Development of novel detection reagent for simple and sensitive determination of trace amounts of formaldehyde and its application to flow injection spectrophotometric analysis [PDF]
In this paper, a novel detection reagent for formaldehyde determination is proposed, and is applied to a simple and highly sensitive flow injection method for the spectrophotometric determination of formaldehyde.
Li, Qiong +3 more
core +1 more source
Catalytic Strategies for Amide‐Based Michael Additions: Advances and Perspectives
The Michael addition is a cornerstone transformation in organic synthesis, enabling efficient C–C and C–heteroatom bond formation. Traditionally, α,β‐unsaturated carbonyl compounds such as enones and esters have dominated as Michael acceptors, whereas α,β‐unsaturated amides remain underutilized due to their strong resonance stabilization and low ...
Muhammad Naufal +6 more
wiley +1 more source
A simple and eco-friendly method for the synthesis of novel imidazo[2,1-b][1,3]thiazin derivatives has been developed via the one-pot, three-component and solvent-free reaction of thiohydantoins, aromatic aldehyde and 5,5-dimethylcyclohexane-1,3-dione in
Mohammad Mehdi Ghanbari
doaj +1 more source
Hsp90β‐Selective Inhibitors: Probing the Solvent‐Accessible Frontier
The piperidinol ring of the KUNB106 scaffold (boxed in red) occupies the solvent‐exposed region of the Hsp90β ATP‐binding pocket, which provides a unique opportunity to optimize this region of the molecule. In the study disclosed herein, modifications such as CC bonds, heteroatoms, and three‐dimensionality result in improved inhibitors that further ...
Terin D’Amico +8 more
wiley +1 more source
In the fused ring system of the title compound, C32H37NO4, the central dihydropyridine ring adopts a flattened boat conformation, the mean and maximum deviations of the dihydropyridine ring being 0.1429 (2) and 0.2621 (2) Å, respectively.
N. Suresh Babu +3 more
doaj +1 more source
Applications of Dimedone in the Synthesis of Heterocycles: An Update [PDF]
Dimedone (5,5-dimethylcyclohexane-1,3-dione) is an alicyclic diketone, occasionally considered as building blocks in design and synthesis of a wide variety of heterocycles. The synthetic efficacy of dimedone as a synthon has been presented as a chapter in Advances in Heterocyclic Chemistry in 2009.
Mommahed Heravi, Majid +3 more
openaire +1 more source
The Sulfinate-Sulfone Pummerer Rearrangement [PDF]
alpha-CH acidic sulfoxides with additional electron-withdrawing substitution at C-alpha afford generation of a sulfonyl thioethers during reaction with sulfinyl chlorides.
Schank, Kurt
core +1 more source
State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis +6 more
wiley +1 more source
An efficient synthesis of cycloalkane-1,3-dione-2-spirocyclopropanes from 1,3-cycloalkanediones using (1-aryl-2-bromoethyl)dimethylsulfonium bromides: application to a one-pot synthesis of tetrahydroindol-4(5H)-one [PDF]
An efficient synthesis of cyclohexane- and cyclopentane-1,3-dione-2-spirocyclopropanes from 1,3-cycloalkanediones using sulfonium salts was achieved. The reaction of 1,3-cycloalkanediones with (1-aryl-2-bromoethyl)dimethylsulfonium bromides and powdered ...
Fukumoto Masahiro +4 more
core +2 more sources
H2S Is a Potential Universal Reducing Agent for Prx6‐Type Peroxiredoxins
We report the identification of H2S as reducing agent for Prx6‐type peroxiredoxins. In contrast to common physiological reducing agents of other peroxiredoxins, HS− is small enough to access the active site of oxidized Prx6‐type enzymes in the fully‐folded protein conformation.
Lukas Lang +3 more
wiley +1 more source

