-Hydroxy-3′,3′,5,6′,6′,7-hexamethyl-3′,4′,4a′,6′,7′,9a′-hexahydrospiro[indole-3,9′-xanthene]-1′,2,8′(1H,2′H,5′H)-trione

Molbank, 2023
Pseudo-multicomponent reactions (Pseudo-MCRs) have led to a variety of compounds with interesting biological properties, especially desirable in the pharmaceutical industry.
Yuliya E. Ryzhkova, Varvara M. Kalashnikova, Fedor V. Ryzhkov, Artem N. Fakhrutdinov, Michail N. Elinson   +4 more
doaj   +1 more source

Histochemical data on the skin mucous cells during the development of the trout [Translation from: Bollettino della Societa Italiana di Biologia Sperimentale 45, 1273-1276, 1969] [PDF]

, 1979
In the skin of Salmo irideus the production of mucus is due to one type of cell specialized as a mucus cell. The histochemical research presented in this paper describes the mucous cells of Salmo irideus and demonstrates observable variation in such ...
Massari, S., Porcelli, F.
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